RESUMEN
OBJECTIVE: to describe the occurrence of cases of congenital heart disease in infants under one year recorded in health information systems of Rio de Janeiro State, from 2006 to 2010. METHODS: descriptive study with data from the Information System on Live Births (Sinasc), Hospital Information System of the Brazilian National Health System (SIH/SUS) and Mortality Information System (SIM). RESULTS: a total of 345 records were found on Sinasc, there were 1,089 hospitalized children (SIH/SUS) and 1,121 deaths (SIM) of children under one year of age whose underlying cause was congenital heart disease; the prevalence of congenital heart disease was 3.18/10,000 live births; heart diseases were the main causes of death in the group of congenital malformations, with a mortality coefficient of 1.03/1,000 live births. CONCLUSION: there was underreporting of cases of congenital heart disease on Sinasc, demonstrating the difficulty of early diagnosis.
Asunto(s)
Causas de Muerte , Cardiopatías Congénitas/epidemiología , Hospitalización/estadística & datos numéricos , Certificado de Nacimiento , Brasil/epidemiología , Certificado de Defunción , Femenino , Cardiopatías Congénitas/mortalidad , Sistemas de Información en Hospital , Humanos , Lactante , Recién Nacido , Sistemas de Información , Masculino , PrevalenciaRESUMEN
BACKGROUND: Cervical cancer is the third most common cancer in Brazil and has a high potential for prevention and cure. The prevalence of invasive and preinvasive disease in women with cytological diagnosis of high-grade lesion - cannot exclude microinvasion (HSIL-micro) is not known. METHODS: This cross-sectional study used a cytology lab database to identify women with HSIL-micro and HSIL referred to two colposcopic units from June 2006 to December 2012. For each woman with HSIL-micro, four women with cytologic diagnosis of HSIL who met the inclusion criteria were identified. Data were obtained from review of medical records. RESULTS: Forty-seven patients with report of HSIL-micro and 188 patients with report of HSIL were included. The final diagnoses revealed a frequency of preinvasive lesions of 31.9 % (15/47) and 59.6 % (112/188) in patients with HSIL-micro and HSIL, respectively, while the frequency of invasive disease was 63.8 % (30/47) and 11.7 % (22/188), respectively. The HSIL-micro group showed prevalence of preinvasive or invasive disease 6.5 times greater (95 % CI = 1.6-5.7) and, for invasive disease, 2.4 times greater (95 % CI = 1.7-3.6) than the HSIL group. CONCLUSION: Higher risk of preinvasive and invasive lesions in women with cytologic diagnosis of HSIL-micro reinforces recommendations for immediate investigation.
Asunto(s)
Neoplasias del Cuello Uterino/diagnóstico , Adulto , Brasil/epidemiología , Biología Celular , Colposcopía/estadística & datos numéricos , Estudios Transversales , Femenino , Humanos , Persona de Mediana Edad , Embarazo , Prevalencia , Neoplasias del Cuello Uterino/epidemiología , Neoplasias del Cuello Uterino/patología , Frotis Vaginal/estadística & datos numéricosRESUMEN
OBJECTIVE: To evaluate the prevalence of bone mineral disease among adolescents with cystic fibrosis and to relate the findings with the variables studied. METHODS: The study enrolled 37 adolescents who were assessed for: nutritional status according to height/age and body mass/age ratios; bone mineral density of the lumbar spine and entire body by densitometry with dual emission X-ray; daily dietary intake according to a 3-day dietary recall; and pulmonary function by the forced expiratory volume in one second test. RESULTS: Mean age was 13.2 (+/-2.8) years. Nutritional status was adequate in 70.3 and 75.7% of patients according to the height/age and body mass/age indices, respectively; 54.1% of the patients exhibited reduced lumbar spine bone mineral density and 32.5% for the whole body. There was a positive correlation between bone mineral density and body mass index (p = 0.04). Lung disease and pancreatic insufficiency exhibited a correlation with altered bone mineral density. The dietary recall revealed adequate percentages of calcium, phosphorous and calories, according to the nutritional recommendations laid out in the European Cystic Fibrosis Consensus. The multivariate analysis indicated that these variables were not statistically significant. CONCLUSIONS: There is a high prevalence of bone mineral disease among adolescents. Good nutritional status, pancreatic enzyme replacement and control of lung disease may have a protective effect on bone mass.