Asunto(s)
Disfunción Eréctil/tratamiento farmacológico , Disfunción Eréctil/economía , Política de Salud/tendencias , Cobertura del Seguro/ética , National Health Insurance, United States , Inhibidores de Fosfodiesterasa 5/economía , Inhibidores de Fosfodiesterasa 5/uso terapéutico , Disfunción Eréctil/complicaciones , Disfunción Eréctil/epidemiología , Humanos , Seguro de Servicios Farmacéuticos , Masculino , Principios Morales , Inhibidores de Fosfodiesterasa 5/efectos adversos , Prevalencia , Estados UnidosRESUMEN
The resting metabolic rates (RMR) of 60 lean and obese men, aged 18-82 y and weighing 60-171 kg, were measured and body compositions were determined. Body compositional variables reflecting active protoplasmic tissue were all highly interrelated. Body weight alone gave prediction values for RMR that were comparable to those of other variables of active protoplasmic tissue mass. Regional distribution of fat had no influence on the RMR and the influence of age on RMR was trivial. The classic prediction equations and tables overestimate RMR of men. The 95%-confidence limits for both lean and obese men were broad. This conclusively demonstrates that metabolic efficiency is not necessarily or exclusively related to obesity. New regression equations for predicting the RMR based on weight and fat-free mass were developed: RMR = 879 + 10.2 WT kg and RMR = 290 + 22.3 FFMD kg, where FFMD is fat-free mass from densitometry measurements.
Asunto(s)
Ingestión de Energía , Adulto , Anciano , Antropometría , Metabolismo Basal , Composición Corporal , Peso Corporal , Calorimetría Indirecta , Densitometría , Femenino , Humanos , Masculino , Persona de Mediana Edad , Necesidades Nutricionales , Obesidad/metabolismo , Grosor de los Pliegues CutáneosRESUMEN
Pancreatic islet transplantation into cryptorchid testes resulted in near-complete normalization of hepatic enzymic parameters associated with glycogen metabolism. Measurements of plasma glucose levels and of immunoreactive insulin levels indicated that islet transplantation also resulted in improved control of glycemia in diabetic animals receiving these grafts. Electron microscopic examination of cryptorchid testes revealed the presence of islet cells in the interstitial spaces outside of the seminiferous tubules. These islet cells both had granules identified as B granules by morphologic criteria and appeared to be actively secreting the contents of these granules. This site of islet transplantation appeared to provide a protected site which facilitated long-term survival and continued functioning of islet grafts.