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1.
Cureus ; 16(5): e59482, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38826930

RESUMEN

Growth patterns and biological milestones in youth sports are key to interpreting the development of young athletes. However, there is no analysis of longitudinal meta-analysis describing the growth of young female athletes. This longitudinal meta-analysis estimated growth curves and age at peak height velocity (PHV) in young female athletes based on anthropometric data from longitudinal studies found in the literature. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, studies with repeated measurements in young female athletes were identified from searches of four databases (MEDLINE, Web of Science, SCOPUS, and SPORTDiscus) without date restrictions through August 2023. We adapted our bias assessment criteria using the Cochrane risk of bias tool for randomized controlled trials as a reference. Bayesian multilevel modeling was used to perform a longitudinal meta-analysis to extract stature growth curves and age at PHV. Fourteen studies met our eligibility criteria. Twenty-one independent samples could be included in the analysis. Conditional on the data and models, the predicted mean age at PHV for female athletes was 11.18 years (90% CI: 8.62; 12.94). When studies were aggregated by sport in the models, the models could not capture sport-specific growth curves for stature and estimate a corresponding age at PHV. We provide the first longitudinal meta-analytic summary of pubertal growth and derive age at PHV in young female athletes. The meta-analysis predicted that age at PHV occurs at similar ages to those in the general pediatric population. The data pool was limited in sports and geographic distribution, emphasizing the need to promote longitudinal research in females across different youth sports contexts.

2.
Cytokine Growth Factor Rev ; 76: 22-29, 2024 04.
Artículo en Inglés | MEDLINE | ID: mdl-38472041

RESUMEN

The bone marrow is a haven for hematopoietic and non-hematopoietic cells, creating complex micro-anatomical regions called niches. These distinct niches all participate in an intricate orchestra of cellular interactions that regulates the hematopoietic stem cell and its progenies. In this review, we provide a detailed description of the three most well-known bone marrow niches and their participation in hematopoiesis. We use pre-clinical data, including different in vitro and in vivo studies to discuss how a group of proteins called Semaphorins could potentially modulate both hematopoietic and non-hematopoietic cells, establishing links between the niches, semaphorins, and hematopoietic regulation. Thus, here we provide a deep dive into the inner functioning of the bone marrow and discuss the overarching implications that semaphorins might have on blood formation.


Asunto(s)
Médula Ósea , Semaforinas , Humanos , Diferenciación Celular/fisiología , Semaforinas/metabolismo , Nicho de Células Madre/fisiología , Células Madre Hematopoyéticas , Hematopoyesis/fisiología , Células de la Médula Ósea
4.
5.
J Sports Sci ; 41(2): 151-163, 2023 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37102423

RESUMEN

The present longitudinal meta-analysis aimed to estimate the growth curves and age at peak height velocity (PHV) in young male athletes, considering anthropometric data from available longitudinal studies. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, studies with repeated measurements in young male athletes were identified from searches across four databases (MEDLINE, SPORTDiscus, Web of Science, and SCOPUS). Estimations were based on multilevel polynomial models using a fully Bayesian framework. After a full-text screening of 317 studies meeting the eligibility criteria, 31 studies were considered. Studies were excluded mainly due to study design, repeated reporting, and incomplete reporting of the outcomes. Of the 31 studies analysed, 26 (84%) focused on young European athletes. The average age at PHV for the total sample of studies with young athletes was 13.1 years (90% credible interval: 12.9; 13.4). When considering data by sport, there was substantial variation in the age at PHV estimates (range: 12.4 to 13.5 years). As most studies in the meta-analysis focused on young European football players (52%), predictions for young athletes from other sports may be limited. The age at PHV in the available data occurred earlier than in general paediatric populations.


Asunto(s)
Fútbol , Deportes , Humanos , Masculino , Niño , Adolescente , Teorema de Bayes , Atletas , Antropometría
6.
Percept Mot Skills ; 130(2): 876-901, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36602912

RESUMEN

We examined the influence of individual and contextual characteristics on student-athlete identities and then explored identity variations across the undergraduate college years. Our main analysis relied on a quantitative study of a large sample of cross-sectional data (n = 862: females = 490, males = 372) with follow-up data for 102 participants. We also used qualitative semi-structured interviews within a small sub-sample (n = 4) who participated in international competitions to provide deeper insight into their identities across time. We used the Portuguese version of the Baller Identity Measurement Scale (BIMS) to explore student-athlete identities, and we examined the influence of sex, student-athlete status (based on institution documents), the participant's competitive level in the sport, and the student athlete's university type. We modelled response probability on BIMS items with multilevel ordinal regression in a cumulative model based on the Bayesian framework. For the follow-up in-depth qualitative interviews of four participants competing at the international level, we used thematic analysis, with two independent researchers generating thematic codes. We found a non-significant trend toward a decreased student-athlete identity across the undergraduate years. Participants' statements reflected their difficulty combining both aspects of the student-athlete identity, such that they tried to shift their identities, depending on the circumstances, while their athletic identity seemed to be privileged. Hence, participants had difficulty combining a dual academic-sport career within a context oriented toward academic achievement and transition to professional life. The higher education context was unprepared to support student-athletes toward a dual academic-sport career.


Asunto(s)
Atletas , Deportes , Masculino , Femenino , Humanos , Estudios Transversales , Teorema de Bayes , Estudiantes
7.
Front Sports Act Living ; 4: 1042494, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36704259

RESUMEN

The present study examined the influence of the specialization onset on the magnitude and patterns of changes in basketball-specific physical fitness within a competitive season and developmental fitness trends between 11 and 17 years in young basketball players. Repeated measures of 181 young basketball players (female, n = 40; male, n = 141) were examined. Anthropometry, age, estimated maturity status, and basketball-specific physical fitness (assessed with the countermovement jump, line drill, and yo-yo intermittent recovery level-1 and fitness score) were considered. Players were grouped by the onset of specialization as related to biological maturation milestones (pre-puberty, mid-puberty, and late-puberty specialization). The within-season and developmental changes in physical fitness were fitted using multilevel modeling in a fully Bayesian framework. The fitness outcomes were similar between-player and within-player changes when grouped by specialization across a season. Fitness improvements across a season were apparent for female players, while male players maintained their performance levels. There was no variation in the patterns of physical fitness development between 11 and 17 years associated with the onset of specialization. Conditional on our data and models, the assumption that early sport specialization provides a physical fitness advantage for future athletic success does not hold.

8.
PeerJ ; 9: e11863, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34395090

RESUMEN

BACKGROUND: Reliable assessment and understanding of student-athletes' motivation for dual careers are crucial to support their career development and transitions. The purpose of this research was to examine the validity and usefulness of the student-athletes' motivation toward sport and academics questionnaire (SAMSAQ-PT) in the Brazilian higher education context. Four studies were performed. METHODS: In study one, conceptually and semantic translation of the questionnaire and Bayesian exploratory factor analysis were conducted. In study two, a Bayesian confirmatory factor analysis with an independent sample was performed. In study three, Bayesian multilevel modeling was applied to examine the construct validity of the questionnaire in a cross-sectional sample. In study four, the SAMSAQ-PT sensitiveness was examined in a longitudinal sample, and the results were interpreted based on multilevel regression and poststratification. RESULTS: Altogether the results provided evidence validity and usefulness of the SAMSAQ-PT in Brazilian student-athletes. The Brazilian student-athletes' motivation scores were sensitive to the influence of sex, sport level, and type of university on career and sport motivation. SAMSAQ-PT estimate scores across an academic year showed a trend of stability in the scores, adjusting for sex, sport level, type of university, and student-athlete status. CONCLUSION: The SAMSAQ-PT proved to be a robust and valuable questionnaire, which could be used in Portuguese-speaking countries. The findings of the cross-sectional and longitudinal surveys urge to consider individual and contextual characteristics when investigating motivation of dual-career of athletes, also concerning the sex-related opportunities in university sports. Furthermore, there is a need for a call for action to promote and nurture the student-athletes motivation to remain engaged in both sports and educational commitments.

9.
PLoS One ; 16(4): e0250953, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33930069

RESUMEN

Brazil has been the benchmark for volleyball performance for at least two decades, providing a unique context to examine expertise development. This study examined the variation in body size, functional capacities, motivation for achievement, competitiveness, and deliberate practice of youth volleyball players associated with differences in biological maturity status, chronological age, and accumulated deliberate volleyball practice, adopting a Bayesian multilevel modeling approach. We considered 68 female and 94 male adolescent players (14.2 years, 90% confidence interval: 12.7 to 16.0). Players were grouped by the onset of deliberate volleyball practice as related to biologic maturation milestones [pre-puberty deliberate practice onset (12% of the sample), mid-puberty deliberate practice onset (51% of the sample), and late-puberty deliberate practice onset (37% of the sample). There was substantial variation in body dimensions and functional performance by gender. There was no variation by gender for motivation for deliberate practice and motivation for achievement and competitiveness. The young volleyball players appeared to be highly motivated and committed to deliberate practice, achievement, and competitiveness. Alignment of chronological age, biological maturation, and accumulated training experience allow more in-depth insights into young volleyball players' development, providing sounder support for coaches´ decisions.


Asunto(s)
Rendimiento Atlético/fisiología , Motivación/fisiología , Análisis Multinivel/métodos , Voleibol/estadística & datos numéricos , Logro , Adolescente , Teorema de Bayes , Tamaño Corporal/fisiología , Brasil , Femenino , Humanos , Masculino , Rendimiento Físico Funcional
10.
Artículo en Inglés | MEDLINE | ID: mdl-32521647

RESUMEN

BACKGROUND: Early sport specialization has increased its popularity mostly based on the deliberate practice theory premises. In this study, we examined the influence of the age of onset of deliberate basketball practice on body size, functional performance (countermovement jump, line drill and yo-yo intermittent recovery level 1), motivation for achievement and competitiveness, motivation for deliberate practice and sources of enjoyment among young Brazilian basketball players. In addition, we adjusted for the influence of gender, age group, maturity status and state basketball federation on the outcomes. METHODS: The sample included 120 female and 201 male adolescent basketball players aged 14.0 (1.7) years, on average. We grouped players by the age of onset of deliberate basketball practice as related to biologic maturation milestones (pre-puberty deliberate practice onset, mid-puberty deliberate practice onset and late-puberty deliberate practice onset). RESULTS: There was no substantial variation among contrasting players by the onset of deliberate practice in all of the outcomes. Adjusting for gender, male players with late-puberty deliberate practice onset had better functional performance than players with pre- and mid-puberty onset of practice. Females players with late-puberty deliberate practice onset had slightly worst functional performance than players with pre- and mid-puberty onset of practice. CONCLUSIONS: Early deliberate basketball practice does not appear to provide an advantage for the development of physiological functions. Likewise, enjoyment, motivation for deliberate practice and motivation for achievement and competition do not appear to be negatively influenced by early deliberate basketball practice. The debate about the relationship between time spent in deliberate practice and performance development in young athletes will need to emphasize the coaching pedagogical quality and the training environment and account for informal practice and deliberate play.


Asunto(s)
Rendimiento Atlético , Baloncesto , Adolescente , Teorema de Bayes , Brasil , Femenino , Humanos , Masculino , Análisis Multinivel , Rendimiento Físico Funcional , Maduración Sexual
11.
J Sports Sci ; 38(8): 873-885, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32138600

RESUMEN

The purpose of this study was to examine the variation in accumulated basketball training experience, body size, functional performance, deliberate practice motivation, achievement and competitiveness motivation and sources of enjoyment among young female basketball players, partitioning the potential variation by individuals´ biological characteristics (menarche status) and contextual characteristics (competitive age group and competitive level). We considered 114 adolescent female basketball players aged 14.3 (1.8) years. We used multilevel regression and poststratification estimations. The adolescent female basketball players selected for state-level had more accumulated experience, were taller and with better functional performance. Conditional on the data, youth female coaches tend to value (probably overvalue) size and function when selecting/promoting players, even at early age groups, likely contributing to an overrepresentation of early maturing girls in at early age groups. Players from club- and state-level were similarly highly motivated for deliberate practice and to achievement. Only for competitiveness, state-level players had higher values than club level players. The sources of enjoyment were influenced by context (competitive levels) for self-referenced competencies and others-referenced competencies. Structured programs of training and competition in youth female basketball provide a nurturing environment for the development of players´ engagement and commitment to training and excellence attainment.


Asunto(s)
Rendimiento Atlético/psicología , Baloncesto/psicología , Motivación , Placer , Adolescente , Factores de Edad , Teorema de Bayes , Estatura , Índice de Masa Corporal , Niño , Conducta Competitiva , Estudios Transversales , Femenino , Humanos , Menarquia , Acondicionamiento Físico Humano/psicología
13.
Psychol Rep ; 123(5): 1703-1723, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31810407

RESUMEN

This study examined the variation of student-athletes' identity and motivation across Portuguese and Brazilian universities, accounting for variation in gender, student-athletes' training hours per week, sports level, student-athletes status within each university, and university type. We initially established the validity of the Baller Identity Measurement Scale questionnaire and the Student-Athletes' Motivation toward Sports and Academics Questionnaire-based observations among 441 Brazilian and Portuguese student-athletes. Then, the validated version of the questionnaires was applied to a total sample of 765 student-athletes from Brazil (n= 568) and Portugal (n = 197). We further considered individual (hours of training and student-athlete status) and contextual characteristics (university type and country). Multilevel regression and poststratification were used to estimate each student-athlete identity and motivation as a function of his or her individual and contextual characteristics. Overall, the predictions showed that cultural (country), academic (type of university), and athletic (training hours) context likely have a substantial influence on student-athletes' identity and motivation.


Asunto(s)
Atletas/psicología , Motivación , Autoimagen , Estudiantes/psicología , Universidades , Brasil , Características Culturales , Femenino , Humanos , Masculino , Portugal , Encuestas y Cuestionarios
14.
Res Sports Med ; 28(1): 84-98, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-30835570

RESUMEN

Using an interdisciplinary approach, we examined the baseline variation in biological maturity status, training experience, body size, functional capacities (Line Drill test and Yo-Yo Intermittent Recovery level 1 test) and motivation for achievement, competitiveness and deliberate practice of youth basketball players according to their participation status in the sport two years after assessment. Fifty-seven players were considered (10.5 to 15.5 years). Two years later we ascertained whether players discontinued participation (dropout), or remained playing engaged within a structured basketball training program. Taller adolescent players were more likely to be selected/promoted in youth basketball regardless of their lower functional capacity. Achievement and competitiveness motivation (will to excel and competitiveness) were related to dropping out or persisting in this sample of youth basketball players. Overall, there is a need to consider the interaction between physical growth, biological maturation, functional capacities and behavioural characteristics, specifically among players on the path to sport expertise.


Asunto(s)
Rendimiento Atlético , Baloncesto , Tamaño Corporal , Motivación , Adolescente , Niño , Humanos , Masculino , Encuestas y Cuestionarios
15.
Front Med (Lausanne) ; 6: 134, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31316985

RESUMEN

The prevalence of age-related non-communicable chronic diseases has increased worldwide, being the leading causes of morbidity and death in many world regions, including in Europe. Innovative models and strategies focused on preventive care, including early identification of risk factors underlying disease onset and progression, and proper modification of lifestyle habits and behaviors, might contribute to promote quality of life, healthy living and active aging. Healthy Lifestyle Innovative Quarters for Cities and Citizens (HeaLIQs4cities) is an EIT Health-funded project aiming to engage, empower and educate citizens toward healthy lifestyles. One of the major objectives of this project was to develop a toolkit for a rapid and informal assessment of healthy lifestyles, to be used at different levels of care pathways, including in informal public environments. In this paper, we describe the methodology underlying the development of the toolkit, which resulted from the collaboration of an interdisciplinary focus group of academic experts, from medicine, sport sciences, psychology, health economics, and innovative technologies applied to health. The following eight components were included in the toolkit: (1) anthropometric assessment and cardiometabolic parameters; (2) physical activity and exercise; (3) well-being, social cohesion, and functional independence; (4) nutrition; (5) mental health; (6) smoking, drinking, and use of illicit substances; (7) sleep habits and quality; and (8) health and disease. A traffic light rating system indicating the risk score was used (low: green; moderate: yellow; and relevant: orange) for each of the 8 components, together with recommendations for the toolkit users. After completing the reduced version of the toolkit, individuals showing moderate or relevant risk in one or more of the 8 dimensions, were invited to participate in a more detailed assessment (toolkit long version), based on deeper and scientifically validated tools. The toolkit was incorporated in eVida, a web-based platform that focuses on delivering services to personalized health and well-being. The validation of the current toolkit has been applied in wide-ranging public events in three different European Regions. Large scale deployment of the toolkit is expected to profit from the Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Aging (EIP on AHA).

16.
Front Physiol ; 10: 339, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31019466

RESUMEN

Background: The interpretation of young athletes' performance during pubertal years is important to support coaches' decisions, as performance may be erroneously interpreted due to the misalignment between chronological age (CA), biological age (BA) and sport age (SA). Aim: Using a Bayesian multilevel approach, the variation in longitudinal changes in performance was examined considering the influence of CA, BA (age at menarche), SA, body size, and exposure to training among female basketball players. Method: The study had a mixed-longitudinal design. Thirty eight female basketball players (aged 13.38 ± 1.25 years at baseline) were measured three times per season. CA, BA and SA were obtained. Anthropometric and functional measures: countermovement jump, Line drill (LD), Yo-Yo (Yo-Yo IR1). Based on the sum of the z-scores, an index of overall performance was estimated. The effects of training on longitudinal changes in performance were modeled. Results: A decrease in the rate of improvements was apparent at about 14 years of age. When aligned for BA, the slowing of the rate of improvements is apparent about 2 years after menarche for LD. For countermovement jump longitudinal changes, when performance was aligned for BA improvements became linear. For Yo-Yo IR1 and performance index, both indicators showed a linear trend of improvement when aligned for CA and BA, separately. Older players showed higher rates of improvement for Yo-Yo IR1 and performance index from pre-season to end-season. When considering performance changes aligned for BA it was apparent an improvement of performance as players became biologically mature. Conclusions and Implications: The alignment of CA with BA and SA provides important information for coaches. Human growth follows a genetically determined pattern, despite variation in both tempo and timing. When the effects of maturation reach their end, all the girls went through the same process. Hence, there is no need to artificially manipulate youth competitions in order to accelerate gains that sooner or later reach their peak and tend to flat their improvement curve.

17.
J Sports Sci ; 36(7): 742-748, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28604286

RESUMEN

The interaction of multiple influences on the path to sport success is not yet fully understood by sport scientists. In this study, we examined variation in body size, functional capacities and motivation for achievement, competitiveness and deliberate practice of youth basketball players associated with differences in biological maturity status, chronological age and years of training experience. Reflecting the importance of interactive effects, we examined the relationships between the psychological variables and functional capacities. Fifty-eight male basketball players aged 9.5 to 15.5 years were considered. Variables included chronological age, estimated age at peak height velocity, stature, body mass and sitting height by anthropometry; the Work and Family Orientation and Deliberate Practice Motivation Questionnaires were also used. Finally, the Line Drill test and Yo-Yo Intermittent Recovery level 1 (Yo-Yo IR1) tests were used as functional capacities indicators for basketball. Variance components models derived from series of multilevel linear regression models revealed a substantial variation by maturity status for body size, functional capacities indicators, mastery and will to excel. The influence of estimated maturity status on mastery and will to excel was independent of age and years of experience. In contrast, no relationships were observed between psychological variables and functional capacities indicators. We conclude that growth-related changes are relevant to understanding players´ motivations for achievement, competitiveness and deliberate practice. This should be of interest to those involved in the selection and development of youth basketball players.


Asunto(s)
Rendimiento Atlético/fisiología , Rendimiento Atlético/psicología , Baloncesto/fisiología , Baloncesto/psicología , Tamaño Corporal , Conducta Competitiva/fisiología , Motivación , Adolescente , Factores de Edad , Aptitud , Niño , Humanos , Masculino , Destreza Motora/fisiología , Maduración Sexual
18.
Percept Mot Skills ; 124(5): 946-960, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28792296

RESUMEN

Youth sporting activities have been explored as a way to impact positive personal transformation and development, glaringly demonstrated by world-wide investments in public policies, programs, and projects. We studied positive effects of participation in sports on the developmental assets of 614 adolescents (13.1 ± 1.7 years) actively engaged in extracurricular sport programs targeted at socially disadvantaged youths, from five municipalities across five states of the southern, south-eastern and north-eastern regions of Brazil. Participants responded to a developmental assets questionnaire designed to capture sociodemographic and human development data. Multilevel logistic regression was used to explore associations between years of participation in sport and human development indicators, controlling for age and sex. Our results showed that the quality of the young people's support network and duration of program participation positively influenced sport participation, which, in turn, was associated with willingness to learn. A strong association was also observed between sport participation and developmental assets. Thus, we offer new evidence of a relationship between positive development and environmental factors in which individual and contextual forces can be aligned, and we provide new reference data for developing countries.


Asunto(s)
Desarrollo del Adolescente/fisiología , Desarrollo Infantil/fisiología , Deportes/fisiología , Adolescente , Brasil , Niño , Femenino , Humanos , Masculino
19.
Percept Mot Skills ; 124(3): 569-583, 2017 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-28514922

RESUMEN

The present study examined extracurricular sport participation variables and developmental context in relationship to perceived self-efficacy among underserved adolescents. Participants ( n = 821, 13.6 ± 1.5 years) completed the Youth Experience in Sport questionnaire and General Self-Efficacy Scale. We used the Human Development Index (HDI) to characterize developmental contexts. Multilevel regression models were used to explore the relative contributions of age, sex, years of participation in extracurricular sport, HDI, and perceived positive experience in sport. Our results highlight that positive experience alone and in interaction with length of participation in the program fostered perceived self-efficacy. Participants from higher HDI contexts remained longer in the program. An implication of our research is that variables linked to positive sport experiences and perceived self-efficacy can be used as markers to evaluate the outcomes and impact of sport participation programs aimed at promoting positive youth development.


Asunto(s)
Autoimagen , Autoeficacia , Deportes/psicología , Adolescente , Niño , Femenino , Humanos , Masculino , Análisis Multinivel , Encuestas y Cuestionarios
20.
Int J Sports Med ; 38(7): 551-559, 2017 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-28482363

RESUMEN

The purpose of this study was to investigate the hematological and inflammatory responses to 4 maximal high-intensity protocols, considering energy expenditure in each test. 9 healthy volunteers performed 4 high-intensity exercise tests of short [Wingate (WANT); Repeated-sprints (RSA)] and long durations [Continuous VO2 test (VCONT); intermittent VO2 test (VINT)] in a cycle-ergometer, until exhaustion. Hematological parameters and IL-6, IL-10 and creatine kinase (CK) levels were determined before (PRE), POST, 30 min, 1, 2, 12 and 24 h after the end of the protocols. Additionally, energy expenditure was determined. Leucocytes, erythrocytes and lymphocytes increased at POST and returned to PRE values at 30 min for all protocols. Lymphocytes had a second decreased at 2 h and granulocytes increased at 2 h when compared to PRE. Both variables returned to PRE values between 12-24 h into recovery. The magnitude of response for IL-6 was greater in VINT and for IL-10 in VCONT. There was no association of energy expenditure within each exercise protocol with the pattern of IL-6, IL-10 and CK responses to the exercise protocols. The present finding support that similar responses after continuous or intermittent acute protocols are observed when exercises are performed to volitional failure, regardless of the duration and mode of exercise.


Asunto(s)
Metabolismo Energético , Ejercicio Físico/fisiología , Sistema Inmunológico/fisiología , Adulto , Creatina Quinasa/sangre , Eritrocitos/citología , Prueba de Esfuerzo , Femenino , Granulocitos/citología , Humanos , Inflamación , Interleucina-10/sangre , Interleucina-6/sangre , Linfocitos/citología , Masculino
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