RESUMEN

Radical and transition metal-catalyzed cascade cyclization strategies were investigated with respect to the synthesis of the tetracyclic core of the augustamine-type Amaryllidaceae alkaloids. These studies resulted in the synthesis of noraugustamine and the development of an oxidative Heck/aza-Wacker cascade forming two rings, a C-N bond, and an all-carbon quaternary center in a single step.

Asunto(s)

Alcaloides de Amaryllidaceae , Alcaloides de Amaryllidaceae/química , Ciclización , Estructura Molecular , Oxidación-Reducción , Estrés Oxidativo

RESUMEN

Held June 24-25, 2021, the third annual Empowering Women in Organic Chemistry (EWOC) conference gathered organic chemists at all stages of the career pipeline for rich professional development opportunities and a showcase of recent scientific achievements. This Meeting Review outlines the program.