RESUMEN

Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially Alpinia galanga, Curcuma zedoaria and Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics.

Asunto(s)

Antifúngicos/farmacología , Hongos/efectos de los fármacos , Zingiberaceae/química , Borneo , Farmacorresistencia Fúngica , Etnobotánica , Humanos , Medicina Tradicional , Pruebas de Sensibilidad Microbiana , Micosis/microbiología , Extractos Vegetales/farmacología