1.
Chem Commun (Camb)
; 51(19): 4001-4, 2015 Mar 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-25622946
RESUMEN
The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into ß-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.
Asunto(s)
Oligopéptidos/química , Peptidomiméticos/química , Procesos Fotoquímicos , Ácido Acético/química , Secuencia de Aminoácidos , Estructura Secundaria de Proteína
2.
Org Lett
; 3(16): 2537-8, 2001 Aug 09.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11483054
RESUMEN
[reaction: see text] Functionalized alpha-hydroxyallenes 1 were smoothly converted into the corresponding 2,5-dihydrofurans 2 by using 5-10 mol % of gold(III) chloride as catalyst. This mild and efficient cyclization method can be applied to alkyl- and alkenyl-substituted allenes at room temperature, furnishing tri- and tetrasubstituted dihydrofurans in good to excellent chemical yields and with complete axis to center chirality transfer.