RESUMEN
The radiological contamination of Wroclaw Region after Czernobyl accident was evaluated as moderate. In the frame of Research Programme MZ-XVII 4310 persons (2012 men and 2298 women) were randomly selected and investigated. Among them were 1525 children up to 16 years old. 925 children and 854 adults took potassium iodide; only minority in April but majority between May 1st and May 5th. Side effects was rare phenomenon seen in about 5% of those who ingested potassium iodide and in majority of cases was very mild (with rash and vomiting as most common clinical symptoms). Only 13 persons with side effects have visited physicians. Among 955 women aged 19-40 years 71 were pregnant in May 1986. 55 of them delivered on time, 3 before time. Average health state of newborns was 9.1 according to Apgar scale. 10 women have had spontaneous abortion and 3 decided to terminate pregnancy in first 6 weeks. The physical examination revealed the presence of diffuse goiter in 384 persons and of nodular goiter in 23 persons. In majority of cases the goiter was small, OB or I. according to WHO classification.
Asunto(s)
Contaminantes Radiactivos del Aire/efectos adversos , Yoduro de Potasio/uso terapéutico , Centrales Eléctricas , Liberación de Radiactividad Peligrosa , Enfermedades de la Tiroides/prevención & control , Adolescente , Adulto , Puntaje de Apgar , Niño , Preescolar , Femenino , Bocio/epidemiología , Bocio/etiología , Humanos , Incidencia , Recién Nacido , Masculino , Persona de Mediana Edad , Polonia/epidemiología , Yoduro de Potasio/efectos adversos , Embarazo , Enfermedades de la Tiroides/etiología , UcraniaRESUMEN
The level of several biochemical hematological characteristics was determined--using colorimetric methods--in a group of 111 twins, aged 16-22 years. Significant variance differences between MZ and DZ twin pairs were observed in metabolites and serum enzyme levels. The intrapair differences of the variance of ions and protein levels were comparable in MZ and DZ twins. The validity of quantitative determination of heterability of biochemical characteristics is discussed.
Asunto(s)
Análisis Químico de la Sangre , Gemelos Dicigóticos , Gemelos Monocigóticos , Gemelos , Adolescente , Adulto , Femenino , Humanos , Masculino , Fenotipo , Factores SexualesAsunto(s)
Diabetes Mellitus/epidemiología , Adolescente , Adulto , Factores de Edad , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Proyectos Piloto , Polonia , Factores Sexuales , Población UrbanaAsunto(s)
Campos de Concentración , Morbilidad , Prisiones , Adulto , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , PoloniaAsunto(s)
Agricultura , Estado de Salud , Salud , Salud Urbana , Contaminantes del Agua/análisis , Abastecimiento de Agua/análisis , Adulto , Femenino , Humanos , Masculino , Morbilidad , Polonia , Microbiología del AguaRESUMEN
Human prostatic acid phosphatase I, a glycoprotein, has been analyzed with respect to its quantiative carbohydrate composition and its fluorescence, optical rotatory and circular dichroic spectra. The protein of 89 000 molecular weight has 38 to 41 carbohydrate residues attached, of which 3 residues are fucose, 4 are galactose, 11 mannose, 15 glucosamine and there are 7 to 8 residues of sialic acid. The native glycoprotein contains about 30% alpha-helix as estimated from the rotational and dichroic spectra. Upon removal of sialic acid by neuraminidase treatment, there is a small increase in this value, while the fluorescence intensity at he emission maximum (357 nm) is distinctly increased. These effects suggest that an interaction exists of the sialic acid group with parts of the native protein. Allowance is made for the contribution of the carbohydrate components in interpreting the spectra in structural terms.