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1.
Chemosphere ; 65(4): 575-82, 2006 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-16581099

RESUMEN

The effects of medetomidine, a novel antifouling candidate, on the burrowing bivalve Abra nitida were studied. The burrowing behaviour, sediment reworking activity and faeces production were assessed after 24 h exposure of A. nitida to sublethal concentrations of medetomidine. Medetomidine caused a significant decrease in the burrowing response and in the sediment reworking activity. The median effective concentrations (EC50) were 430 nM (86 microg/l) and 4.4 nM (0.9 microg/l), respectively. No effects on the faeces production were detected. Although significant effects of medetomidine on A. nitida were registered, a reversibility of the effects was observed when 24 h-exposed animals were incubated in clean seawater and sediment for 24 h. Considerations relating to the future commercialisation of medetomidine for antifouling purposes are discussed.


Asunto(s)
Conducta Animal/efectos de los fármacos , Bivalvos/efectos de los fármacos , Monitoreo del Ambiente , Medetomidina/toxicidad , Plaguicidas/toxicidad , Contaminantes Químicos del Agua/toxicidad , Animales , Bivalvos/fisiología , Heces/química , Sedimentos Geológicos/análisis
2.
Mar Pollut Bull ; 50(11): 1382-5, 2005 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-16023145

RESUMEN

The effects of the new antifouling compound zinc pyrithione (Zpt) on the embryonic development of sea urchin (Paracentrotus lividus) and mussel (Mytilus edulis) were investigated in laboratory toxicity tests. The median effective concentrations (EC50) were 7.7 nM for sea urchin embryos and 8 nM for mussel embryos. Toxic effects of Zpt on the larval growth of the sea urchin were detected at 0.5 nM. Predicted environmental concentrations of Zpt in pleasure craft harbours are higher than the predicted no effect concentrations for sea urchin and mussel embryos, indicating that Zpt may pose a threat to those species from exposure in the field.


Asunto(s)
Desarrollo Embrionario/efectos de los fármacos , Mytilus edulis/efectos de los fármacos , Compuestos Organometálicos/toxicidad , Paracentrotus/efectos de los fármacos , Piridinas/toxicidad , Análisis de Varianza , Animales , Larva/efectos de los fármacos , Larva/crecimiento & desarrollo , Mytilus edulis/embriología , Paracentrotus/embriología , Pruebas de Toxicidad
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