RESUMEN

Chemotherapy-induced peripheral neuropathy (CIN) is a common toxicity of anticancer treatment and its incidence is growing. It significantly affects quality of life and is a dose-limiting factor that interferes with treatment. Its diagnosis can be established in clinical terms but some complementary tests can help when the diagnosis is difficult. There is still no proven method to prevent it that has become a standard of care in spite of the huge amount of investigation carried out in recent years. There are promising strategies that could help reduce the burden of this complication. This review will suggest an approach to the diagnosis of these disorders and provide an update on new therapies.

Asunto(s)

Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Enfermedades del Sistema Nervioso Periférico/inducido químicamente , Enfermedades del Sistema Nervioso Periférico/diagnóstico , Enfermedades del Sistema Nervioso Periférico/terapia , Animales , Suplementos Dietéticos , Humanos , Modelos Biológicos , Fármacos Neuroprotectores/uso terapéutico , Sistema Nervioso Periférico/efectos de los fármacos , Sistema Nervioso Periférico/fisiología , Enfermedades del Sistema Nervioso Periférico/prevención & control , Compuestos de Platino/efectos adversos , Compuestos de Platino/farmacología , Vitaminas/uso terapéutico