RESUMEN
During a 15-month period, 12,343 consecutive routine urine cultures from female patients were screened for the presence of Gardnerella vaginalis. Of the positive urine cultures, Escherichia coli was found in 1,256 (57%) and presumptive G. vaginalis in 163 (5%). Of the 163 presumptive G. vaginalis isolates, 115 were present in quantitative categories sufficient to suggest the diagnosis of probable urinary tract infection. Of these 115 isolates, 92 were available for specific identification, of which 69 (75%) proved to be G. vaginalis. Comparison of clinical urinary tract diagnoses for the 69 G. vaginalis patients and a matched cohort of E. coli patients showed a significant correlation of E. coli recovery with the diagnosis of urinary tract infection and a significant correlation of G. vaginalis recovery with no urinary tract infection. G. vaginalis was frequently recovered from nonsymptomatic pregnant patients. G. vaginalis appeared at best to be an uncommon urinary tract pathogen.
Asunto(s)
Bacteriuria/orina , Gardnerella vaginalis/aislamiento & purificación , Haemophilus/aislamiento & purificación , Adolescente , Adulto , Factores de Edad , Anciano , Bacteriuria/microbiología , Niño , Preescolar , Escherichia coli/aislamiento & purificación , Femenino , Humanos , Lactante , Recién Nacido , Persona de Mediana Edad , Infecciones Urinarias/diagnóstico , Infecciones Urinarias/microbiología , Vaginitis/diagnóstico , Vaginitis/microbiologíaRESUMEN
Annual ampicillin susceptibility rates for Haemophilus influenzae isolates at the St. Paul-Ramsey Medical Center gradually decreased from 100% in 1974 to 83.3% in 1980 and then remained stable at 88.90%. Penicillin susceptibility rates were similar to those for ampicillin. Ampicillin rates were source dependent: eye 95%, respiratory 90%, miscellaneous sources 82%, and blood and CSF 80%. Rates for Haemophilus parainfluenzae varied and showed no trend. H. parainfluenzae isolates were distinctly less susceptible to penicillin (70%) than to ampicillin (96%). H. influenzae isolates were highly susceptible to chloramphenicol (99.6%) and tetracycline (97.5%), with the latter also showing source dependency. Characterization of isolates for colony morphology and hemolysis showed no clinical relevancy. Ampicillin and penicillin MICs were determined for 128 clinical isolates saved in stock culture during 1978-1983. All 19 resistant isolates (MIC greater than or equal to 4 micrograms/mL) were resistant to both penicillin and ampicillin and produced beta-lactamase. Eight had penicillin MICs of 1 or 2 micrograms/mL and three had ampicillin MICs of 1 or 2 micrograms/mL. The significance of isolates with MICs of 1-2 micrograms/mL is discussed in relation to our findings and a review of the literature.