RESUMEN
Thirty-eight patients with a fracture of the posterior wall of the acetabulum were reviewed after 5 (2-12) years. Of 18 patients with successful manual reduction of a femoral head dislocation, a small fracture fragment, no sciatic nerve injury and who were not operated on, 17 had a good result. Of 20 patients who were operated on either because of the large size of the fracture fragment or because of a persistent dislocation of the femoral head, 6 had a poor result due to femoral head necrosis. In these 6 patients the reduction had been delayed and the acetabular osteochondral lesion was more severe than in the other patients. Skeletal traction seems unnecessary in the treatment of acetabular posterior wall fracture.
Asunto(s)
Acetábulo/lesiones , Fracturas Óseas/cirugía , Adolescente , Adulto , Femenino , Cabeza Femoral/lesiones , Estudios de Seguimiento , Fijación de Fractura/métodos , Fracturas Óseas/terapia , Humanos , Luxaciones Articulares/cirugía , Luxaciones Articulares/terapia , Masculino , Persona de Mediana Edad , PronósticoRESUMEN
The effect of one single dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on the antigenic structures of gastric juice glycoproteins, was studied in dogs. Antisera to glycoproteins of the fetal alimentary canal were raised. Histologic mucosal specimens and glycoprotein fractions of gastric juice which were taken from four dogs during a 15.5-month period after MNNG administration, were examined immunohistologically and by immunodiffusion for the appearance of fetal-like antigens. Fetal-like structures appeared in a stepwise manner in both the acid and neutral glycoprotein fractions of the gastric juice, and showed gradual crossreactivity between macromolecules obtained from gastric juice samples obtained during the observation period. Eight immunizations carried out using physicochemically different glycoprotein fractions of fetal canine alimentary canal mucosa, produced a similar response, thus indicating that the same antigenic structures are incorporated into all mucus glycoproteins, even though they do differ physicochemically. It is suggested that this "omnipotential" incorporation picture could also be found after exposure to MNNG and is, by its nature, typically fetal.
Asunto(s)
Proteínas Fetales/análisis , Glicoproteínas/análisis , Lesiones Precancerosas/patología , Neoplasias Gástricas/patología , Animales , Reacciones Cruzadas , Perros , Técnica del Anticuerpo Fluorescente , Jugo Gástrico/análisis , Mucosa Gástrica/embriología , Mucosa Gástrica/patología , Histocitoquímica , Inmunodifusión , Masculino , Metilnitronitrosoguanidina/toxicidadRESUMEN
The study is based on patients with hand injuries treated in the casualty department of Turku University Central Hospital during the years 1971-75 and 1978; there were 4 800 of these patients annually. Hand injuries accounted for 26% of all accidents. Of these patients, 14% were younger than 15, 78% were of working age and only 8% were over 65. Of the adult patients, 3/5 were men. The average age of the men was 35 and of the women 45. Calculated on the basis of our material, the annual number of hand injuries requiring medical attention in Finland was 33 000/10(6) inhabitants. Most hand injuries among adults, 70%, occurred in the home, 28% at work and only some 3% in road accidents. Lacerations of varying degrees of severity constituted 45% of the injuries, fractures 26% and lesser contusions, excoriations and distortions 20%. There were relatively few serious injuries, e.g. 2% of the cases were nerve and tendon lesions; however, the actual workload caused by these injuries was considerable.
Asunto(s)
Traumatismos de la Mano/epidemiología , Accidentes Domésticos , Accidentes de Trabajo , Accidentes de Tránsito , Adolescente , Adulto , Anciano , Femenino , Finlandia , Traumatismos de la Mano/etiología , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Early effects of 10% full-thickness skin burn on subcutaneous tissue PO2 and PCO2 levels were studied in anesthetized rabbits. Tissue gas tensions were determined by means of implanted Silastic tonometers in two different areas in each animal--the burn site itself, and an area remote from the injured tissue. Thermal injury resulted in a rapid, progressive decrease of the tissue PO2 in both locations, with the greatest decrease at the burn site. The minimum PO2 levels were achieved 3-6 hours post burn. The POC2 values increased markedly both in the burn areas and in the distant tissues immediately after the trauma and reached their maximum within 1-3 hours post burn. The greatest accumulation of carbon dioxide occured at the burn site. Six hours after burn the tissue PCO2 levels had been normalized. During the 6-hour observation period the mean arterial PO2 of the burned animals increased gradually from 73 to 95 mmHg, while the mean arterial PCO2 decreased by more than 50% of the original level. The latter effect was probably caused by hyperventilation. Intra-arterial injection of 5 ml of arterial blood from a burned rabbit into a control animal 3 hours post burn induced a significant decrease in cardiac output as well as decline in arterial, intraperitoneal, and tissue PO2 levels in the control rabbit, probably due to a circulatory depressant factor(s) present in the burn blood. When the same test was carried out one hour post burn or with normal blood, no decrease in oxygen tension occurred.