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Plant Cell Rep ; 24(5): 312-7, 2005 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15818489

RESUMEN

The accumulation of podophyllotoxin (PTOX) and 6-methoxypodophyllotoxin (6MPTOX) was enhanced about twofold in the suspension culture of Linum album line 2-5 aH following the addition of methyl jasmonate (MeJas) to the cultivation medium, reaching 7.69+/-1.45 mg/g dry weight and 1.11+/-0.09 mg/g dry weight, respectively. There was no increase in 6MPTOX accumulation following the addition of MeJas to suspension cells of L. album line X4SF, whereas PTOX accumulation was enhanced about tenfold to 0.49+/-0.10 mg/g dry weight. Phenylalanine ammonia-lyase activity increased immediately after the addition of MeJas to a cell suspension culture of line X4SF, reaching a maximum between 4 h and 1 day after elicitation, while cinnamyl alcohol dehydrogenase activity and the lignin content of the cells were not affected.


Asunto(s)
Acetatos/farmacología , Ciclopentanos/farmacología , Lino/metabolismo , Lignanos/biosíntesis , Podofilotoxina/biosíntesis , Oxidorreductasas de Alcohol/biosíntesis , Técnicas de Cultivo de Célula , Lino/efectos de los fármacos , Oxilipinas , Fenilanina Amoníaco-Liasa/biosíntesis
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