RESUMEN
AIM: Fluoride-Amorphous Calcium Phosphate and Biomimetic Nano-Hydroxyapatite for Enamel Remineralization; An In-Vitro Study of Surface Microhardness and Composition. MATERIAL AND METHODS: Ninety-six extracted human premolars with sound buccal surface were divided using a randomization computer-generating software into four groups; Group I (control) sound untreated enamel, Group II (demineralized) demineralized to create white spot lesions, Group III (biom-n-HA) demineralized and then treated with biomimetic nanohydroxyapatite cream, and Group IV (F-ACP) demineralized and then treated using Fluoride-Amorphous Calcium Phosphate varnish. Each group was divided into two subgroups; subgroup "A" evaluated for mineral content using energy dispersive x-ray spectroscopy (EDX) and for surface microhardness using the Vickers microhardness test and Subgroup "B" evaluated for white spot lesion depth using a polarized light microscope (PLM). RESULTS: The highest microhardness (VHN) was found in the (F-ACP) group (mean=428.61±54.43) and then in the (Biom-n-HA) group (mean=408.11±70.16) followed by the (Control) group (mean=402.13±53.40) with no significant difference between them and finally in the significantly different (Demineralized) group (mean=256.99±45.83). The weight percentage of Ca (30.29±1.04 and 33.44±1.07) and Ca/P ratio (1.87±0.06 and 2.03±0.05) were significantly different between Group III and Group IV respectively. PLM measurements in Group II (198.83µm), Group III (60.17µm), and Group IV (26.33µm) were significantly different. CONCLUSIONS: Both the (Biom-n-HA) cream and the (F-ACP) varnish showed promising results for enamel remineralization. The increased enamel surface microhardness was consistent with the mineral content and the changes in the birefringence.
Asunto(s)
Fosfatos de Calcio , Esmalte Dental , Durapatita , Fluoruros , Dureza , Remineralización Dental , Humanos , Remineralización Dental/métodos , Esmalte Dental/efectos de los fármacos , Durapatita/química , Fosfatos de Calcio/farmacología , Fluoruros/química , Cariostáticos/farmacología , Desmineralización Dental , Espectrometría por Rayos X , Diente Premolar , Microscopía de Polarización , Técnicas In Vitro , Materiales Biomiméticos/química , Fluoruros Tópicos , Propiedades de SuperficieRESUMEN
This is case report of a young adult male who had developed Parkinsonism symptoms shortly after severe head injury due to accidental fall. This 45-year-old man was diagnosed as multiple hemorrhagic contusions, sub arachnoid hemorrhage and linear skull fracture. After 4 weeks of fall, he developed Parkinsonian symptoms which were relieved by anti-parkinsons disease medication. After doing thorough journal review only few reports were found regarding short term onset of Parkinsons disease after severe head injury, though most of the literatures evident of the similar symptoms after more than years after the head trauma.