1.
Anal Methods
; 13(7): 874-883, 2021 02 25.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33576354
RESUMEN
Using the children's toy, Shrinky-Dink©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 1 ag mL-1 of the S1 subunit of the spike protein.
Asunto(s)
Técnicas Biosensibles/métodos , Técnicas Electroquímicas/métodos , Poliestirenos/química , SARS-CoV-2/química , Saliva/química , Glicoproteína de la Espiga del Coronavirus/análisis , Aptámeros de Nucleótidos/química , Técnicas Electroquímicas/instrumentación , Electrodos , Oro/química , Humanos , Límite de Detección , Dominios Proteicos , Glicoproteína de la Espiga del Coronavirus/química
2.
medRxiv
; 2020 Nov 18.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33236028
RESUMEN
Using the children's toy, Shrinky-Dink ©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 0.1 fg mL -1 of the S1 subunit of the spike protein.