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Both theoretical arguments and empirical evidence suggest that parasite transmission depends on host density. In helminths with complex life cycles, however, it is not clear which host, if any, is the most important. Here, the relationships between the abundance of metacercariae in second intermediate hosts, and the local density of both the first and second intermediate hosts of two trematode species, are investigated. Samples of the snail Potamopyrgus antipodarum, the amphipod Paracalliope fluviatilis and the isopod Austridotea annectens were collected from ten stations in a New Zealand lake. In the trematode Coitocaecum parvum, neither the density of the snail first intermediate host nor that of the amphipod second intermediate host correlated with infection levels in amphipods. In contrast, in the trematode Microphallus, infection levels in isopod second intermediate hosts were positively associated with isopod density and negatively associated with the density of snail first intermediate hosts. These relationships are explained by a negative correlation between snail and isopod densities, mediated in part by their different use of macrophyte beds in the lake. Overall, the results suggest that, at least for Microphallus, local infection levels depend on local intermediate host densities.

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Several brain regions associated with analogical mapping were identified using (15)O-positron emission tomography with 12 normal, high intelligence adults. Each trial presented during scanning consisted of a source picture of colored geometric shapes, a brief delay, and a target picture of colored geometric shapes. Analogous pictures did not share similar geometric shapes but did share the same system of abstract visuospatial relations. Participants judged whether each source-target pairing was analogous (analogy condition) or identical (literal condition). The results of the analogy-literal comparison showed activation in the dorsomedial frontal cortex and in the left hemisphere; the inferior, middle, and medial frontal cortices; the parietal cortex; and the superior occipital cortex. Based on these results as well as evidence from relevant cognitive neuroscience studies of reasoning and of executive working memory, we hypothesize that analogical mapping is mediated by the left prefrontal and inferior parietal cortices.

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Dentin cavities, prepared in extracted human teeth, were treated with various proprietary dentin-bonding agents and then filled with a light-cured restorative resin for posterior use. All bonding agents were either treated in accordance with the manufacturers' instructions or combined with Gluma, which is an aqueous solution of glutaraldehyde and HEMA, a hydrophilic monomer. 10 min after polymerization, the width and the extent of the marginal contraction gap was measured approximately 0.1 mm below the free surface of the filling, using a light microscope. With nearly all dentin-bonding agents, the marginal contraction gap could be significantly reduced if Gluma was used after conditioning of the dentin. The reason for this improvement may be that glutaraldehyde cross-links the collagen fibers and thereby strengthens the organic part of the hybrid layer, however, other mechanisms might also play a rôle in the improvement found.

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Study 1) The depth of proximal cavities was measured on previously taken bitewing radiographs. Study 2) By means of a scrape test, the relationship between depth of cure and irradiation distance was examined with four different curing units and two different restorative resins. Study 3) The microhardness of one of the polymerized resins was measured 0.5 mm below the free surface of the filling and then at 1.0 mm, 1.5 mm, 2.0 mm, and so forth until the resin became so soft that no hardness could be recorded. The hardness at each 0.5-mm level was recorded in relation to irradiation distance. 1) The cavity depth was most often 4-5 mm in lower premolars, 5 6 mm in upper premolars and lower molars, and 5-7 mm in upper molars. In the latter teeth, 15% of the cavities were > or =8 mm deep. 2 and 3) The depth of cure decreased moderately and in a linear manner with increasing irradiation distance. An irradiation distance of 12 mm reduced the depth of well-cured resin only by about 1 mm as compared with close contact between exit window and surface of resin.

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The aims of the study were to investigate the causes and prevalences of occupational dermatological reactions among Danish dentists. Questionnaires and telephone interviews with Danish dentists revealed that 37.8% reported skin reactions. In 27.2% of the cases the reactions were related to occupation, occurring with a point prevalence of 9.6%, and with a 1-yr period prevalence of 21.4%. The main causes were hand washing/soaps, latex gloves and (di)methacrylate-containing materials occurring at point prevalences of 7.1%, 1.3% and 1.7%, respectively. In addition, several other causes were reported, each occurring at relatively low frequency. Diagnosed allergic latex eczema was reported by 0.6%, but the frequency might be more than 2%, estimated on basis of reported symptoms. Allergic eczema caused by (di)methacrylate-containing materials was diagnosed among 0.7%, but estimated by the description of symptoms to be nearly 2%. The results urge for developing safer materials for dental use.

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The temperature rise, caused by 10 different curing units, in a prepolymerized resin specimen was examined. For all units, the temperature increase in a 60-s cycle followed a logarithmic curve, with the most effective light sources giving the highest temperature rise. In the surface layer the change of temperature ranged between 3.6 and 29.2 degrees C, and 3.2 mm below the irradiated surface between 1.5 and 12.3 degrees C. The use of a 2-mm-thick isolating layer of glass ionomer resulted in a significant reduction in the temperature increase. The correlation between the depth of cure and the temperature rise was of an exponential or power nature; i.e., a small increase of the depth of cure was followed by a disproportionately high increase in temperature.

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The light intensity from 80 different curing units was recorded on three dental radiometers. Even though the correlation between the recordings obtained with the three testers was rather high, some units were categorized as good units by one radiometer and poor ones by another. It was also found that, in some case, there was a pronounced difference between the output within the same type of new units. Cavities were made in extracted third molars, filled with a microfilled resin, irradiated for 40 s with 20 of the curing units, and the depth of cure was measured. The radiometers were not able to rank the 20 units in accordance with their depth of cure. We conclude that the three radiometers are not fully reliable. However, they may become very useful tools for monitoring the output from a curing unit if the radiometer and the unit are calibrated.

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The aim of the present study was to analyze the frequency and the severity of cuspal fracture for posterior teeth endodontically treated by 91 Danish dentists and restored with amalgam either before 1975 or after 1979. A database from a previous study was analyzed (1584 teeth with an MO, a DO, or an MOD amalgam restoration without cuspal overlays). Teeth restored before 1975 had a significantly lower frequency of cusp fracture than teeth restored after 1979. Moreover, when comparing the frequency of subcrestal fractures, that of the second group (after 1979) was more than twice as high as that of the first group (before 1975). Two factors with a bearing on these findings changed in the time period 1975-1979; the high-copper amalgams took over in Denmark, and the use of Gates-Glidden burs to achieve straight-line access to the root canal was introduced. It is suggested that the weakening of the coronal part of the root, caused by the use of Gates-Glidden burs, and the expansion and low creep of high-copper amalgams may be two of the reasons for the increased frequency and severity of cuspal fracture found in the past decade in Denmark.

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Microfilled test specimens were polymerized for 40 s with 10 different curing units. The specimens were stored for 7 days at 36 +/- 0.5 degrees C, and then the hardness of the surface was measured. The depth of cure of the 10 units was also measured, but no correlation was found between surface hardness and depth of cure. Even inferior curing units were able to polymerize the surface just as effectively as good light sources. The conclusion is that one cannot use the surface hardness of an irradiated resin to assess the quality of a curing unit.

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Dentin hypersensitivity in 112 teeth was randomly treated with Duraphat or Vitrabond. No patients were included unless they, without being asked, complained about daily pain for a long period of time caused by cold, warm, sweet, sour, touch or any combination of these five variables. Patients were excluded if the dentin hypersensitivity could have been caused by cervical abrasion/erosion lesions deeper than 1 mm, cracked-tooth syndrome, caries lesions, operative caries treatment, and/or periodontal surgery or root scaling within the last 6 months. The pain was registered on a binary scale: 1) pain before the treatment; and 2) pain/no pain after the treatment. With Duraphat, 22% of the treatments failed within 1 wk and the cumulative 1-yr success rate was 41%. With Vitrabond, 2% failed within the first week and the 1-yr success rate was 79%. The difference between the two treatments was highly significant. Patients in whom Duraphat failed were treated with Vitrabond and vice versa; the 1-yr success rate for the retreated teeth was 68% when "Duraphat-failures" were treated with Vitrabond and 42% when "Vitrabond-failures" were treated with Duraphat.

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The cumulative retention rate of a microfilled resin in non-undercut cervical abrasion/erosion lesions was studied over a 5-yr period. The enamel was etched and the dentin was pretreated with either Gluma (n = 75) or the first marketed version of Scotchbond (n = 30). The cumulative 5-yr retention rate of the Gluma fillings was 90% and that of the Scotchbond fillings 47% (the 95% confidence limits were 83-98% for Gluma fillings and 27-67% for Scotchbond fillings). The retention rate with both bonding agents was significantly higher in the maxillary arch than in the mandibular arch.

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The aim of the present study was to investigate the effect of the solubility parameter of the intermediary resin in the Gluma system on the bonding to dentin. The solubility parameter of the resins was varied between 18.8 x 10(3) and 21.1 x 10(3) J(1/2)/m3/2 by varying the composition of the resin. The efficacy of the bonding system was determined by measurements of marginal gaps formed by polymerization contraction of a restorative resin in dentin cavities treated with the bonding system. The bonding system had maximum efficacy at a solubility parameter of the intermediary resin of delta = 20.0 x 10(3) J(1/2)/m3/2. This finding corroborates a concept of bonding to dentin that involves a mechanical interlocking by interpenetrating resins.

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The marginal adaptation of a restorative resin was examined in cone-shaped cavities prepared in extracted human teeth. The use of a thin layer of a Ca(OH)2 liner in the bottom of the cavities did not influence the wall-to-wall (wtw) polymerization contraction and it did not affect the gap-reducing efficacy of a dentin-bonding agent. The wtw contraction was markedly increased when the restorative resin was applied in two layers parallel to the free surface of the cavity; the reason for this is supposed to be that the ratio between the volume of the filling (V) and the area of the cavity wall (A) is increased for the second layer compared to the V/A ratio found in cavities filled with one increment.

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The cumulative survival rate of 190 endodontically treated posterior teeth were assessed in a retrospective study; all teeth had an MO/DO or an MOD cavity restored with a composite resin without cuspal overlays after previous acid-etching of the enamel. In contrast to our previous study on endontically treated posterior teeth restored with amalgam, the survival rate of the MOD resin-restored teeth was equal to that of MO/DO teeth. Teeth restored with a light-activated resin had a much lower survival rate than teeth restored with a chemically-activated material, the cause presumably being that the light-activated resins were insufficiently irradiated. Nearly 25% of the teeth had been restored with a microfilled resin for anterior use and these teeth had a lower survival rate than had teeth restored with a macrofilled or hybrid resin. It was also found that a beveling technique did not decrease the fracture rate while the use of an intermediate layer of low-viscosity resin resulted in a significant improvement.

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The cumulative survival rate (retention of both cusps) and the fracture pattern of 1639 endodontically treated posterior teeth were assessed in a retrospective study. All teeth had an MO/DO or an MOD cavity restored with amalgam without cuspal overlays. The 20-year survival rate of teeth with an MO/DO cavity was markedly higher than that of teeth with an MOD cavity. The lowest survival rate was found for the upper premolars with an MOD cavity: 28% of these teeth fractured within 3 years after endodontic therapy, 57% were lost after 10 years, and 73% after 20 years. Generally, the cusp most prone to fracture was the lingual one, and lingual fractures caused significantly more damage to the periodontal tissues than did facial or total crown fractures. The severity of periodontal damage increased with posterior location of the tooth. By far the most serious failures, irrespective of the cavity type, were found for the upper second molar, as 10 of 29 fractures led to extraction. It is concluded that amalgam, especially in MOD cavities, is an unacceptable material for restoration of endodontically treated posterior teeth if used without cuspal overlays.

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