RESUMEN
Serum levels of 17 beta estradiol, progesterone, prolactin and metabolites of prostaglandins E2 and F2a were investigated in 18 healthy women before and after the insertion of a Saf-T-Coil intrauterine device. The results suggest that the presence of an intrauterine device may cause hormonal changes affecting the luteal phase of the menstrual cycle.
PIP: Despite a long clinical history of use of the inert IUD as a contraceptive, the hormonal changes whch may accompany its use are not yet entirely clear. Serum levels of 17 beta estradiol, progesterone, prolactin and metabolites of prostaglandins E2 and F2a were investigated in 18 healthly women before and after the insertion of a Saf-T-Coil intrauterine device. The present data shows a 3-days shift to the right of estrogen dip and rise with clinical shortening of the luteal phase. Serum level of both steroids was found to be significantly lower in the luteal phase and at the time of menstruation. In the present study significant increase in the level of prolactin was found at the luteal phase. Besides ovarian steroids and prolactin, prostaglandins were also implicated in the contraceptive effect of the IUD. The results suggest that the presence of an IUD may cause hormonal changes affecting the luteal phase of the menstrual cycle.
Asunto(s)
Estradiol/sangre , Dispositivos Intrauterinos , Progesterona/sangre , Prolactina/sangre , Prostaglandinas E/metabolismo , Prostaglandinas F/metabolismo , Adulto , Dinoprost , Dinoprostona , Femenino , Humanos , Fase Luteínica , Hormona Luteinizante/sangre , Prostaglandinas E/sangre , Prostaglandinas F/sangreRESUMEN
The influence of fetal heart rate monitoring on endocrinological parameters (growth hormone, insulin, cortisol, dopamine, epinephrine and norepinephrine) for stress was tested in women during pregnancy and in labor. Significant increases in the levels of all hormones except dopamine were found during monitoring in women with the non-stress test in comparison with the control group. Increases of more than 50% in the level of all hormones were found during labor with or without monitoring, reflecting stress during labor. The implication of fetal heart rate monitoring on the emotional state of the pregnant woman must be taken seriously.
Asunto(s)
Corazón Fetal/fisiología , Monitoreo Fetal , Hormonas/sangre , Estrés Psicológico/sangre , Dopamina/sangre , Epinefrina/sangre , Femenino , Hormona del Crecimiento/sangre , Humanos , Hidrocortisona/sangre , Insulina/sangre , Trabajo de Parto , Norepinefrina/sangre , EmbarazoRESUMEN
The effects of various doses of indomethacin and ketoprofen as compared with placebo were examined in 100 oligospermic patients who participated in this study. It was found that the treatment increased sperm count, sperm motility, and fertilizing capacity. The radioimmunoassay examination showed an increase in plasma follicle-stimulating hormone and luteinizing hormone but a decrease in testosterone. The results show that the influence of indomethacin was better in the dose of 75 mg daily. The mechanism of those changes is not clear. Treatment should be at least 60 days.