RESUMEN
The performance of the Dutch cattle I&R system was analysed, with emphasis on the potential use of the system for the control of an outbreak of foot and mouth disease (FMD). The analysis showed that not all mutations were centrally registered within the three working days that are allowed to pass between the actual change and the obligatory report. In particular, young calves and cattle heading for slaughter were reported too late. During an outbreak of FMD, the best strategy to trace animals off a farm seems to be first to identify all animals on the farm, using a preprocessed list of the animals that should be present on the farm according to the I&R system. Then all the animals that have left the farm during the last month can be traced in the central I&R computer or by asking the person to whom the farmer sold the cattle (the next owner). In the present study, 54% of the animals were localized within one day, and 94% within one week. Finally, some suggestions for improvement for the system are given.
Asunto(s)
Sistemas de Identificación Animal , Enfermedades de los Bovinos/prevención & control , Bovinos , Fiebre Aftosa/prevención & control , Sistema de Registros , Crianza de Animales Domésticos/organización & administración , Animales , Países BajosRESUMEN
Patients (n = 56) with a diagnosis of chronic idiopathic urticaria were assessed in a fully randomized, double-blind, crossover study to investigate the efficacy of acrivastine at two doses (8 and 4 mg) versus 60 mg terfenadine and placebo administered three times daily. All three active preparations were found to be effective, and significantly better than placebo, in controlling the signs and symptoms of urticaria. No significant differences were found between the active preparations, although in some cases efficacy trends favoured 8 mg acrivastine and terfenadine over 4 mg acrivastine. No significant differences were noted between the active treatments and placebo with regard to reports of drowsiness.
Asunto(s)
Compuestos de Bencidrilo/uso terapéutico , Antagonistas de los Receptores Histamínicos H1/uso terapéutico , Piridinas/uso terapéutico , Triprolidina/uso terapéutico , Urticaria/tratamiento farmacológico , Adulto , Enfermedad Crónica , Ensayos Clínicos como Asunto , Método Doble Ciego , Femenino , Humanos , Masculino , Placebos , Terfenadina , Triprolidina/análogos & derivadosRESUMEN
A controlled, randomized, double-blind trial was performed in 34 hospitalized patients with chronic leg ulcers: 37 ulcerous legs were treated with Elase solution or with saline (placebo) solution. Elase was statistically significantly better in effect on debridement (p less than 0.05) and on enhancing of granulation (p less than 0.05) than saline in patients with chronic venous stasis ulcers. In patients with complex ulcers no statistically significant difference between the two treatments was seen.