Asunto(s)
Adaptación Fisiológica , Antioxidantes , Sonido , Adaptación Fisiológica/efectos de los fármacos , Animales , Catalasa/sangre , Eritrocitos/enzimología , Glucosafosfato Deshidrogenasa/sangre , Glutatión Reductasa/sangre , Imidazoles/farmacología , Masculino , Ratas , Superóxido Dismutasa/sangreRESUMEN
Blood plasma of healthy persons bound 13.13 +/- 1.07 mmol/l of p-phenylene diamine (PDA), histamine pectic index constituted 33.3 +/- 2.18%. In patients with neurodermitis and eczema both these patterns were markedly reduced. Unitiol (10(-3) mol/l) increased PDA binding and histamine level in vitro. The same concentration of cystamine decreased histamine pectic index in healthy persons. Importance of protein SH-groups in binding of amines is discussed.
Asunto(s)
Aminas Biogénicas/sangre , Proteínas Sanguíneas/metabolismo , Hipersensibilidad/sangre , Cistamina/farmacología , Histamina/sangre , Humanos , Técnicas In Vitro , Fenilendiaminas/sangre , Unión Proteica , Unitiol/farmacologíaRESUMEN
Activities of amine oxidase from blood plasma and of monoamine oxidase from thrombocytes were studied in persons sensitized to yeast fungus and in patients with allergic diseases. Activity of the blood plasma amine oxidase tended to increase in sensitization and to decrease in patients with allergic dermatoses. In this group of patients activity of the thrombocyte monoamine oxidase was higher as compared with that of healthy persons.