RESUMEN
In nuclear medicine, workers handle unsealed radioactive materials. Among the materials, (18)FDG is the most widely used in PET/CT technique. Because of the short half-life of (18)F, it is very challenging to monitor internal exposure of nuclear medicine workers using in vitro bioassay. Thus, the authors developed the new in vitro bioassay methodology for short half-life nuclides. In the methodology, spot urine sample is directly used without normalisation to 1-d urine sample and the spot urinary excretion function was newly proposed. In order to estimate the intake and committed dose for workers dealing (18)FDG, biokinetic models for FDG was also developed. Using the new methodology and biokinetic model, the in vitro bioassay for workers dealing (18)FDG was successfully performed. The authors expect that this methodology will be very useful for internal monitoring of workers who deal short-lived radionuclides in the all field as well as the nuclear medicine field.
Asunto(s)
Fluorodesoxiglucosa F18/orina , Exposición Profesional/análisis , Monitoreo de Radiación/métodos , Radiofármacos/orina , Bioensayo , Humanos , Medicina Nuclear , Dosis de RadiaciónRESUMEN
For the assessment of external doses due to contaminated environment, the dose-rate conversion factors (DCFs) prescribed in Federal Guidance Report 12 (FGR 12) and FGR 13 have been widely used. Recently, there were significant changes in dosimetric models and parameters, which include the use of the Reference Male and Female Phantoms and the revised tissue weighting factors, as well as the updated decay data of radionuclides. In this study, the DCFs for effective and equivalent doses were calculated for three exposure settings: skyshine, groundshine and water immersion. Doses to the Reference Phantoms were calculated by Monte Carlo simulations with the MCNPX 2.7.0 radiation transport code for 26 mono-energy photons between 0.01 and 10 MeV. The transport calculations were performed for the source volume within the cut-off distances practically contributing to the dose rates, which were determined by a simplified calculation model. For small tissues for which the reduction of variances are difficult, the equivalent dose ratios to a larger tissue (with lower statistical errors) nearby were employed to make the calculation efficient. Empirical response functions relating photon energies, and the organ equivalent doses or the effective doses were then derived by the use of cubic-spline fitting of the resulting doses for 26 energy points. The DCFs for all radionuclides considered important were evaluated by combining the photon emission data of the radionuclide and the empirical response functions. Finally, contributions of accompanied beta particles to the skin equivalent doses and the effective doses were calculated separately and added to the DCFs. For radionuclides considered in this study, the new DCFs for the three exposure settings were within ±10 % when compared with DCFs in FGR 13.
Asunto(s)
Radiometría/normas , Aire , Contaminantes Radiactivos del Aire/análisis , Simulación por Computador , Femenino , Humanos , Masculino , Método de Montecarlo , Reactores Nucleares , Fantasmas de Imagen , Fotones , Dosis de Radiación , Monitoreo de Radiación/métodos , Liberación de Radiactividad Peligrosa , Radioisótopos/química , Radiometría/métodos , Valores de Referencia , Suelo , Distribución Tisular , Agua , Contaminantes Radiactivos del Agua/análisisRESUMEN
Probabilistic risk assessment studies use probability distributions for one or more variables of the risk equation in order to quantitatively characterize the variability and uncertainty. In this study, an advanced technique called the two-dimensional Monte Carlo analysis (2D MCA) is applied to estimation of radiological risk for worker and member of the public in the vicinity of the work place for field radiological system in Korea. The variables of the risk model along with the parameters of these variables are described in terms of probability density functions (PDFs). Because the frequencies of normal tasks were far higher than those of accidents, the total risk associated with normal tasks was higher than the accidental risk. The result derived from this work can be used as guidance for the decision-making in controlling the radiological risk in the field of radiography area.