RESUMEN
HISTORY AND CLINICAL FINDINGS: A 72-year-old female presented with a therapy-resistant diarrhea. EXAMINATIONS: In the case of negative stool cultures and inconspicuous radiological imaging, further endoscopic diagnostics were performed. Histological implicated the image of a celiac disease in the duodenum and lymphocytic colitis reaching into the terminal ileum. In the case of negative antibody detection for celiac disease, a medication side effect was considered by differential diagnosis. TREATMENT: When olmesartan was discontinued, she developed a rapid improvement of the symptoms. CONCLUSION AND DIAGNOSIS: For the angiotensin receptor antagonist olmesartan, the occurrence of a sprue-like enteropathy has rarely described. Microscopic colitis is an exception.