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1.
Eat Behav ; 5(1): 55-66, 2004 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-15000954

RESUMEN

OBJECTIVE: We examined weight dissatisfaction (actual weight minus self-stated ideal weight) and weight goal (normative weight minus self-stated ideal weight) subjective indices in a large clinical sample to determine how the indices discriminate between diagnostic categories and relate to other measures of body image disturbance. METHOD: Approximately 200 anorexic, bulimic, and eating disorder not otherwise specified (NOS) participants reported their self-stated ideal weight and completed the Mizes Anorectic Cognitions (MAC) Questionnaire, Eating Disorders Inventory (EDI), and Restraint Scale-Revised. RESULTS: Compared with bulimic and NOS participants, anorexics reported less weight dissatisfaction but had an ideal weight that is farthest from normative weight. The weight dissatisfaction measure correlates well with other measures of body image disturbance, and both measures show evidence of discriminant validity. DISCUSSION: These two measures highlight the substantial differences in the nature of body image disturbance between the eating disorder diagnostic groups. Theoretical, clinical, and practical implications are discussed.


Asunto(s)
Anorexia Nerviosa/psicología , Actitud Frente a la Salud , Imagen Corporal , Peso Corporal , Bulimia/psicología , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Distorsión de la Percepción , Inventario de Personalidad/estadística & datos numéricos , Adolescente , Adulto , Anorexia Nerviosa/diagnóstico , Bulimia/diagnóstico , Trastornos de Alimentación y de la Ingestión de Alimentos/diagnóstico , Femenino , Humanos , Masculino , Satisfacción Personal , Psicometría/estadística & datos numéricos , Valores de Referencia , Reproducibilidad de los Resultados
2.
J Behav Ther Exp Psychiatry ; 34(3-4): 293-312, 2003.
Artículo en Inglés | MEDLINE | ID: mdl-14972675

RESUMEN

The present study compared the effects of creating an acceptance versus a control treatment context on the avoidance of aversive interoceptive stimulation. Sixty high anxiety sensitive females were exposed to two 10-min periods of 10% carbon dioxide enriched air, an anxiogenic stimulus. Before each inhalation period, participants underwent a training procedure aimed at encouraging them either to mindfully observe (acceptance context) or to control symptoms via diaphragmatic breathing (control context). A third group was given no particular training or instructions. We hypothesized that an acceptance rather than control context would be more useful in the reduction of anxious avoidance. Compared to control context and no-instruction participants, acceptance context participants were less avoidant behaviorally and reported less intense fear and cognitive symptoms and fewer catastrophic thoughts during the CO(2) inhalations. We discuss the implications of our findings for an acceptance-focused vs. control-focused context when conducting clinical interventions for panic and other anxiety disorders.


Asunto(s)
Ejercicios Respiratorios , Dióxido de Carbono , Inhibición Psicológica , Trastorno de Pánico , Pánico/fisiología , Análisis de Varianza , Conducta/fisiología , Miedo , Femenino , Frecuencia Cardíaca , Humanos , Trastorno de Pánico/diagnóstico , Trastorno de Pánico/psicología , Trastorno de Pánico/terapia , Inventario de Personalidad , Escalas de Valoración Psiquiátrica , Tiempo de Reacción , Respiración , Autoevaluación (Psicología) , Encuestas y Cuestionarios
3.
Metabolism ; 51(8): 1065-70, 2002 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-12145783

RESUMEN

Analogs of human insulin have been used to discriminate between responses of metabolic and mitogenic (growth-related) pathways. This study compared the stimulatory effects of human insulin (HI) and 2 analogs (X2, B-Asp(9), B-Glu(27) and H2, A-His(8),B-His(4),B-Glu(10), B-His(27)) on glucose uptake and protein synthesis in rat soleus muscle in situ. Glucose uptake, estimated by intramuscular (IM) injection of 2-deoxy[1,2-3H]glucose with or without insulin, was maximally increased at 10(-6) mol/L for HI and X2 and 10(-7) mol/L for H2. HI had a larger effect (318%) than either X2 (156%) or H2 (124%). The half-maximal effect (ED(50)) values for HI, X2, and H2 were 3.3 x10(-8) mol/L, 1.7 x 10(-7) mol/L, and 1.6 x 10(-9) mol/L, respectively. Protein synthesis, estimated by protein incorporation of [(3)H]phenylalanine injected into muscles with or without insulin, was maximally increased at 10(-5) mol/L for HI and 10(-6) for X2 and H2. HI had a larger effect in stimulating protein synthesis (34%) than either X2 (25%) or H2 (19.8%). The ED(50) values for HI, X2, and H2 were 3.0 x 10(-7) mol/L, 3.2 x 10(-7) mol/L, and 1.0 x 10(-9) mol/L, respectively. The biological potency of each analog (ED(50)insulin/ED(50)analog) showed X2 to be less potent than HI for both glucose uptake (0.2) and protein synthesis (0.9), whereas H2 is more potent than HI with ratios of 20 and 300, respectively. These data suggest that this approach for studying insulin responsiveness in a single muscle in situ may be a useful tool for investigating insulin signaling in muscle in vivo.


Asunto(s)
Desoxiglucosa/metabolismo , Insulina/farmacología , Proteínas Musculares/biosíntesis , Músculo Esquelético/efectos de los fármacos , Adipocitos/metabolismo , Animales , Transporte Biológico/efectos de los fármacos , Células CHO , Cricetinae , Femenino , Humanos , Insulina/análogos & derivados , Músculo Esquelético/metabolismo , Fenilalanina/metabolismo , Ratas , Ratas Sprague-Dawley
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