RESUMEN

The inhibitory effect of flavopentin was shown on the models of infectious and oncogenic viruses. Flavopentin is a polyenic antibiotic belonging to pentaenes. The characteristic features of the polyene interaction with the plasma membrane of the host cell were defined with the use of the luminescence analysis, when the antibiotic was applied with the therapeutic or prophylactic purposes in experimental influenzal infection.

Asunto(s)

Antibacterianos/farmacología , Antivirales/farmacología , Animales , Antibacterianos/análisis , Antivirales/análisis , Virus del Sarcoma Aviar/efectos de los fármacos , Embrión de Pollo , Virus de la Influenza A/efectos de los fármacos , Polienos/análisis , Polienos/farmacología , Espectrometría de Fluorescencia , Virus Vaccinia/efectos de los fármacos , Cultivo de Virus

Asunto(s)

Proteínas Sanguíneas/análisis , Linfoma no Hodgkin/sangre , Animales , Trasplante de Neoplasias , Ratas , Sarcoma Experimental/sangre , Espectrometría de Fluorescencia