RESUMEN

Catechins and proanthocyanidins have been studied for their effect on initial stage of the protein biosynthesis. It has been found that (+)-catechin in all concentrations studied does not influence the intensity of t-RNA aminoacylation by 14C-glycine and 14C-arginine. Proanthocyanidins, namely, dimers B-3, B-6 and trimer C2 in the concentration of 10(-3) M completely inhibit the initial stage of the protein biosynthesis.

Asunto(s)

Antocianinas/farmacología , Catequina/farmacología , Hígado/efectos de los fármacos , Proantocianidinas , Biosíntesis de Proteínas , Animales , Arginina/metabolismo , Catequina/análogos & derivados , Glicina/metabolismo , Hígado/metabolismo , Masculino , Aminoacil-ARN de Transferencia/metabolismo , Ratas , Ratas Wistar