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Radix Polygalae, the dried roots of Polygala tenuifolia and P. sibirica, is one of the most well-known traditional Chinese medicinal plants. It is an important medicinal plant that has been used as a sedative and to improve memory for a number of years in most of Asia. However, the in vivo constituents of the multiple constituents from Radix Polygalae remain unknown. In the current study, ultra high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and the MarkerLynxTM software combined with multiple data processing approach were used to study the constituents in vitro and in vivo. A rapid and efficient method for the characterization of multiple constituents in the herbal medicine Radix Polygalae by ultra high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry is described. In total, 35 compounds in the Radix Polygalae and 13 compounds absorbed into blood were characterized. Of the 35 compounds in vitro, ten were reported for first time. In the 13 compounds in vivo, six were prototype components and seven were metabolites were also elucidated for first time. This work narrowed the range of screening the potentially bioactive components and provided a basis for the quality control and mechanism of action.

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Abstract OBJECTIVE The aim of this study was to investigate the effect of radiology nursing intervention in abdominal examination at 3-T MRI. METHOD 60 patients with abdominal diseases were divided into two groups randomly: MR nursing intervention group and control group. All the patients underwent abdominal MR examination at 3-T. The MR nursing interventions were performed in nursing intervention group. The outcomes, including one-time success rate, the ratio of diagnosable MR images and the points of image quality, were compared between these two groups. RESULTS The one-time success rates in control group and MR nursing intervention group were 66.67% and 96.67% with significant difference ( χ2 =9.017, P<0.05). The ratios of diagnosable images in the two groups were 76.67% and 96.67% with significant difference (χ2 =5.192, P<0.05). The points of MR image quality in the two groups were 1.87±0.86 and 2.33±0.55, respectively. There was significant difference between these two groups (t=-2.508, P<0.05). CONCLUSION The effective nursing intervention can make the patients cooperation better in abdominal MR examination and improve the image quality significantly.

Resumen OBJETIVO Se objetivó investigar el efecto de la intervención de enfermería radiológica en examen abdominal de IRM 3-T. MÉTODO Sesenta pacientes con enfermedades abdominales fueron divididos aleatoriamente en dos grupos: grupo intervención de enfermería RM y grupo control. Todos fueron sometidos a examen abdominal de RM 3-T. Las intervenciones de enfermería RM se efectuaron en el grupo establecido. Los resultados, incluyendo tasa de éxito en única vez, relación de imágenes de RM diagnosticables y puntos de calidad de imagen, fueron comparadas entre ambos grupos. RESULTADOS La tasa de éxito en única vez en grupo control y grupo intervención de enfermería RM fueron de 66,67% y 96,67%, expresando diferencias significativas (χ2 =9.017, P<0.05). Los puntos de calidad de imagen de RM en ambos grupos fueron 1,87±0,86 y 2,33±0,55, respectivamente. Existió diferencia significativa entre los grupos (t=-2.508, P<0.05). CONCLUSIÓN La intervención de enfermería efectiva puede mejorar la cooperación de los pacientes en examen abdominal de RM y mejorar significativamente la calidad de imagen.

Resumo OBJETIVO O objetivo deste estudo foi investigar o resultado da intervenção de enfermagem na radiologia em exame de ressonância magnética (RM) abdominal 3 Tesla. MÉTODO 60 pacientes com patologias abdominais foram aleatoriamente divididos em dois grupos: grupo de intervenção de enfermagem em RM e grupo controle. Todos os pacientes foram submetidos ao exame de RM abdominal 3 Tesla. As intervenções de enfermagem em RM foram realizadas no grupo de intervenção de enfermagem. Os resultados foram comparados entre os dois grupos, incluindo a taxa de sucesso único, o coeficiente das imagens de RM diagnosticáveis e os pontos da qualidade de imagem. RESULTADOS As taxas de sucesso único no grupo controle e no grupo de intervenção de enfermagem em RM foram 66,67% e 96,67%, com diferença significativa de (χ2 =9,017, P<0,05). Os coeficientes das imagens diagnosticáveis nos dois grupos foram 76,67% e 96,67%, com diferença significativa de (χ2 =5,192, P<0,05). Os pontos da qualidade de imagem da RM nos dois grupos foram respectivamente 1,87±0,86 e 2,33±0,55. Houve uma diferença significativa entre estes dois grupos (t=-2,508, P<0,05). CONCLUSÃO A intervenção de enfermagem eficaz pode melhorar a cooperação dos pacientes no exame de RM abdominal e melhorar consideravelmente a qualidade da imagem.

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OBJECTIVE: The aim of this study was to investigate the effect of radiology nursing intervention in abdominal examination at 3-T MRI. METHOD: 60 patients with abdominal diseases were divided into two groups randomly: MR nursing intervention group and control group. All the patients underwent abdominal MR examination at 3-T. The MR nursing interventions were performed in nursing intervention group. The outcomes, including one-time success rate, the ratio of diagnosable MR images and the points of image quality, were compared between these two groups. RESULTS: The one-time success rates in control group and MR nursing intervention group were 66.67% and 96.67% with significant difference ( χ2 =9.017, P<0.05). The ratios of diagnosable images in the two groups were 76.67% and 96.67% with significant difference (χ2 =5.192, P<0.05). The points of MR image quality in the two groups were 1.87±0.86 and 2.33±0.55, respectively. There was significant difference between these two groups (t=-2.508, P<0.05). CONCLUSION: The effective nursing intervention can make the patients cooperation better in abdominal MR examination and improve the image quality significantly.

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