RESUMEN
Cognitive impairment or clinical signs of dementia in an old patient who receives digoxin, should suggest a digitalis intoxication. Symptoms can be present although a normal digoxin serum concentration. It is recommended to stop the treatment to obtain a regression of dementia symptoms.
Asunto(s)
Antiarrítmicos/efectos adversos , Trastornos del Conocimiento/inducido químicamente , Demencia/inducido químicamente , Digoxina/efectos adversos , Factores de Edad , Anciano , Anciano de 80 o más Años , Femenino , HumanosRESUMEN
INTRODUCTION: Neurosyphilis had to be evoked in the face of an atypical dementia. CASE RECORD: We describe the case of a 65-year-old man who presented with neurosyphilis suspected to precede behavioral and cognitive problems in the context of risky sexual behavior and was confirmed by serologic tests in the cerebrospinal fluid. DISCUSSION: This case proves the necessity to investigate the possibility of neurosyphilis in subjects with dementia syndrome which does not correspond to classic etiologies.
Asunto(s)
Demencia/microbiología , Neurosífilis/complicaciones , Neurosífilis/diagnóstico , Anciano , Antibacterianos/uso terapéutico , Demencia/diagnóstico , Demencia/tratamiento farmacológico , Diagnóstico Diferencial , Resultado Fatal , Humanos , Masculino , Neurosífilis/tratamiento farmacológico , Penicilina G/uso terapéuticoRESUMEN
The authors report a case of paroxysmal syncopal complete atrioventricular block due to anticholinesterase therapy occurring after the first administration. The block was reversible. It is therefore important to exclude this cause of atrioventricular block in the elderly in view of the increasing indications of this therapy.
Asunto(s)
Inhibidores de la Colinesterasa/efectos adversos , Bloqueo Cardíaco/inducido químicamente , Síncope/inducido químicamente , Anciano , Enfermedad de Alzheimer/tratamiento farmacológico , Electrocardiografía Ambulatoria , Femenino , HumanosRESUMEN
Although weight, lean mass, fat mass and muscular strength are often found to be intercorrelated, the respective role of each parameter in bone mineral density (BMD) remains unknown in older women. The aim of the present study was to investigate the relationship between body weight and composition and quadriceps strength on femoral neck and lumbar spine BMD in healthy postmenopausal women. The relationship between isokinetic quadriceps strength measured by Biodex and BMD measured by dual energy X-ray absorptiometry was studied in 56 women aged 60-81 (70.5 +/- 6.2) years in multiple regression models adjusted for age, body composition and menopausal treatment. Weight and age were associated with femoral neck BMD (33 and 10% of variance accounted for, respectively) and lumbar spine BMD (23 and 8% of its variance). When body weight and quadriceps strength were excluded from the model, lean mass and age were associated with femoral neck BMD (29 and 14% of variance explained, respectively) and lumbar spine BMD (28 and 11% of variance explained, respectively). When quadriceps strength was entered into the model, it was strongly associated with femoral neck BMD (30% of variance accounted for), in addition to lean mass (9%) and age (7%), whereas it was not associated with lumbar spine BMD. In conclusion, lean mass explains a great part of the strong association between body weight and femoral neck and lumbar spine BMD. Quadriceps strength explains a great part of the association between lean mass and BMD at the femoral neck site but not at the lumbar spine site. These results suggest a site-specific effect of muscular strength on bone and a potential role of the age-related decline of muscle strength in age-related bone loss in postmenopausal women.
Asunto(s)
Composición Corporal/fisiología , Peso Corporal/fisiología , Densidad Ósea/fisiología , Músculo Esquelético/fisiología , Factores de Edad , Anciano , Anciano de 80 o más Años , Ejercicio Físico/fisiología , Femenino , Cuello Femoral/fisiología , Humanos , Estilo de Vida , Vértebras Lumbares/fisiología , Persona de Mediana Edad , Posmenopausia/fisiología , Valores de ReferenciaAsunto(s)
Antiinfecciosos/efectos adversos , Ácido Clofíbrico/análogos & derivados , Hipolipemiantes/efectos adversos , Norfloxacino/efectos adversos , Rabdomiólisis/inducido químicamente , Síncope/inducido químicamente , Ácido Clofíbrico/efectos adversos , Quimioterapia Combinada , Femenino , Ácidos Fíbricos , Humanos , Persona de Mediana EdadRESUMEN
The effects of the ingestion of 2 whole eggs (E), 2 egg whites, 2 egg yolks (Y), or no eggs with a standard breakfast on gastric emptying, glycemic and hormonal responses have been studied in 12 healthy young males. E and Y induce a significant delay of gastric emptying, together with reduced blood glucose and insulin peaks (Y). Egg ingestion, whatever the part, increases gastric inhibitory peptide level in blood. Cholecystokinin is enhanced after E or Y ingestion. The results indicate that egg ingestion, especially yolk ingestion, may be of interest in regulating metabolic variables of glucose metabolism.
Asunto(s)
Glucemia/análisis , Colecistoquinina/sangre , Huevos , Vaciamiento Gástrico/fisiología , Polipéptido Inhibidor Gástrico/sangre , Insulina/sangre , Adolescente , Adulto , Antropometría , Clara de Huevo , Yema de Huevo , Vaciamiento Gástrico/efectos de los fármacos , Glucosa/metabolismo , Humanos , MasculinoAsunto(s)
Lesión Renal Aguda/inducido químicamente , Ácido Niflúmico/efectos adversos , Enfermedades Otorrinolaringológicas/tratamiento farmacológico , Adolescente , Infecciones Bacterianas/tratamiento farmacológico , Niño , Femenino , Humanos , Lactante , Masculino , Ácido Niflúmico/uso terapéuticoAsunto(s)
Sistemas de Registro de Reacción Adversa a Medicamentos/estadística & datos numéricos , Europa (Continente)/epidemiología , Unión Europea , Francia/epidemiología , Encuestas Epidemiológicas , Humanos , Médicos/estadística & datos numéricos , Médicos de Familia/estadística & datos numéricosRESUMEN
Glycaemic and insulinaemic index of maltitol and maltitol-containing chocolate have been determined in healthy subjects with reference to glucose and compared with those of sucrose solution and sucrose containing chocolate. All maltitol containing products (solutions and chocolate) show a reduced glycaemic index. Insulinaemic index of maltitol solutions is also low, while that of maltitol chocolate remains high.