RESUMEN

Neuropeptide Y (NPY) was studied as a marker for neuroblastoma in 12 children. All but one patient with neuroblastoma had elevated plasma NPY concentrations at diagnosis. During treatment NPY values returned to normal in 9 of 12 children. All three children without normalization of plasma NPY values died; two of them had a relapse and the third died of toxic effects. Plasma NPY appears to be a sensitive marker of neuroblastoma.

Asunto(s)

Biomarcadores de Tumor/sangre , Neuroblastoma/diagnóstico , Neuropéptido Y/sangre , Adolescente , Niño , Preescolar , Femenino , Ácido Homovanílico/sangre , Humanos , Lactante , Masculino , Neuroblastoma/sangre , Neuroblastoma/terapia , Fosfopiruvato Hidratasa/sangre , Ácido Vanilmandélico/sangre