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1.
Radiats Biol Radioecol ; 35(6): 889-97, 1995.
Artículo en Ruso | MEDLINE | ID: mdl-8563916

RESUMEN

The model is based on classical ideas about of hemopoiesis in normal conditions and under irradiation. It consists of only two equations characterizing stem and differentiated bone marrow cell dynamics. The systemic mechanisms of hemopoiesis regulation were roughly taken into account. The formulae suitable for calculations of equilibrium cell concentrations under prolonged irradiation were derived. The model was shown to be in agreement with experimental data on hemopoietic system changes under acute and prolonged irradiation of rodents and dogs. The model is intended for describing the extent of hemopoiesis disturbance under those modes of mammalian exposure when describing of general regularities is enough.


Asunto(s)
Médula Ósea/efectos de la radiación , Modelos Biológicos , Animales , Células de la Médula Ósea , Perros , Relación Dosis-Respuesta en la Radiación , Hematopoyesis/efectos de la radiación , Células Madre Hematopoyéticas/citología , Células Madre Hematopoyéticas/efectos de la radiación , Humanos , Mamíferos , Matemática
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