RESUMEN

Non-communicable diseases (NCDs) are the major cause of death worldwide and have economic, psychological, and social impacts. Air pollution is the second, contributing to NCDs-related deaths. Metabolomics are a useful diagnostic and prognostic tool for NCDs, as they allow the identification of biomarkers linked to emerging pathologic processes. The aim of the present study was to review the scientific literature on the application of metabolomics profiling in NCDs and to discuss environmental planning actions to assist healthcare systems and public managers based on early metabolic diagnosis. The search was conducted following PRISMA guidelines using Web of Science, Scopus, and PubMed databases with the following MeSH terms: "metabolomics" AND "noncommunicable diseases" AND "air pollution". Twenty-nine studies were eligible. Eleven involved NCDs prevention, eight addressed diabetes mellitus, insulin resistance, systemic arterial hypertension, or metabolic syndrome. Six studies focused on obesity, two evaluated nonalcoholic fatty liver disease, two studied cancer, and none addressed chronic respiratory diseases. The studies provided insights into the biological pathways associated with NCDs. Understanding the cost of delivering care where there will be a critical increase in NCDs prevalence is crucial to achieving universal health coverage and improving population health by allocating environmental planning and treatment resources.

Asunto(s)

Diabetes Mellitus , Hipertensión , Síndrome Metabólico , Enfermedades no Transmisibles , Humanos , Enfermedades no Transmisibles/epidemiología , Enfermedades no Transmisibles/prevención & control , Diabetes Mellitus/epidemiología , Atención a la Salud

RESUMEN

Studies assessing age and maturation effects on morphological and physical performance measures of young judokas are scarce. This study aimed to assess the independent and combined effects of chronological age and biological maturation on anthropometry and physical performance of 67 judokas aged 11-14. Participants' anthropometric profiles were assessed, and physical performance tests were completed. Multivariate analyses of variance revealed an independent effect of age (anthropometry: F = 1.871; p < 0.05; Pillai's trace = 0.545; η2 p = 0.272; physical performance: F = 2.876; p < 0.01; Pillai's trace = 0.509; η2 p = 0.254) and maturity (anthropometry: F = 10.085; p < 0.01; Pillai's trace = 0.669; η2 p = 0.669; physical performance: F = 11.700; p < 0.01; Pillai's trace = 0.581; η2 p = 0.581). There was no significant combined effect of age and maturity. The maturation effect remained significant when controlled for age (anthropometry: F = 4.097; p < 0.01; Pillai's trace = 0.481; η2 p = 0.481; physical performance: F = 3.859; p < 0.01; Pillai's trace = 0.0.318; η2 p = 0.318). Inadolescent judokas, the maturation effect on growth and physical performance seems to be more relevant than the age effect, leading to the need to control this effect in training routines and competitive events. As in studies with youth soccer players and other youth athletes, bio-banding can be a strategy for controlling maturation in combat sports.