RESUMEN
We describe a patient who suffered from chronic progressive granulomatous lung disease. He had no clinical or microbiological evidence of infection. After failure of treatment with interferon-gamma and trimethoprim-sulfamethoxazole, he responded dramatically to corticosteroids.
Asunto(s)
Corticoesteroides/uso terapéutico , Antivirales/farmacología , Enfermedad Granulomatosa Crónica/tratamiento farmacológico , Interferón gamma/farmacología , Enfermedades Pulmonares/congénito , Enfermedades Pulmonares/tratamiento farmacológico , Corticoesteroides/farmacología , Antiinfecciosos/farmacología , Niño , Progresión de la Enfermedad , Resistencia a Medicamentos , Enfermedad Granulomatosa Crónica/inmunología , Humanos , Enfermedades Pulmonares/patología , Masculino , Resultado del Tratamiento , Combinación Trimetoprim y Sulfametoxazol/farmacologíaRESUMEN
We report 13 patients with 16 episodes of acute lobar nephronia diagnosed in a prospective study that was conducted among 210 hospitalized children with urinary tract infection. In 30 episodes of urinary tract infection, a hypoechogenic or hyperechogenic lesion was found. Twenty patients underwent computed tomography, and in 16 of them acute lobar nephronia was diagnosed. Evolution to renal abscess occurred in 25%. Prolonged intravenous antibiotic treatment was sufficient in all cases.