RESUMEN

1. Apparent expression of PCNA in different tumours should not be regarded as an unquestionable criterion of tumoral growth and progression but a negative result of an immunohistochemical assay for PCNA of certain human tumours is not to be taken as a proof that there is no tumoral growth whatever. 2. With results of the immunohistochemical study into the tumour for PCNA protein varying thus much, they are to be interpreted as different forms of manifestation of this protein gene abnormalities.

Asunto(s)

Carcinoma de Células Transicionales/metabolismo , Antígeno Nuclear de Célula en Proliferación/metabolismo , Neoplasias de la Vejiga Urinaria/metabolismo , Carcinoma de Células Transicionales/genética , Regulación Neoplásica de la Expresión Génica/fisiología , Humanos , Inmunohistoquímica , Pronóstico , Antígeno Nuclear de Célula en Proliferación/genética , Neoplasias de la Vejiga Urinaria/genética