Asunto(s)
Quistes/microbiología , Hepatopatías/microbiología , Fiebre Paratifoidea , Salmonella paratyphi A , Anciano , Quistes/diagnóstico por imagen , Quistes/patología , Humanos , Hepatopatías/diagnóstico por imagen , Hepatopatías/patología , Masculino , Salmonella paratyphi A/aislamiento & purificación , Tomografía Computarizada por Rayos XAsunto(s)
Síndrome de Churg-Strauss/patología , Insuficiencia Cardíaca/etiología , Herpes Simple/etiología , Perforación Intestinal/etiología , Síndrome de Churg-Strauss/complicaciones , Femenino , Insuficiencia Cardíaca/patología , Herpes Simple/patología , Humanos , Perforación Intestinal/patología , Intestino Delgado/patología , Persona de Mediana EdadAsunto(s)
Fosfatasa Alcalina/sangre , Bezafibrato/administración & dosificación , Conductos Biliares/irrigación sanguínea , Colangitis Esclerosante/complicaciones , Colangitis Esclerosante/tratamiento farmacológico , Isquemia/etiología , Biomarcadores/sangre , Colangitis Esclerosante/diagnóstico , Quimioterapia Combinada , Humanos , Isquemia/diagnóstico , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Ácido Ursodesoxicólico/administración & dosificaciónAsunto(s)
Autoanticuerpos/inmunología , Conductos Pancreáticos/inmunología , Conductos Pancreáticos/patología , Pancreatitis/etiología , Adulto , Colangiopancreatografia Retrógrada Endoscópica , Enfermedad Crónica , Femenino , Humanos , Conductos Pancreáticos/diagnóstico por imagen , Pancreatitis/inmunología , Pancreatitis/patología , Tomografía Computarizada por Rayos XRESUMEN
Amiloride is known to inhibit the taste response of vertebrates to salt by blocking the amiloride-sensitive sodium channel. In this study, we investigated electrophysiologically the effect of amiloride on the taste response of the fleshfly Boettcherisca peregrina. When 0.5 mM amiloride was included in taste solutions, the response of the salt receptor cell (salt response) to sodium chloride (NaCl) was not depressed but those of the sugar receptor cell (sugar responses) to sucrose, glucose, fructose, L-valine (L-Val) and L-phenylalanine (L-Phe) were strongly depressed. An inhibitory effect of amiloride on the concentration-response relationship for both sucrose and L-Phe was clearly revealed, but not at high concentrations of sucrose. After pretreatment of a chemosensory seta with 0.15 mM amiloride for 10 min, the salt response to NaCl was not affected. On the other hand, the sugar responses to sucrose, fructose, L-Val and L-Phe were depressed just after amiloride pretreatment. The sugar response to adenosine 5'-diphosphate (ADP) mixed with 0.5 mM amiloride was not depressed, but the response to ADP alone was depressed after amiloride pretreatment. It was therefore observed that amiloride depressed the responses to all stimulants that react with each of the receptor sites of the sugar receptor cell.