RESUMEN
The authors have seen four instances in children of osteitis due to a mycobacterium. The disease was subacute and situated in the tibia, the lumbar spine, the talus and the femur. In two cases the diagnosis was eventually mistakenly oriented towards tuberculosis or a malignant tumour. The correct diagnosis was obtained after a bone biopsy which demonstrated a granulomatous osteitis. In such cases there is an indication for a full biopsy and bacteriological examination with culture in aerobic and anaerobic media. Treatment based on pristinamycin resulted in healing.
Asunto(s)
Infecciones Bacterianas/diagnóstico , Osteítis/etiología , Niño , Preescolar , Femenino , Humanos , Masculino , Propionibacterium acnesRESUMEN
A quantitative study of the fecal flora was carried out in 21 neonates with necrotizing enterocolitis (NEC), (4 infants being born at term) and 57 control infants (30 born at term and 27 born before term). In the population as a whole Klebsiella was detected more frequently in NEC than in the controls. This was especially true in premature infants where Klebsiella was found in 65% of the affected infants versus 33% of the controls (p less than 0,05), while no Klebsiella was detected in the 4 term infants with NEC and in 87% of the term controls. These data suggest that Klebsiella could play a role in the pathogenesis of NEC, especially in the premature infant. Therefore, it seems required to avoid the artificial selection of Klebsiella in the neonate.
Asunto(s)
Bacterias Aerobias/aislamiento & purificación , Bacterias Anaerobias/aislamiento & purificación , Enterocolitis Seudomembranosa/microbiología , Heces/microbiología , Enfermedades del Prematuro/microbiología , Humanos , Recién Nacido , Estudios ProspectivosRESUMEN
The authors report a case of Corynebacterium acnes osteitis in an 11 year old girl, involving the upper of the right tibia. The lesion resembled a malignant tumour radiologically and tuberculosis histologically. Scintigraphy revealed involvement of the seventh right rib. 3 months treatment with Pristinamycin resulted in cure.
Asunto(s)
Infecciones Bacterianas , Osteomielitis/etiología , Infecciones Bacterianas/diagnóstico , Neoplasias Óseas/diagnóstico , Niño , Diagnóstico Diferencial , Femenino , Humanos , Osteomielitis/diagnóstico , Propionibacterium acnes/aislamiento & purificación , Radiografía , Cintigrafía , Costillas/diagnóstico por imagen , Tibia/diagnóstico por imagen , Tibia/patología , Tuberculosis Osteoarticular/diagnósticoAsunto(s)
Enfermedades del Ciego/congénito , Infecciones por Clostridium/congénito , Enterocolitis Seudomembranosa/congénito , Enfermedad de Hirschsprung/complicaciones , Perforación Intestinal/congénito , Clostridium perfringens/aislamiento & purificación , Hemólisis , Humanos , Recién Nacido , Masculino , Sepsis/congénitoRESUMEN
A new case report of acute pericarditis due to Rickettsia conori, the seventh to be published in the French literature, highlights the following facts:--the widespread distribution of fièvre boutonneuse, which is to be found in a wide strip around the Meditteranean basin;--the mechanism by which the pericardium is affected, which is probably auto-immune;--the criteria for the biological diagnosis of the Rickettsial diseases;--above all, the neccessity for prolonged antibiotic therapy, however apparently benign the disease may have seemed.