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1.
PLoS One ; 19(7): e0299741, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38954730

RESUMEN

This study looked at a classical truth logic of multi-propositions that is new in some ways: [1] Alethic modalities were mixed with logical consistency and incompatibility in a single plate form, i.e., necessary consistency (NC), possible consistency (PC)/ possible incompatibility (PI) and impossible incompatibility (IPI); [2] multi-propositions were judged by individuals as either NC, PC/PI, or IPI; [3] Four quantifiers; All (∀), No (∼∀), Some (∃), and Some Not (∼∃) of four propositional modes and three shapes ([Formula: see text], ▱ and [Formula: see text]) are used to evaluate predictions; and [4] it inspired by multi-propositional of dual-process theories (DPTs) of deduction and modal syllogistic of multi-propositions, from which logicians have derived general hypotheses. HP 1- Individuals will more likely to endorse inferences as PC/PI rather than NC. HP 2: It's easier to calculate that inference has PC/ PI if it has also NC. Generally, logicians predict more endorsing PC for NC than for PI proposition. HP 3: It's easier to calculate that inference is not NC if it is also not PC. Generally, logicians predict more PI than IPI proposition endorses as NC. A modal syllogistic as a classical truth logic is presented by multi-propositions (two premises and one inference), each one from four modes has quantifiers such as universal quantifiers and existential quantifier; ∀, ∼∀, ∃, and ∼ ∃. They were evaluated by a single-mental model (Experiment I) and a multi-mental model (Experiment II). Logicians applied the immediate inference task (IIT), evaluation task (ET), and production task (PT) to evaluate three experiments. The results of the experiments suggested that students mostly endorsed PC/PI inferences over NC inferences. Even when logicians divided PC/PI separately as PC and PI, individuals endorsed PC most likely as compared to NC, and PI than IPI. Logicians also highlighted fallacies that were continuously resisted and endorsed when students were asked to judge multi-propositions that had NC. The purpose of this experimental study is to present a glimpse of students' endorsement of multi-propositions and explain that each individual has a different working memory and intelligence.

6.
EXCLI J ; 18: 1092-1093, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31938026
8.
Cureus ; 10(10): e3456, 2018 Oct 16.
Artículo en Inglés | MEDLINE | ID: mdl-30564535

RESUMEN

In recent years, transcranial magnetic stimulation has become an area of interest in the field of neurosciences due to its ability to non-invasively induce sufficient electric current to depolarize superficial axons and networks in the cortex and can be used to explore brain functioning. Evidence shows that transcranial magnetic stimulation could be used as a diagnostic and therapeutic tool for various neurological and psychiatric illnesses. The aim of this review is to introduce the basics of this technology to the readers and to bring together an overview of some of its clinical applications investigated thus far.

10.
Diabetes Technol Ther ; 18(6): 351-9, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-27258122

RESUMEN

BACKGROUND: Frequency of mealtime insulin bolusing (BOLUS) is a promising new objective assessment of adherence in youths with type 1 diabetes (T1D). As further confirmation of the validity of BOLUS, we compare the associations of glycated hemoglobin (HbA1c) values of T1D youths with the original scoring of BOLUS and two alternative scoring procedures: mean mealtime boluses within a 2-h meal window (2h-BOLUS) and total daily frequency of boluses (TOTAL-BOLUS). In addition, we assess HbA1c associations of these three procedures, including interaction terms for mealtime boluses plus correction boluses. SUBJECTS AND METHODS: Blood glucose meter data, insulin pump records, and HbA1c levels were collected from a combined clinical and research database for a random sample of 100 youths (mean age, 12.7 ± 4.6 years). Youths' pump records were scored using the published methodology and alternative procedures for evaluating insulin use. RESULTS: Youths' BOLUS, TOTAL-BOLUS, and mealtime boluses within a 2-h meal window (2h-BOLUS) scores are independently associated with youths' HbA1c level; all measures demonstrated stronger associations with youths' HbA1c than did frequency of glucose monitoring. The strongest association was between youths' BOLUS score and their HbA1c level. In multiple regression analyses, youths' BOLUS score better explains the variations in HbA1c levels than either youths' 2h-BOLUS or TOTAL-BOLUS scores. When combined with BOLUS in the same relationships, 2h-BOLUS and TOTAL-BOLUS were not found to have statistically significant coefficients. None of the bivariate relationships of HbA1c and interaction terms of mealtime and correction boluses was significant. CONCLUSIONS: The original method for calculating BOLUS appears superior to alternative scoring methods in its association with youths' HbA1c levels.


Asunto(s)
Algoritmos , Diabetes Mellitus Tipo 1/sangre , Diabetes Mellitus Tipo 1/tratamiento farmacológico , Hemoglobina Glucada/análisis , Sistemas de Infusión de Insulina , Adolescente , Glucemia/análisis , Automonitorización de la Glucosa Sanguínea , Niño , Femenino , Humanos , Hipoglucemiantes/administración & dosificación , Hipoglucemiantes/uso terapéutico , Insulina/administración & dosificación , Insulina/uso terapéutico , Masculino , Comidas
11.
Gastroenterology Res ; 8(5): 237-246, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27785303

RESUMEN

BACKGROUND: The natural course of hepatic fibrosis in HCV allograft recipients with sustained virological response (SVR) after anti-HCV therapy remains debatable. The aim of this study was to examine the progression of fibrosis in a cohort of patients who achieved SVR compared with those without treatment. METHODS: The 167 patients who met the inclusion and exclusion criteria were chosen from a transplant database. All patients were required to have histological evidence of recurrent HCV infection post-liver transplantation and a follow-up biopsy. The 140 of these patients had received anti-viral therapy. Twenty-seven patients were identified as controls and were matched with the treatment group in all respects. The patients were categorized into four groups based on treatment response: 1) no treatment (control) (n = 27); 2) non-responders (n = 81); 3) relapsers (n = 32); and 4) SVR (n = 27). The endpoint was the stage of fibrosis on the follow-up liver biopsy. RESULTS: The treated and untreated groups were similar in clinical characteristics at the time of transplantation and prior to the initiation of treatment. The 72% of the cohort showed a fibrosis progression of ≥ 1 stage; this change did not significantly differ between the patient groups. Nonetheless, the fibrosis progression rate was the highest in the untreated group and lowest in the patients who achieved SVR. A coefficient of determination was used. Improvements in fibrosis scores were found with greater treatment duration. These improvements were most evident with the achievement of SVR. CONCLUSIONS: In conclusion, SVR after anti-viral therapy for recurrent hepatitis C infection post-transplantation was associated with slower fibrosis progression and significantly improved graft survival.

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