RESUMEN

The specific features of disseminated pulmonary tuberculosis were studied in patients isolating Mycobacterium tuberculosis (MBT) with a high (n = 135) and low (n = 50) viability. The degree of the pathogen's viability was shown to determine the clinical characteristics of a specific process and the efficiency of its treatment. It is speculated that there is a direct relationship between the viability ofmycobacteria and their virulence. There are differences in the nature of primary drug resistance in MBT with their varying variability.

Asunto(s)

Antituberculosos/farmacología , Mycobacterium tuberculosis/efectos de los fármacos , Mycobacterium tuberculosis/fisiología , Tuberculosis Miliar/tratamiento farmacológico , Tuberculosis Miliar/microbiología , Tuberculosis Pulmonar/tratamiento farmacológico , Tuberculosis Pulmonar/microbiología , Adulto , Medios de Cultivo , Farmacorresistencia Bacteriana , Femenino , Hospitalización , Humanos , Masculino , Persona de Mediana Edad , Mycobacterium tuberculosis/crecimiento & desarrollo , Mycobacterium tuberculosis/aislamiento & purificación , Mycobacterium tuberculosis/patogenicidad , Población Rural , Siberia , Esputo/microbiología , Tuberculosis Miliar/sangre , Tuberculosis Miliar/diagnóstico , Tuberculosis Pulmonar/sangre , Tuberculosis Pulmonar/diagnóstico , Virulencia

Asunto(s)

Hemodinámica , Perfusión , Animales , Presión Sanguínea , Perros , Modelos Biológicos , Flujo Sanguíneo Regional , Resistencia Vascular