RESUMEN
Resumo O estudo investiga como a velhice era representada em uma modernidade brasileira na década de 1930. Foi realizada uma pesquisa histórica que teve como fontes periódicos médicos e, principalmente, jornais e revistas das cidades de São Paulo e do Rio de Janeiro. A pesquisa demonstrou que as particularidades e contradições de uma modernidade brasileira contribuíram para uma variedade de representações da velhice. A análise do corpo documental impediu uma descrição homogênea da velhice, mas atestou considerável aumento do poder dos saberes científico e médico sobre os comportamentos considerados adequados em relação aos corpos na década de 1930.
Abstract The way old age was depicted during the 1930s, in Brazilian modernity, is investigated. A historical study was conducted using as its sources newspapers and magazines published in São Paulo and Rio de Janeiro, as well as medical periodicals. It showed that the particularities and contradictions of Brazilian modernity contributed to a variety of representations of old age. The analysis of the documentary corpus failed to reveal a homogenous description of old age, but identified a considerable increase in the power of scientific and medical knowledge about behaviors considered adequate with regard to bodies in the 1930s.
Asunto(s)
Humanos , Masculino , Femenino , Historia del Siglo XX , Anciano/psicología , Religión y Medicina , Estereotipo , Cirugía Plástica/historia , Brasil , Envejecimiento/psicología , MuerteRESUMEN
Este artículo presenta un análisis desde el punto de vista bibliográfico de marcadores y biomarcadores de la enfermedad de Alzheimer (EA). Las metodologías usadas fueron los marcadores de imágenes (Resonancia Magnética y Tomografía por emisión de positrones) y biomarcadores de la proteína BA42, de la proteína Tau y de la Apoliproteína E (ALPE). De esta manera, son de importancia los niveles de BA42 disminuidos, la Tau incrementada, los polimorfismos de ALPE y las alteraciones constatadas en los marcadores de imagen, como factores de riesgo esenciales para el desarrollo de la EA. Se realiza una revisión de la literatura con respecto a los hallazgos clínicos de esta enfermedad.
This article presents a bibliographical analysis of markers and biomarkers of Alzheimer's disease (AD). The methodologies used were the imaging markers (Magnetic Resonance and Positron Emission Tomography) and biomarkers of the BA42 protein, Tau protein and Apoliprotein E (ALPE). Thus, decreased levels of BA42, increased Tau, ALPE polymorphisms, and alterations in imaging markers are important as risk factors for the development of AD. A review of the literature is made regarding the clinical findings of this disease.
Asunto(s)
Humanos , Enfermedad de Alzheimer/diagnóstico por imagen , Enfermedad de Alzheimer/metabolismo , Biomarcadores/metabolismo , Enfermedad de Alzheimer/fisiopatología , Apolipoproteínas E/metabolismo , Imagen por Resonancia Magnética , Tomografía de Emisión de Positrones , Proteínas tau/metabolismoRESUMEN
Despite the growing evidence of poor psychosocial adjustment, at present there is no formal method of assessment of social adjustment in patients with temporal lobe epilepsy (TLE). First, we assessed social adjustment in patients with TLE using a self-report questionnaire and compared the results with those from quality-of-life (QOL) scales. Second, we verified the influence of cognitive performance and clinical variables of epilepsy on social adjustment and QOL. We evaluated 35 people with TLE and 38 healthy controls. Patients had worse social adjustment, and it was correlated with worse perception of cognitive function. Attention and verbal memory dysfunctions were negatively correlated with social adjustment. However, there was no significant correlation between cognitive performance and QOL. Regarding clinical variables, persons with left TLE showed worse social adjustment and patients with frequent seizures showed worse QOL. These findings indicate the relevance of evaluating social adjustment and emphasize the importance of cognitive rehabilitation to improved social adjustment.
Asunto(s)
Epilepsia del Lóbulo Temporal/psicología , Calidad de Vida , Ajuste Social , Adaptación Psicológica , Análisis de Varianza , Femenino , Humanos , Masculino , Pruebas Neuropsicológicas , Estadísticas no Paramétricas , Encuestas y CuestionariosRESUMEN
É apresentada uma revisäo sobre sudorese gustatória (síndrome de Frey) após cirurgias sobre a glândula parótida. O histórico, a fisiopatologia, o diagnóstico, incluindo uma nova modalidade terapêutica usando toxina botulínica, säo abrangentemente discutidos.
Asunto(s)
Sudoración Gustativa , Sudoración Gustativa/historia , Sudoración Gustativa/fisiopatología , Sudoración Gustativa/terapia , Toxinas Botulínicas/uso terapéuticoRESUMEN
PURPOSE--To compare the prevalence of primary dyslipidemia in 2 groups, based on NCEP guidelines: a) first degree relatives of revascularized patients and b) hospital employees without family history of coronary heart disease (CHD). METHODS--1162 subjects aged over 20 years, were divided in two groups: G Fam consisted of 312 women and 221 men, mean age 30.8 years, siblings, brothers or sisters of revascularized patients (under 55 years old); G Serv consisted of 425 women and 204 men, mean age 30.7 years, all of them being healthy employees of Hospital das Clínicas (Clinics Hospital) with no family history of CHD. There were performed clinical, electrocardiographic and laboratory tests (total blood cholesterol--CT, triglycerides--TG and HDL cholesterol--HDL-C): and VLDL-C and LDL-C values were calculated according to Friedwald, besides CT/HDL-C and LDL-C/HDL-C ratios. Based on NCEP guidelines, the frequencies on values ranges for each parameter were determined. RESULTS--G Fam group showed a higher incidence of women and men with CT and LDL-C levels above 240 mg/dl and 160 mg/dl, respectively; CT/HDL-C and LDL-C/HDL-C values over 5.0 and 3.5, respectively, were seen more often in G Fam group. There were no significant differences on HDL-C and TG. About 35% of men and women in G Serv group showed CT levels higher than 200 mg/dl. CONCLUSION--First-degree relatives, aged over 20 years, from revascularized patients under 55 years old, showed more often lipid levels above those established by NCEP. In accordance to them, 62% of men and 28% of women of this group should undergo to LDL-C analysis, as well as 35% of men and 28% of women in teh G Serv group. It is called the attention for the importance of cholesterolemia evaluation in high risk groups for CHD.