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2.
Neurol Med Chir (Tokyo) ; 62(11): 489-501, 2022 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-36223947

RESUMEN

Anterior cervical disc replacement (ACDR) using cervical artificial disc (CAD) has the advantage of maintaining the range of motion (ROM) at the surgical level, subsequently reducing the postoperative risk of adjacent disc disease. Following the approval for the clinical use in Japan, a post-marketing surveillance (PMS) study was conducted for two different types of CAD, namely, Mobi-C (metal-on-plastic design) and Prestige LP (metal-on-metal design). The objective of this prospective observational multicenter study was to analyze the first 2-year surgical results of the PMS study of 1-level ACDR in Japan. A total of 54 patients were registered (Mobi-C, n = 24, MC group; Prestige LP, n = 30, PLP group). Preoperative neurological assessment revealed radiculopathy in 31 patients (57.4%) and myelopathy in 15 patients (27.8%). Preoperative radiological assessment classified the disease category as disc herniation in 15 patients (27.8%), osteophyte in 6 patients (11.1%), and both in 33 patients (61.1%). The postoperative follow-up rates at 6 weeks, 6 months, 1 year, and 2 years after ACDR were 92.6%, 87.0%, 83.3%, and 79.6%, respectively. In both groups, patients' neurological condition improved significantly after surgery. Radiographic assessment revealed loss of mobility at the surgical level in 9.5% of patients in the MC group and in 9.1% of patients in the PLP group. No secondary surgeries at the initial surgical level and no serious adverse events were observed in either group. The present results suggest that 1-level ACDR is safe, although medium- to long-term follow-up is mandatory to further verify the validity of ACDR for Japanese patients.


Asunto(s)
Degeneración del Disco Intervertebral , Desplazamiento del Disco Intervertebral , Disco Intervertebral , Fusión Vertebral , Reeemplazo Total de Disco , Humanos , Reeemplazo Total de Disco/efectos adversos , Reeemplazo Total de Disco/métodos , Japón , Desplazamiento del Disco Intervertebral/diagnóstico por imagen , Desplazamiento del Disco Intervertebral/cirugía , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/cirugía , Estudios de Seguimiento , Resultado del Tratamiento , Degeneración del Disco Intervertebral/diagnóstico por imagen , Degeneración del Disco Intervertebral/cirugía , Degeneración del Disco Intervertebral/etiología , Rango del Movimiento Articular , Vigilancia de Productos Comercializados , Discectomía/métodos , Disco Intervertebral/cirugía
3.
Neurosurg Focus Video ; 4(1): V11, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-36284622

RESUMEN

Surgical treatment of brainstem arteriovenous malformation (AVM) is challenging and associated with a higher risk of complications and a lower rate of gross-total resection. The authors present their experience with the surgical management of lateral pontine AVM using the middle cerebellar peduncle approach. All cases presented with neurological deficits that were caused by hemorrhage before surgery. In all cases, the AVM was not visualized on postoperative angiography, and there was no deterioration of neurological symptoms. In this video, the authors report the treatment results of one case and describe the technique with a review of the literature. The video can be found here: https://youtu.be/bFvEMtMnrKw.

4.
Spine (Phila Pa 1976) ; 42(1): E15-E24, 2017 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-27196020

RESUMEN

STUDY DESIGN: Single-center retrospective case series. OBJECTIVE: To compare outcomes of instrumented fusion and two methods of decompression for degenerative spondylolisthesis. SUMMARY OF BACKGROUND DATA: There is no consensus on the surgical indications or optimum techniques for lumbar degenerative spondylolisthesis. METHODS: We analyzed the data of 140 patients treated by fusion (n = 80; mean follow-up, 77.9 months) or decompression (n = 60; mean follow-up, 38.0 months) and examined changes in surgical indications over a 12-year period. We compared the outcomes of instrumented fusion with the outcomes of two decompression techniques, the first employing a unilateral approach for bilateral decompression and the second employing a bilateral approach for contralateral decompression, with contralateral foraminal decompression as needed. Postoperative evaluation was made at the final follow-up visit beginning in 2007 by analyzing patient interviews and neurological examination data. We compared results with the Japanese Orthopedic Association symptom score before surgery and at final follow-up. RESULTS: Surgical indications for fusion narrowed over time, with fusion used less frequently and decompression used more frequently. Similar decreases in clinical symptoms, including low back pain, were achieved with all methods. In the decompression groups, preoperative slip distance and instability, and postoperative slip progression or development of instability, did not correlate significantly with clinical outcome. Slip progression occurred in 8 of 10 levels in patients with preoperative translation ≥5 mm, but these patients showed no increase in instability, defined as translation ≥ 2 mm, at final follow-up. CONCLUSION: Our findings raise a question about the value of the radiologic criteria for performing fusion used in the late period, namely translation ≥5 mm and/or rotation ≥ 10°. If discogenic pain is excluded, decompression alone may be suitable even for patients with severe low back pain and translation ≥5 mm. LEVEL OF EVIDENCE: 4.


Asunto(s)
Descompresión Quirúrgica/métodos , Laminectomía/métodos , Dolor de la Región Lumbar/cirugía , Vértebras Lumbares/cirugía , Fusión Vertebral/métodos , Espondilolistesis/cirugía , Anciano , Femenino , Estudios de Seguimiento , Humanos , Dolor de la Región Lumbar/diagnóstico por imagen , Vértebras Lumbares/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Estenosis Espinal/diagnóstico por imagen , Estenosis Espinal/cirugía , Espondilolistesis/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
5.
No Shinkei Geka ; 43(11): 991-6, 2015 Nov.
Artículo en Japonés | MEDLINE | ID: mdl-26549719

RESUMEN

Standard strategy for the treatment of subacute in-stent stenosis after carotid artery stenting remains controversial. We report the successful application of stent-in-stenting in 2 patients with subacute in-stent stenosis of the internal carotid arteries (ICA). The postoperative courses of both patients were uneventful, and the patency of the ICA was confirmed at the 2-year follow-up. In this study, medical treatment was not effective, and therefore, stent-in-stenting was used as an alternative treatment for subacute in-stent stenosis.


Asunto(s)
Constricción Patológica/cirugía , Complicaciones Posoperatorias/cirugía , Stents , Anciano , Estenosis Carotídea/cirugía , Constricción Patológica/patología , Humanos , Imagen por Resonancia Magnética , Masculino , Imagen Multimodal , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
6.
Brain Nerve ; 64(7): 855-60, 2012 Jul.
Artículo en Japonés | MEDLINE | ID: mdl-22764357

RESUMEN

Spontaneous intracranial hypotension (SIH) can develop after cerebrospinal fluid (CSF) leakage and is accompanied by various symptoms, including headache and neck pain. In recent years, cases of chronic subdural hematoma (CSDH) that develop concomitantly with SIH have been encountered occasionally. Although various reports regarding the priority of treatment exsist, a conclusive opinion has yet to be given. Here, we present a rare case of CSDH that developed concomitantly with SIH in which the hematoma became organized over a short period of time. Organized CSDH results from impairment of the microcirculation due to metabolic or circulatory dysfunction or inflammation after trepanation. The disease is believed to require craniotomy for treatment, while SIH is frequently treated with an epidural blood patch, which may require repeated procedures to achieve success. If CSF leakage cannot be improved, the concomitant CSDH may become organized. Therefore, it is important to thoroughly discuss the therapeutic options in individual cases.


Asunto(s)
Hematoma Subdural Crónico/complicaciones , Hematoma Subdural Crónico/terapia , Hipotensión Intracraneal/complicaciones , Hipotensión Intracraneal/terapia , Parche de Sangre Epidural/efectos adversos , Pérdida de Líquido Cefalorraquídeo , Rinorrea de Líquido Cefalorraquídeo/cirugía , Craneotomía , Hematoma Subdural Crónico/diagnóstico , Humanos , Hipotensión Intracraneal/diagnóstico , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Reoperación , Factores de Tiempo , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
7.
Neurol Med Chir (Tokyo) ; 45(8): 428-32; discussion 432, 2005 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-16127264

RESUMEN

Silicone plates sutured together to form blocks were used for extradural elevation of the sella floor in two patients who underwent chiasmapexy for visual disturbance associated with empty sella syndrome. A 36-year-old woman had been treated for prolactinoma for about 19 years with bromocriptine and then presented with left visual disturbance. A 79-year-old man presented with right blurred vision of unknown cause other than empty sella. The sella turcica was accessed via the endonasal transsphenoidal approach under endoscopic guidance. The bony sellar floor was opened with a drill. Two or three pieces of 1-mm-thick silicone plate were sutured to make a block. Two or three blocks were inserted into the epidural space to elevate the sellar contents. Visual symptoms improved in both patients. Silicone is biocompatible and not absorbable. Silicone plates are elastic and easy to handle during insertion, but firm enough to support the sella. The elevation can be adjusted by changing the number of plates in the block. The endonasal endoscopic approach is minimally invasive and particularly suitable for transsphenoidal extradural chiasmapexy for empty sella syndrome.


Asunto(s)
Síndrome de Silla Turca Vacía/cirugía , Endoscopía/métodos , Procedimientos Neuroquirúrgicos/métodos , Quiasma Óptico/cirugía , Prótesis e Implantes/tendencias , Silla Turca/cirugía , Adulto , Anciano , Atrofia/inducido químicamente , Atrofia/patología , Atrofia/cirugía , Bromocriptina/efectos adversos , Síndrome de Silla Turca Vacía/etiología , Síndrome de Silla Turca Vacía/patología , Femenino , Antagonistas de Hormonas/efectos adversos , Humanos , Masculino , Cavidad Nasal/anatomía & histología , Cavidad Nasal/cirugía , Procedimientos Neuroquirúrgicos/instrumentación , Quiasma Óptico/lesiones , Quiasma Óptico/fisiopatología , Prolactinoma/tratamiento farmacológico , Prolactinoma/patología , Silla Turca/patología , Siliconas/uso terapéutico , Resultado del Tratamiento , Trastornos de la Visión/etiología , Trastornos de la Visión/fisiopatología , Trastornos de la Visión/cirugía
8.
J Neurosurg ; 102(5): 938-9, 2005 May.
Artículo en Inglés | MEDLINE | ID: mdl-15926726

RESUMEN

Reconstruction of the sellar floor after pituitary tumor removal is sometimes difficult because the repair graft is difficult to handle in the narrow space. This is especially problematic if the endonasal endoscopic approach is used. The authors devised a technique to facilitate this procedure by placing a suture knot on the repair splint. This allows the material to be grasped securely with forceps and improves manipulation even within the narrow nasal cavity. This technique has proved useful when performing the endonasal endoscopic approach, and it is also expected to be useful when conducting the conventional sublabial transsphenoidal approach.


Asunto(s)
Endoscopía/métodos , Silla Turca/cirugía , Férulas (Fijadores) , Suturas , Humanos , Nariz , Neoplasias Hipofisarias/cirugía
9.
Neurosurgery ; 56(3): E627; discussion E627, 2005 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15730594

RESUMEN

OBJECTIVE AND IMPORTANCE: Repair of a cerebrospinal fluid leak is not always easy, especially when a large fistula, with concomitant infection and injured mucosa, has developed from repeated transsphenoidal operations. We repaired such a sellar floor defect with mucosal flaps via the endonasal endoscopic approach and finally obliterated the fistula by promoting granulation-like tissue formation with recombinant human basic fibroblast growth factor (bFGF). CLINICAL PRESENTATION: A 27-year-old woman with intractable cerebrospinal fluid rhinorrhea was referred to our department after repeated operations for a relapsing Rathke's cleft cyst. Endonasal endoscopic examination revealed a large bone defect on the sellar floor through which previously packed fat and fascia were exposed to the nasal cavity. INTERVENTION: Mucosal flaps were harvested endoscopically from the nasal septum and the superior and middle turbinates. These pedicled flaps were transposed to the sellar defect. The flaps survived but did not cover the whole area, resulting in gaps between the flaps through which cerebrospinal fluid still leaked. Recombinant bFGF was repeatedly applied endoscopically to the mucosal flaps. The flaps turned into granulation-like tissue, and complete mucosal covering was finally achieved. CONCLUSION: bFGF has a wide range of biological effects, including stimulation of fibroblast growth and promotion of angiogenesis. It accelerates wound healing and is used clinically to treat dermal ulcers. The method presented here to treat an intractable fistula with mucosal flap and recombinant bFGF may suggest a new clinical application of bFGF. This possibility should be examined in a large number of patients in the future.


Asunto(s)
Rinorrea de Líquido Cefalorraquídeo/cirugía , Factor 2 de Crecimiento de Fibroblastos/uso terapéutico , Cavidad Nasal/cirugía , Complicaciones Posoperatorias/cirugía , Fístula del Sistema Respiratorio/cirugía , Silla Turca/cirugía , Colgajos Quirúrgicos , Anciano , Quistes del Sistema Nervioso Central/cirugía , Rinorrea de Líquido Cefalorraquídeo/etiología , Femenino , Factor 2 de Crecimiento de Fibroblastos/administración & dosificación , Factor 2 de Crecimiento de Fibroblastos/farmacología , Tejido de Granulación/efectos de los fármacos , Humanos , Hidrocefalia/etiología , Hidrocefalia/cirugía , Meningitis Bacterianas/complicaciones , Neumocéfalo/etiología , Proteínas Recombinantes/administración & dosificación , Proteínas Recombinantes/farmacología , Proteínas Recombinantes/uso terapéutico , Recurrencia , Fístula del Sistema Respiratorio/etiología , Derivación Ventriculoperitoneal , Cicatrización de Heridas/efectos de los fármacos
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