RESUMEN
One hundred ninety-two cases of gonorrhea, of which 23 were extragenital only or both genital and extragenital, were treated with a single oral dose of thiamphenicol (2.5 g in patients weighing less than or equal to 80 kg; 3 g in patients weighing greater than 80 kg). Of the 178 patients whose follow-up was possible, 176 patients (98.9%), including all 23 with extragenital infection (seven pharyngeal and 16 anorectal), recovered completely. The efficacy of the regimen compared favorably with that of other regimens currently used for the treatment of gonorrhea.
Asunto(s)
Enfermedades del Ano/tratamiento farmacológico , Gonorrea/tratamiento farmacológico , Enfermedades Faríngeas/tratamiento farmacológico , Tianfenicol/uso terapéutico , Enfermedades del Ano/etiología , Femenino , Humanos , Masculino , Enfermedades Faríngeas/etiología , Tianfenicol/administración & dosificaciónRESUMEN
After a brief review of the literature on pharyngeal and anorectal gonorrhea, the authors report the incidence of this disease among 498 patients consulting for known or suspected venereal disease from January 1 to December 31 1981. 192 cases of gonorrhoea, of which 23 had extragenital localization, were treated with thiamphenicol (Urfamycine) in a single dose (2.5 g orally or 3 g in patients weighing over 80 kg). Of the 178 patients for whom follow-up was possible, recovery was obtained in 176 (98.9%). All the 23 patients with extragenital infection (7 with pharyngeal gonorrhoea and 16 with anorectal gonorrhoea) recovered completely. The efficacy of this treatment is discussed and compared with that of other antibiotics currently used in gonorrhea.
Asunto(s)
Enfermedades del Ano/epidemiología , Gonorrea/epidemiología , Enfermedades Faríngeas/epidemiología , Enfermedades del Recto/epidemiología , Antibacterianos/uso terapéutico , Femenino , Gonorrea/tratamiento farmacológico , Homosexualidad , Humanos , Masculino , Suiza , Tianfenicol/uso terapéuticoRESUMEN
Appropriate technology, defined here as a low-cost technology aimed at helping to meet the most basic needs of the world's poorest people, can only be a viable proposition if its proponents succeed in making the transition from the first to the second generation, i.e. from the small-scale experiments and pilot innovations of today, to the massive application of new devices (hardware) and new forms of organization (software). The main agents in this second generation are national planning institutions, government ministries, established research centres, development agencies, financial institutions and industral corporations. Some of the ways in which this transition can be facilitated are examined, as well as a number of specific issues such as intelligence policies in appropriate technology, the structure of decision-making mechanisms and the linkage between appropriate technology and overall development strategies.