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Kardiologiia ; 27(6): 72-5, 1987 Jun.
Artículo en Ruso | MEDLINE | ID: mdl-3306092

RESUMEN

Radioimmunoassays of plasma C-peptide, and plasma and erythrocyte insulin were made in mixed venous-arterial blood specimens of normal children and those with congenital heart diseases. In all cases, insulin level was higher in erythrocytes, as compared to plasma specimens, obviously due to active insulin deposition by erythrocytes. Venous-arterial difference in insulin may be indicative of tissue insulin uptake. Respiratory and circulatory hypoxia is associated with decreased erythrocyte capacity for insulin deposition and tissue insulin uptake. It is suggested that plasma C-peptide content may be an indicator of pancreatic function.


Asunto(s)
Cardiopatías Congénitas/fisiopatología , Hipoxia/fisiopatología , Insulina/metabolismo , Páncreas/metabolismo , Transporte Biológico , Péptido C/sangre , Niño , Preescolar , Eritrocitos/metabolismo , Humanos , Hidrocortisona/sangre , Secreción de Insulina , Distribución Tisular
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