Asunto(s)
Síndrome Hemolítico-Urémico/complicaciones , Síndrome Hemolítico-Urémico/fisiopatología , Hiperglucemia/etiología , Islotes Pancreáticos/fisiopatología , Niño , Humanos , Hiperglucemia/tratamiento farmacológico , Hiperglucemia/fisiopatología , Hipoglucemiantes/uso terapéutico , Insulina/uso terapéutico , MasculinoRESUMEN
In paediatrics, the daily determination of glucose excretion is considered to be one of the major tools for the evaluation of metabolic control in diabetic children and adolescents. Large amplitudes of glucosuria from 0% to greater than 5% in this age group, however, require test methods sufficiently precise and easy to perform, the results of which may, in fact, permit to draw therapeutic consequences. Recently, a new test-tape using an enzymatic method of glucose determination has been developed Diabur-Test 5000 Boehringer Mannheim GmbH), which fulfills these requirements. In 219 urine samples, tested by a paediatric nurse practitioner, the correlation coefficient of glucose values determined by both this tape and a hexokinase reference method was found to be good: r = 0.995 (p less than 0.001). Both concerning the simplicity of performance and the precision of results, Diabur-Test 5000 proved to be superior to the well-known Clinitest-2-drop method (correlation to hexokinase method: r = 0.791 (p less than 0.001). In the hands of patients, this semiquantitative method proved to be somewhat less but still sufficiently precise to be recommended for urine glucose monitoring in diabetic children and adolescents.