RESUMEN

The report concerns a mother who breast fed her infant whilst receiving sodium aurothiomalate for the treatment of rheumatoid arthritis. The milk:serum concentration ratio was not constant, reflecting the non-concurrence of the concentration-time profiles of gold in milk and maternal serum after i.m. injection. Gold was detected in the infant's serum. Calculations indicate that the weight-adjusted dose to the infant exceeded that received by the mother.

Asunto(s)

Tiomalato Sódico de Oro/farmacocinética , Lactancia , Leche Humana/metabolismo , Adulto , Artritis Reumatoide/tratamiento farmacológico , Artritis Reumatoide/metabolismo , Femenino , Oro/sangre , Oro/metabolismo , Tiomalato Sódico de Oro/sangre , Tiomalato Sódico de Oro/uso terapéutico , Humanos , Lactante , Inyecciones Intramusculares , Embarazo