Asunto(s)
Porocarcinoma Ecrino , Neoplasias de las Glándulas Sudoríparas , Hospitales , Humanos , EspañaAsunto(s)
Dermatosis Facial/genética , Quiste Folicular/genética , Trastornos de la Pigmentación/genética , Dermatosis Facial/cirugía , Quiste Folicular/cirugía , Humanos , Terapia por Láser/instrumentación , Láseres de Gas/uso terapéutico , Masculino , Persona de Mediana Edad , Linaje , Trastornos de la Pigmentación/cirugía , Resultado del Tratamiento , Adulto JovenRESUMEN
El hamartoma quístico foliculosebáceo (FQH) es un tumor cutáneo benigno infrecuente, compuesto de unidades foliculosebáceas asociadas con elementosmesenquimales.Presentamos el caso de una mujer de 39 años con FQH, en el que se observó la presencia de un tallo piloso en uno de los quistes.Discutimos el diagnóstico diferencial histopatológico del FQH y la relación citogenética con el tricofoliculoma (AU)
Folliculosebaceous cystic hamartoma (FQH) is a rare cutaneous benign tumour, composed of dilated folliculosebaceous units associated with mesenchymalelements.We report a 39-year-old woman with a FCH presenting a hair shaft fragment in a cyst.We discuss the histopathological differential diagnosis of FCH and the histogenetic relantionship with trichofolliculoma (AU)
Asunto(s)
Humanos , Femenino , Adulto , Hamartoma/diagnóstico , Quiste Epidérmico/diagnóstico , Quiste Folicular/diagnóstico , Foliculitis/etiologíaAsunto(s)
Eritema/tratamiento farmacológico , Inmunosupresores/uso terapéutico , Mucinosis/tratamiento farmacológico , Enfermedades de la Piel/tratamiento farmacológico , Tacrolimus/uso terapéutico , Administración Cutánea , Azul Alcián , Colorantes , Eritema/diagnóstico , Eritema/etiología , Eritema/patología , Humanos , Hipotiroidismo/complicaciones , Inmunosupresores/administración & dosificación , Masculino , Persona de Mediana Edad , Mucinosis/diagnóstico , Mucinosis/etiología , Mucinosis/patología , Enfermedades de la Piel/diagnóstico , Enfermedades de la Piel/etiología , Enfermedades de la Piel/patología , Tacrolimus/administración & dosificaciónAsunto(s)
Neoplasias Endometriales/complicaciones , Metrorragia/etiología , Neoplasias Primarias Múltiples , Pólipos/complicaciones , Anciano , Neoplasias de la Mama , Carcinoma Ductal de Mama/patología , Carcinoma Ductal de Mama/secundario , Neoplasias Endometriales/patología , Neoplasias Endometriales/secundario , Neoplasias Endometriales/cirugía , Endometrio/patología , Femenino , Humanos , Pólipos/patología , Pólipos/cirugíaRESUMEN
Ovarian ectopic pregnancy is a rare form of ectopic pregnancy, with an estimated incidence ranging from 0.5% to 3% of the extrauterine pregnancies. For a correct diagnosis of the ovarian pregnancy, the traditional criteria proposed by Spiegelberg in 1878 must be fulfilled. This forced us sometimes to reject pregnancies which, despite being initially ovarian, during its evolution the adjacent tubal structures have been affected. Currently, the ectopic pregnancies are being diagnosed more early, mainly given the echographic advances, which have lead to very conservative treatments in order to avoid a reduced fertility. However, it is many times an intraoperative diagnosis. We present four new cases of ovarian ectopic pregnancy from our casuistry of the last three years with anatomoclinical study and literature review.
Asunto(s)
Embarazo Ectópico/diagnóstico , Adulto , Femenino , Humanos , Ovariectomía , Ovario/patología , Embarazo , Embarazo Ectópico/patología , Embarazo Ectópico/cirugíaRESUMEN
We report on a patient who developed postoperative spindle cell nodule one month following TURP for prostatic adenocarcinoma. The foregoing was compared with other benign fibrous lesions from our records: one case of nodular fasciitis and one case of proliferative myositis. Although they were all well-defined and clinically distinct disease entities, a very close relationship concerning their origin was demonstrated histologically and immunohistochemically.
Asunto(s)
Neoplasias Primarias Secundarias/patología , Complicaciones Posoperatorias/patología , Sarcoma/patología , Adenocarcinoma/cirugía , Adolescente , Anciano , Fascitis/patología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Miositis/patología , Neoplasias de la Próstata/cirugíaRESUMEN
Sigma undifferentiated carcinoma of the rectum is a neuroendocrine tumor embracing less than 1% of all primary malignant epithelial tumors in this location. Recent studies have demonstrated that these tumors are biologically aggressive neoplasias with early metastatic extension. We present one case of loco-regional invasion at the time of the intervention and with distal metastasis within a period of time shorter than one year. We perform a clinical, histological and immunohistochemical study and we comment on the histogenesis of these tumors, their prognosis and treatment, stressing the need of an early diagnosis, an aggressive treatment and an adequate follow-up.
Asunto(s)
Carcinoma de Células Pequeñas/patología , Neoplasias del Recto/patología , Carcinoma de Células Pequeñas/metabolismo , Humanos , Inmunohistoquímica , Metástasis Linfática , Masculino , Persona de Mediana Edad , Cuello , Neoplasias del Recto/metabolismo , Factores de TiempoRESUMEN
A case of congenital mesoblastic nephroma in a 60-year-old female patient is described. The clinical onset was gross hematuria of 48 hours evolution and pain in the right renal fossa which irradiated to the iliac fossa of the same side. A routine pathological analysis was carried out on the surgical specimen including an extensive immunohistochemical analysis which was highly positive for keratin in the epithelial lining of the tubular and cystic structures and for desmine and vimentin in the fusocellular stroma of the tumor. The different histogenetic hypotheses are discussed. The importance of a precise anatomopathological diagnosis in order to institute adequate treatment is underscored.
Asunto(s)
Neoplasias Renales/congénito , Tumor de Wilms/congénito , Femenino , Humanos , Inmunohistoquímica , Neoplasias Renales/patología , Persona de Mediana Edad , Tumor de Wilms/patologíaRESUMEN
A case of thymic carcinosarcoma associated with a spindle cell thymoma in a 71-year-old woman is reported. Histological and immunohistochemical studies of the carcinosarcoma showed two quite different components: the sarcomatous component included cells with myoid differentiation which stained for desmin and muscle specific actin, and some isolated cells which stained positively for low molecular weight cytokeratin, while the carcinomatous component, which formed less than 10% of the tumour, showed an epithelial phenotype, being positive for low and high molecular weight cytokeratin and epithelial membrane antigen. The thymoma cells showed epithelial markers, and a few cells were also positive for desmin and muscle specific actin. The rarity of this tumour and its possible histogenesis are discussed.
Asunto(s)
Carcinosarcoma/patología , Timoma/patología , Neoplasias del Timo/patología , Anciano , Biomarcadores/análisis , Carcinosarcoma/química , Femenino , Humanos , Técnicas para Inmunoenzimas , Timoma/química , Neoplasias del Timo/químicaAsunto(s)
Leiomioma/patología , Cuello , Neoplasias de los Tejidos Blandos/patología , Adulto , Femenino , HumanosRESUMEN
We report a case of undifferentiated small cell carcinoma of the urinary bladder in a 64-year-old male patient. Microscopically the tumor was similar to the intermediate type of small cell carcinoma of the lung, with some foci of transitional papillary carcinoma, adenocarcinoma and carcinoma in situ. Small cell carcinoma is seldom encountered in the urinary bladder. It is more aggressive and must be distinguished from poorly differentiated transitional cell carcinoma.
Asunto(s)
Adenocarcinoma/patología , Carcinoma in Situ/patología , Carcinoma de Células Pequeñas/patología , Carcinoma de Células Transicionales/patología , Neoplasias Primarias Múltiples/patología , Neoplasias de la Vejiga Urinaria/patología , Adenocarcinoma/química , Adenocarcinoma/diagnóstico , Biomarcadores de Tumor/análisis , Carcinoma in Situ/química , Carcinoma in Situ/diagnóstico , Carcinoma de Células Pequeñas/química , Carcinoma de Células Pequeñas/diagnóstico , Carcinoma de Células Pequeñas/epidemiología , Carcinoma de Células Transicionales/química , Carcinoma de Células Transicionales/diagnóstico , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Proteínas de Neoplasias/análisis , Neoplasias Primarias Múltiples/química , Neoplasias de la Vejiga Urinaria/química , Neoplasias de la Vejiga Urinaria/diagnóstico , Neoplasias de la Vejiga Urinaria/epidemiologíaRESUMEN
We report a case about a neonate who died of severe subaortic stenosis due to a giant vascular dilation of the left ventricular outflow tract. We emphasize the fatal result of this benign lesion and make differential diagnosis with haemangiomas and valvular blood cysts.
Asunto(s)
Estenosis de la Válvula Aórtica/etiología , Vasos Coronarios/patología , Cardiopatías Congénitas/patología , Várices/complicaciones , Estenosis de la Válvula Aórtica/mortalidad , Estenosis de la Válvula Aórtica/patología , Electrocardiografía , Femenino , Ventrículos Cardíacos/anomalías , Humanos , Recién Nacido , Várices/patologíaRESUMEN
Six patients diagnosed as having urothelial carcinoma with varying degrees of squamous features are described. Four had pure squamous carcinoma. Two had transitional cell carcinoma (1 with squamous areas and the other had carcinoma in situ). The histological analyses of specimens were performed using immunohistochemical techniques to detect epithelial markers with low molecular weight monoclonal antibodies to cytokeratin. The tests were positive for pure squamous carcinoma and transitional cell carcinoma with squamous areas, and were negative for all areas of transitional cell carcinoma. We underscore the importance of the squamous component in the prognosis of urothelial carcinomas as well as the usefulness of this type of markers, particularly low molecular weight antibodies to cytokeratin, in differentiating squamous areas.