RESUMEN

The biosynthesis of delaminomycin A, produced by Streptomyces albulus MJ202-72F3, was investigated by feeding 13C-labeled compounds followed by 13C NMR analyses. The results indicate that delaminomycin A is derived from six acetate units, five propionate units and one glycine unit.

Asunto(s)

Pirrolidinonas/metabolismo , Receptores de Superficie Celular/antagonistas & inhibidores , Streptomyces/metabolismo , Tetrahidronaftalenos/metabolismo , Isótopos de Carbono , Cromatografía en Capa Delgada , Fermentación , Espectroscopía de Resonancia Magnética , Estructura Molecular , Pirrolidinonas/química , Pirrolidinonas/farmacología , Tetrahidronaftalenos/química , Tetrahidronaftalenos/farmacología