RESUMEN
OBJECTIVE: To evaluate the medium-term effect and stability of the schistosomiasis comprehensive control strategy based on infectious source control after its popularization and application in marshland endemic areas. METHODS: The schistosomiasis comprehensive control strategy based on infectious source control including "replacing buffalo with machine", "marshlands isolation and grazing forbidden", etc. was implemented in all villages of Sanli Township, a heavy endemic area with schistosomiasis in Jianxian County. The infection situation of schistosomiasis in population and Oncomelania snails in 4 villages around the lake were monitored regularly for 6 consecutive years. RESULTS: The infection rate of schistosomiasis in population significantly decreased after the comprehensive control measures were carried out. Two years later, the infection rate in Huangjia Village was 0, and was sustained at zero for 5 consecutive years; the infection rate in Fengfu Village decreased by 77.24% and stabilized to zero for the next three years; the population infection rates in Fanrong Village and Caomen Village decreased by 82.33% and 82.53%, respectively, then the infection rates of the two villages kept under 1% and were 0 for 2 years and 1 year, respectively. The number of spots with infected snails in two marshlands in pilot areas decreased yearly from 10 before the intervention to 0, in which, the infection rate of snails and the number of spots with infected snails in Huangjiaoniu Marshland and Goulian Marshland decreased to zero 1 year and 3 years after the strategy was implemented, respectively, and the infected snails were not found in these marshlands in following years. CONCLUSION: Strengthening the management of buffaloes in surrounding areas and utilizing marshland resources is the main measure that can consolidate and expand the medium-term and long-term effect of the schistosomiasis 2.2 comprehensive strategy based on infectious source control.