1.
Org Lett
; 26(24): 5105-5109, 2024 Jun 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38848442
RESUMEN
The asymmetric total synthesis of (+)-lemnardosinane A, a rare rearranged sesquiterpenoid, has been accomplished from (S)-carvone. Key features of the synthesis are the formation of a bicyclo[3.3.1]nonane skeleton using the intramolecular aldol reaction, the stereoselective introduction of an alkyne group, and the stereoselective formation of a tricyclic skeleton via intramolecular pinacol coupling.