RESUMEN
Chordoid glioma of the third ventricle is a recently characterized primary neoplasm of the central nervous system. We present a case and discuss the pathologic and radiologic features. We are aware of only 16 other cases documented in the world literature. This radiologic-pathologic correlation alerts pathologists and radiologists to recognize chordoid glioma as a distinct clinicopathologic entity restricted to the third ventricular area of adult patients.
Asunto(s)
Neoplasias del Plexo Coroideo/patología , Glioma/patología , Tercer Ventrículo/patología , Adulto , Biomarcadores de Tumor/metabolismo , Encéfalo/diagnóstico por imagen , Neoplasias del Plexo Coroideo/química , Neoplasias del Plexo Coroideo/diagnóstico por imagen , Glioma/química , Glioma/diagnóstico por imagen , Humanos , Inmunohistoquímica , Imagen por Resonancia Magnética , Masculino , Proteínas de Neoplasias/metabolismo , Tercer Ventrículo/diagnóstico por imagen , Tomografía Computarizada por Rayos XRESUMEN
Giardiasis is a common intestinal infection which commonly presents with nonspecific symptoms. Suspected cases are usually diagnosed by stool examination or duodenal aspirates or biopsies. The purpose of this case report is to alert physicians to the fact that the organism may be present in colonic and ileal biopsies when clinical symptoms prompt a clinician to perform colonic biopsies rather than the usual tests of stools and duodenal aspirates or biopsies.
Asunto(s)
Colon/parasitología , Giardiasis/diagnóstico , Íleon/parasitología , Adulto , Biopsia , Colon/patología , Giardiasis/parasitología , Humanos , Íleon/patología , MasculinoRESUMEN
We decided to determine whether Toxoplasma gondii-specific IgM or IgG is produced locally or is deposited in the aqueous humor of T gondii-naive cats after primary or secondary inoculation with T gondii. Cats were orally inoculated with T gondii tissue cysts during weeks 0 and 36. Aqueous humor and serum T gondii-specific IgM and IgG were measured, using ELISA, during weeks 0, 2, 4, 6, 8, 12, 16, 20, 26, 34, 38, 40, 42, 44, 48, 56, 62, 66, and 72 after primary oral inoculation. Total immunoglobulin-based Goldmann-Witmer coefficients were calculated to verify intraocular antibody production. Toxoplasma gondii-specific IgM was not detected in the aqueous humor of any cat. Data indicate that cats have transient local production of T gondii-specific IgG in the aqueous humor after primary and secondary oral inoculations with T gondii tissue cysts. The intraocular immune response to systemic T gondii infection may signal ocular recruitment of antigen-specific lymphocytes that function independently from the general humoral response to T gondii infection. Cautious interpretation of results that suggest intraocular production of T gondii-specific IgG in cats with uveitis is warranted.