Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 31
Filtrar
1.
Rev. cuba. ortop. traumatol ; 35(2): e344, 2021. ilus, tab
Artículo en Español | LILACS, CUMED | ID: biblio-1341469

RESUMEN

Introducción: La luxación de la prótesis total de cadera puede afectar los resultados del implante, la calidad de vida del paciente, y el costo del proceso. Su etiología es multifactorial. Objetivos: Identificar posibles factores de riesgo relacionados con la aparición de luxación en prótesis total de cadera en una serie de casos. Métodos: En una serie de 2732 prótesis total de cadera, en la que hubo 92 luxaciones (3,4 por ciento), se compararon factores relacionados con el paciente, el implante, y la técnica quirúrgica uilizada en el Hospital La Paz-IDIPaz de Madrid entre los años 2000 y 2016. Se utilizó el análisis de regresión para la significación de dichos factores. Resultados: De las 92 luxaciones, 62 fueron tratadas de manera conservadora (67,4 por ciento) y 30 pacientes precisaron de cirugía de revisión (32,6 por ciento). El estudio multivariado mostró significación estadística en los siguientes factores de riesgo: estado de la columna lumbar (p < 0,001), y una pobre reconstrucción del centro de rotación de la cadera (p= 0,035), y cúpulas posicionadas fuera de las ventanas de Lewinnek (p < 0,001) y del mecanismo abductor (p < 0,001) en relación con la técnica quirúrgica. No hubo factores significativos en relación con el tipo de implante, diámetro de la cabeza femoral o par de fricción. Conclusiones: La patología lumbar aumenta el riesgo de luxación en la prótesis total de cadera. Una adecuada reconstrucción de la cadera, que incluya la posición de la cúpula y el centro de rotación de la cadera, así como del mecanismo abductor ayudaría a mejorar la tasa de inestabilidad(AU)


Introduction: The dislocation of the total hip replacement can affect the results of the implant, the quality of life of the patient, and the cost of the process. Its etiology is multifactorial. Objectives: To identify possible risk factors related to the appearance of dislocation in total hip replacement in a series of cases. Methods: In a series of 2732 total hip prostheses, in which there were 92 dislocations (3.4percent), factors related to the patient, the implant, and the surgical technique used at La Paz-IDIPaz Hospital in Madrid were compared, from 2000 to 2016. Regression analysis was used for the significance of these factors. Results: Out of 92 dislocations, 62 were treated conservatively (67.4 percent) and 30 patients required revision surgery (32.6 pecent). The multivariate study showed statistical significance in the following risk factors: state of the lumbar spine (p <0.001), and poor reconstruction of the center of rotation of the hip (p = 0.035), and domes positioned outside Lewinnek windows (p <0.001) and the abductor mechanism (p <0.001) in relation to the surgical technique. There were no significant factors in relation to the type of implant, diameter of the femoral head or friction torque. Conclusions: Lumbar pathology increases the risk of dislocation in total hip replacement. Proper hip reconstruction, including the position of the dome and the center of rotation of the hip, as well as the abductor mechanism, would help to improve the rate of instability(AU)


Asunto(s)
Humanos , Masculino , Femenino , Factores de Riesgo , Artroplastia de Reemplazo de Cadera/métodos , Luxaciones Articulares/etiología
2.
Bone Joint J ; 103-B(3): 492-499, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33641418

RESUMEN

AIMS: Bone stock restoration of acetabular bone defects using impaction bone grafting (IBG) in total hip arthroplasty may facilitate future re-revision in the event of failure of the reconstruction. We hypothesized that the acetabular bone defect during re-revision surgery after IBG was smaller than during the previous revision surgery. The clinical and radiological results of re-revisions with repeated use of IBG were also analyzed. METHODS: In a series of 382 acetabular revisions using IBG and a cemented component, 45 hips (45 patients) that had failed due to aseptic loosening were re-revised between 1992 and 2016. Acetabular bone defects graded according to Paprosky during the first and the re-revision surgery were compared. Clinical and radiological findings were analyzed over time. Survival analysis was performed using a competing risk analysis. RESULTS: Intraoperative bone defect during the initial revision included 19 Paprosky type IIIA and 29 Paprosky type IIIB hips; at re-revision, seven hips were Paprosky type II, 27 type IIIA and 11 were type IIIB (p = 0.020). The mean preoperative Harris Hip Score was 45.4 (SD 6.4), becoming 80.7 (SD 12.7) at the final follow-up. In all, 12 hips showed radiological migration of the acetabular component, and three required further revision surgery. The nine-year cumulative failure incidence (nine patients at risk) of the acetabular component for further revision surgery was 9.6% (95% confidence interval (CI) 2.9 to 21.0) for any cause, and 7.5% (95% CI 1.9 to 18.5) for aseptic loosening. Hips with a greater hip height had a higher risk for radiological migration (odds ratio 1.09, 95% CI 1.02 to 1.17; p = 0.008). CONCLUSION: Bone stock restoration can be obtained using IBG in revision hip surgery. This technique is also useful in re-revision surgery; however, a better surgical technique including a closer distance to hip rotation centre could decrease the risk of radiological migration of the acetabular component. A longer follow-up is required to assess potential fixation deterioration. Cite this article: Bone Joint J 2021;103-B(3):492-499.


Asunto(s)
Acetábulo/cirugía , Artroplastia de Reemplazo de Cadera , Trasplante Óseo/métodos , Complicaciones Posoperatorias/cirugía , Reoperación/métodos , Anciano , Anciano de 80 o más Años , Femenino , Prótesis de Cadera , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Falla de Prótesis , España
3.
Sci Rep ; 11(1): 576, 2021 01 12.
Artículo en Inglés | MEDLINE | ID: mdl-33436773

RESUMEN

The biological mechanisms involved in aseptic loosening include inflammation-associated and bone resorption-associated processes. Coordinated cellular actions result in biochemical imbalances with devastating consequences for the joint. Given that this condition is not known for showing systemic signs, we investigated whether circulating levels of inflammation-related proteins are altered in patients with aseptic loosening. Our study included 37 patients who underwent revision surgery due to hip osteolysis and aseptic loosening and 31 patients who underwent primary total hip arthroplasty. Using antibody arrays, we evaluated the serum levels of 320 proteins in four patients from each group. The results showed differences in insulin-like growth factor-binding protein 1 (IGFBP-1) concentrations, which we then quantified using enzyme-linked immunosorbent assay tests in all study patients. The results confirmed that serum IGFBP-1 concentrations were higher in the revision surgery patients than in the hip arthroplasty patients. In vitro studies showed that exposure of human osteoblasts to titanium particles induced an IGFBP-1 release that further increased when exposure to particles was performed in media conditioned by human M1 macrophages. These findings suggest that elevated serum IGFBP-1 levels in patients with aseptic loosening can arise from increased local IGFBP-1 production in the inflammatory environment of the periprosthetic bed.


Asunto(s)
Artroplastia de Reemplazo de Cadera/efectos adversos , Prótesis de Cadera/efectos adversos , Proteína 1 de Unión a Factor de Crecimiento Similar a la Insulina/sangre , Falla de Prótesis/efectos adversos , Falla de Prótesis/etiología , Anciano , Ensayo de Inmunoadsorción Enzimática , Femenino , Humanos , Técnicas In Vitro , Proteína 1 de Unión a Factor de Crecimiento Similar a la Insulina/metabolismo , Macrófagos , Masculino , Osteoblastos/metabolismo , Osteólisis/etiología , Reoperación , Titanio/efectos adversos
4.
Orthop Traumatol Surg Res ; 107(1): 102763, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33321234

RESUMEN

INTRODUCTION: Underlying diseases, bone deformities and polyethylene wear affect outcome in young patients undergoing total hip arthroplasty (THA). These issues are not widely confirmed for ceramic - on-ceramic THA, particularly regarding cup fixation. Therefore, we did a retrospective long-term investigation on a large population of cementless ceramic-on-ceramic THA in patients aged 40 years or younger aiming to analyze: 1) the complication rate; 2) clinical results; and 3) survival for cup loosening with regard to their preoperative conditions. HYPOTHESIS: Cup loosening could be related to preoperative diagnosis in young patients with a cementless ceramic-on-ceramic THA. PATIENTS AND METHODS: Two hundred and seven hips in 171 patients (97 men and 74 women) underwent a cementless ceramic-on-ceramic THA at a mean age of 31.6±6.8 years. The most frequent diagnoses were avascular necrosis (AVN) of the femoral head (74 hips), pediatric hip diseases (35 hips), severe congenital hip dysplasia (CHD) (31 hips), juvenile rheumatoid arthritis (30 hips) and mild CHD (26 hips). The prosthesis included a press-fit metal backed cup with a hydroxyapatite coating and a macrotexture surface on either the equatorial region (93 cups) or the entire surface of the shell (114 cups). Ceramics were made of pure alumina and had a femoral head size of 28 (60 hips) or 32mm (147 hips). In all cases same the straight cementless tapered stem was inserted. RESULTS: There were three early dislocations, one requiring cup revision No hip was revised due to infection, ceramic fracture, or femoral component loosening. Eight cups were revised for aseptic loosening (3,8%). The mean preoperative Harris Hip score was 52.8±6.2 and 93.4±6.9 at the end of follow-up. It was better in AVN (95.7±2.3) and worst in severe CHD (88.8±11.8) (p=0.001). If the end-point was cup aseptic loosening, the survival rate at 17 years was 95.1% (95% CI: 91.3-98.9), 100% for AVN and post-traumatic arthritis, and 86.8% (95% CI: 74.9-98.7) for severe CHD. CONCLUSIONS: Despite diagnoses frequently causing technical difficulties at the surgery, outcome of cementless ceramic-on-ceramic THA in patients under the age of 40 years is satisfactory over ten years of follow up. Cup aseptic loosening was the main cause of failure and appears more related to the initial hip diseases than the age of the patient. LEVEL OF EVIDENCE: III; retrospective comparative study.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Prótesis de Cadera , Adulto , Cerámica , Niño , Femenino , Cabeza Femoral , Estudios de Seguimiento , Humanos , Masculino , Diseño de Prótesis , Falla de Prótesis , Reoperación , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
5.
Hip Int ; 30(3): 339-346, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-30912452

RESUMEN

PURPOSE: To determine if initial treatment affects the outcome of total hip arthroplasty (THA) after acetabular fracture. METHODS: 49 patients (49 hips) initially treated non-operatively followed some months later by THA in conjunction with acetabular reconstruction (Group 1) and 29 patients (29 hips) who had undergone THA after a previous osteosynthesis (Group 2) were assessed. The mean follow-up was 11.7 (range 5-23) years. RESULTS: 3 acetabular components were revised for aseptic loosening in Group 1 and 2 in Group 2. The survival rate for cup loosening at 16 years was 90.6% (95% confidence interval [CI], 78.1-100) for Group 1 and 94.1% (95% CI, 86.5-100) for Group 2 (p = 0.76). There were 2 sciatic palsies in Group 2 after osteosynthesis. The mean preoperative clinical score and postoperative range of mobility were better in Group 1. There were more heterotopic ossifications in Group 2. CONCLUSION: Despite the good results found in both groups, THA after previous osteosynthesis for acetabular fractures had more complications than a primary THA in conjunction with acetabular reconstruction.


Asunto(s)
Acetábulo/diagnóstico por imagen , Artroplastia de Reemplazo de Cadera/métodos , Predicción , Fijación Interna de Fracturas/métodos , Fracturas de Cadera/cirugía , Prótesis de Cadera , Radiografía/métodos , Acetábulo/lesiones , Acetábulo/cirugía , Estudios de Seguimiento , Fracturas de Cadera/diagnóstico , Fracturas de Cadera/fisiopatología , Humanos , Periodo Posoperatorio , Rango del Movimiento Articular , Resultado del Tratamiento
6.
Open Orthop J ; 12: 125-133, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29785222

RESUMEN

BACKGROUND: Bone remodelling with lateral femoral cortex thinning is a major concern after extensively porous-coated long-stem in revision surgery. Extensive hydroxyapatite coated long-stems were introduced to improve osseointegration, but bone remodelling changes have not been quantified. OBJECTIVE: The question of whether bone remodelling changes from extensive hydroxyapatite-coated long stems influence the durability of femoral revision, clinical outcome is assessed in follow-up radiographs. METHODS: Uncemented straight monoblock hydroxyapatite-coated long-stems used in revision hip surgery for aseptic loosening were assessed in a consecutive series of 64 hips (60 patients). Mean follow-up was 8.6 years and the mean age at surgery was 70 years (27-91). The pre-operative bone defect was classified according to Paprosky. Cortical struts were not used in this series. Cortical index and femoral cortical width were measured at three different levels at different periods. RESULTS: Four patients with pain under level 4 due to stem loosening needed an exchange surgery of their femoral component, but two patients rejected re-surgery. The cumulative probability of not having aseptic loosening was 91.2% (95% confidence interval 73.5-96.9) at 10 years according to Kaplan and Meier. Twenty-seven of 35 osteolytic lesions had disappeared or decreased at the last follow-up. The thickness of the lateral and medial cortex increased over the course of the study at different levels. Increases of femoral cortex thickness were greater in men and in cases with mild bone defects. CONCLUSION: Although clinical outcome of the hydroxyapatite-coated long stem in revision surgery is good but not outstanding, most osteolytic lesions heal and the femoral cortex thickness increases at different levels.

7.
J Bone Joint Surg Am ; 99(22): 1927-1931, 2017 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-29135666

RESUMEN

We previously reported the 10 to 13-year follow-up results for 104 total hip replacements with the Zweymüller Alloclassic stem and a threaded cup in 94 patients. The present study is a clinical and radiographic outcome update after a minimum follow-up of 25 years. Four patients (4 hips) were lost and 46 patients (50 hips) died, leaving 44 patients (50 hips) available for follow-up. Since our previous report, 7 cups and 2 stems were revised. At 20 years, the probability of survival of any component was 84.1% (95% confidence interval [CI], 73.91% to 94.29%) and the cumulative probability of not having stem loosening was 95.9% (95% CI, 95.51% to 96.29%). We observed proximal femoral osteolysis in 15 hips (30%), cortical hypertrophy in 21 hips (42%), and proximal femoral osteopenia in 30 hips (60%). The Zweymüller Alloclassic stem continues to provide excellent results after extended follow-up. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Asunto(s)
Artroplastia de Reemplazo de Cadera/instrumentación , Prótesis de Cadera , Anciano , Artroplastia de Reemplazo de Cadera/métodos , Femenino , Estudios de Seguimiento , Humanos , Estimación de Kaplan-Meier , Masculino , Persona de Mediana Edad , Evaluación de Resultado en la Atención de Salud , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/epidemiología , Falla de Prótesis , Reoperación/estadística & datos numéricos , Estudios Retrospectivos
9.
J Arthroplasty ; 31(2): 484-90, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26489381

RESUMEN

BACKGROUND: Factors related to the patient, implant, and surgery have been associated to the rate of dislocation for total hip arthroplasty (THA). We ask if the position of the cup and the reconstruction of the abductor mechanism actually lower the THA dislocation rate. METHODS: We evaluated 1318 patients (1414 hips) undergoing cementless THA between 1992 and 2012. All THAs had a 28- or a 32-mm femoral head size. Hip reconstruction was radiologically assessed evaluating cup position and the hip rotation center according to Ranawat. The reconstruction of the abductor mechanism was measured using 2 variables: the lever arm distance and the height of the greater trochanter. RESULTS: There were 38 dislocations (2.7%). After controlling the relevant confounding variables, such as demographic and implant data, multivariate regression analysis showed that the most important factors associated with dislocation were a greater distance to the anatomic hip rotation center and hips outside 2 safe windows for cup position (acetabular inclination and version angles) and abductor mechanism (lever arm distance and height of the greater trochanter). CONCLUSION: A proper reconstruction of the hip is essential to decrease the risk of dislocation after primary THA. The weakness of the abductor muscles of the hip may be one of the most important causes for dislocation.


Asunto(s)
Artroplastia de Reemplazo de Cadera/efectos adversos , Luxación de la Cadera/etiología , Articulación de la Cadera/cirugía , Prótesis de Cadera/efectos adversos , Acetábulo/cirugía , Adulto , Anciano , Artroplastia de Reemplazo de Cadera/estadística & datos numéricos , Fenómenos Biomecánicos , Femenino , Fémur/cirugía , Cabeza Femoral/cirugía , Luxación de la Cadera/epidemiología , Articulación de la Cadera/fisiología , Humanos , Luxaciones Articulares , Masculino , Persona de Mediana Edad , Músculo Esquelético/fisiología , Estudios Prospectivos , Rotación , España/epidemiología , Resultado del Tratamiento
10.
Clin Orthop Relat Res ; 473(12): 3882-91, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26245166

RESUMEN

BACKGROUND: Most acetabular revisions are managed with cementless hemispherical or elliptical metal implants relying on bone ingrowth. Nonetheless, loss of acetabular bone stock and inability to achieve secure component fixation represent challenges in the setting of revision total hip arthroplasty. Impaction bone grafting (IBG) using allograft represents one option for treatment of this problem. However, cup migration and bone graft resorption are limitations when IBG is used for large segmental defects, and the precise role of IBG as well as the use of mesh (and the kinds of defects for which mesh does not work well) in this setting remains unknown. QUESTIONS/PURPOSES: We therefore evaluated patients undergoing acetabular revision surgery using IBG and a cemented cup in large bone defects to determine (1) the frequency with which the hip center could be restored in hips with Paprosky 3A and 3B defects and in hips with or without the use of metallic mesh during surgery; (2) survivorship of IBG acetabular-revision reconstructions in patients with severe Paprosky 3A and 3B defects; and (3) risk factors for failure of the reconstruction, including the use of mesh and defect severity (3A versus 3B). METHODS: Between 1997 and 2009, we performed 226 acetabular revisions using IBG. During that time, indications for using IBG in this setting included Paprosky 3A and 3B defects without pelvic discontinuity. Of these, 204 (90.2%) were available for followup at a minimum of 5 years (mean, 10 years; range, 5-17 years). There were 100 hips with an intraoperative bone defect of Paprosky 3A and 104 with a 3B. Medial or rim acetabular uncontained defects were treated with medial and/or lateral metallic mesh in 142 hips. We determined the postoperative radiological cup position and acetabular reconstruction of the hip center according to Ranawat in both groups. We assessed the appearance of cup loosening and the possible risk factors with regression analysis. RESULTS: Mean postoperative acetabular abduction angle and vertical, horizontal, and hip rotation center distances improved (p < 0.001 in all parameters). Nine hips showed radiological loosening in the group with bone defect 3A and 16 in Group 3B. The survival rate for loosening at 15 years was 83% (95% confidence interval [CI], 71%-95%) for Group 3A and 73% (95% CI, 60%-84%) for Group 3B (p = 0.04). The survivorship for loosening when using mesh or not at 15 years was: no mesh 89% (95% CI, 74%-99%), medial mesh 85% (95% CI, 72%-97%), lateral mesh 80% (95% CI, 67%-91%), and medial and lateral meshes 54% (95% CI, 31%-76%) (p = 0.008). After controlling the most relevant confounding variables we found that the most important factor associated with loosening was lateral mesh use (p = 0.008; hazard ratio, 2.942; 95% CI, 1.328-6.516). CONCLUSIONS: IBG provides an improvement in reconstruction of the hip rotation center in acetabular revision surgery. Although results are good for contained or medial large defects, hips with a rim or lateral segmental defect may need other options for reconstruction of these challenging surgeries. LEVEL OF EVIDENCE: Level III, therapeutic study.


Asunto(s)
Acetábulo/cirugía , Artroplastia de Reemplazo de Cadera/efectos adversos , Trasplante Óseo/instrumentación , Articulación de la Cadera/cirugía , Complicaciones Posoperatorias/cirugía , Mallas Quirúrgicas , Acetábulo/diagnóstico por imagen , Acetábulo/fisiopatología , Adulto , Anciano , Anciano de 80 o más Años , Aloinjertos , Artroplastia de Reemplazo de Cadera/instrumentación , Trasplante Óseo/efectos adversos , Femenino , Articulación de la Cadera/diagnóstico por imagen , Articulación de la Cadera/fisiopatología , Prótesis de Cadera , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/fisiopatología , Radiografía , Índice de Severidad de la Enfermedad , Factores de Tiempo , Resultado del Tratamiento
11.
J Arthroplasty ; 29(11): 2078-83, 2014 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-25129452

RESUMEN

Precise indications for THA remain unclear and regional differences might exist in selecting patients for surgery. In this study we investigate radiological OA grade and self-reported quality of life in 909 patients undergoing THA in 16 centers across US and Europe. Patients in US were younger and had higher BMI. More patients with mild Tönnis OA grade underwent surgery in the US compared to Europe. Patients in the US had significantly higher pain VAS and significantly lower SF-36 Physical, while having significantly higher EQ-VAS scores preoperatively. Patient demographics and disease severity according to radiological OA grade and self-reported survey scores vary between the United States and Europe. This knowledge can be used in the interpretation of US and European based studies on outcome following THA.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Osteoartritis de la Cadera/diagnóstico por imagen , Osteoartritis de la Cadera/cirugía , Anciano , Europa (Continente) , Femenino , Encuestas de Atención de la Salud , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida , Radiografía , Resultado del Tratamiento , Estados Unidos
12.
Hip Int ; 24 Suppl 10: S33-6, 2014 Oct 02.
Artículo en Inglés | MEDLINE | ID: mdl-24970036

RESUMEN

Cup revision can be a highly complex operation depending on the bone defect. In acetabular defects of less than 30% (Paprosky types 1 and 2), porous hemispherical cementless cups fixed with screws give good results. Modern trabecular metal designs improve these good results. Morsellised allografts are useful for filling cavitary defects. In acetabular defects greater than 30% (Paprosky types 3A and 3B), impacted morsellised allografts with a cemented cup technique produce good results. Difficult cases with pelvic discontinuity require reconstruction of the acetabulum with acetabular plates or large cup-cages to solve these difficult problems.


Asunto(s)
Acetábulo/patología , Acetábulo/cirugía , Artroplastia de Reemplazo de Cadera/efectos adversos , Trasplante Óseo/métodos , Acetábulo/diagnóstico por imagen , Anciano , Aloinjertos , Artroplastia de Reemplazo de Cadera/métodos , Cementos para Huesos , Femenino , Estudios de Seguimiento , Articulación de la Cadera/diagnóstico por imagen , Articulación de la Cadera/cirugía , Prótesis de Cadera , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Falla de Prótesis , Radiografía , Reoperación/métodos , Medición de Riesgo , Resultado del Tratamiento
13.
Clin Orthop Relat Res ; 471(12): 3912-21, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23430720

RESUMEN

BACKGROUND: Healing and functional recovery have been reported using an extensively porous-coated stem in Vancouver B2 and B3 periprosthetic fractures; however, loss of cortical bone has been observed when using these stems in revision surgery for aseptic loosening. However, it is unclear whether this bone loss influences subsequent loosening. QUESTION/PURPOSES: We analyze the healing fracture rate and whether the radiographic changes observed around and extensively porous-coated stem used for periprosthetic fractures affect function or loosening. METHODS: We retrospectively reviewed 35 patients with periprosthetic fractures (20 Vancouver B2 and 15 Vancouver B3). Patients' mean age at surgery was 80 years (range, 51-86 years). No cortical struts were used in this series. We evaluated radiographs for signs of loosening or subsidence. The cortical index and the femoral cortical width were measured at different levels on the immediate pre- and postoperative radiographs and at different periods of followup. The minimum followup was 3 years (mean, 8.3 years; range, 3-17 years). RESULTS: All fractures had healed, and all stems were clinically and radiographically stable at the end of followup. Nineteen hips showed nonprogressive radiographic subsidence during the first 3 postoperative months without clinical consequences. The cortical index and the lateral and medial cortical thickness increased over time. Increase of femoral cortex thicknesses was greater in cases with moderate preoperative osteoporosis and in cases with stems less than 16 mm in thickness. CONCLUSIONS: Our data suggest an extensively porous-coated stem for Vancouver B2 and B3 periprosthetic fractures leads to a high rate of union and stable fixation. Cortical index and lateral cortex thickness increased in these patients with periprosthetic fractures. Patients with moderate osteoporosis and those using thin stems showed a major increase in femoral cortex thickness over time.


Asunto(s)
Fracturas del Fémur/cirugía , Curación de Fractura , Fracturas Periprotésicas/cirugía , Recuperación de la Función , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Cadera , Femenino , Fracturas del Fémur/diagnóstico por imagen , Prótesis de Cadera , Humanos , Masculino , Persona de Mediana Edad , Fracturas Periprotésicas/diagnóstico por imagen , Radiografía , Estudios Retrospectivos , Resultado del Tratamiento
15.
Clin Orthop Relat Res ; 470(11): 3014-23, 2012 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-22576930

RESUMEN

BACKGROUND: Uncemented press-fit cups provide bone fixation in primary THA, but the use of screws is sometimes necessary to achieve primary stability of the socket. However, it is unclear whether and when screws should be used. QUESTION/PURPOSES: We analyzed the factors related to screw use with a press-fit uncemented cup and assessed whether screw use is associated with the same rates of loosening and revision as a press-fit technique. METHODS: We retrospectively reviewed 248 patients who underwent THA using the same prosthetic design. Eighty-eight hips had screws to achieve primary cup fixation (Group 1), and 189 did not (Group 2). Mean age was 50 years (range, 14-73 years). We analyzed factors related to the patient, acetabular type, and reconstruction of the rotation center of the hip. Minimum followup was 5 years (mean, 8.9 years; range, 5-12 years). RESULTS: We found higher screw use in women, patients with less physical activity, Acetabular Types A or C, and a distance from the center of the prosthetic femoral head to the normal center of rotation of more than 3 mm. There were four revisions in Group 1 and five in Group 2. Eight hips had radiographic loosening in Group 1 and nine in Group 2. Cups with a postoperative abduction angle of more than 50° had a higher risk for loosening. CONCLUSIONS: Press fit was achieved less frequently in women and patients with Acetabular Types A or C and less physical activity; a closer distance to the normal center of rotation decreased screw use. Screw use to augment fixation achieved survival similar to that of a press-fit cup. LEVEL OF EVIDENCE: Level II, prognostic study. See Instructions for Authors for a complete description of levels of evidence.


Asunto(s)
Acetábulo/diagnóstico por imagen , Artroplastia de Reemplazo de Cadera/métodos , Articulación de la Cadera/cirugía , Prótesis de Cadera , Adolescente , Adulto , Anciano , Materiales Biocompatibles , Cementos para Huesos , Tornillos Óseos , Durapatita , Femenino , Articulación de la Cadera/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Falla de Prótesis , Radiografía , Estudios Retrospectivos , Factores Sexuales , Adulto Joven
16.
Acta Biomater ; 8(3): 1146-55, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22198139

RESUMEN

Wear particle-mediated osteolysis is one of the major problems affecting long-term survival of orthopaedic prostheses, frequently progressing to failure of fixation and revision surgery. Upon challenging with wear particles, macrophages and various other types of cells release soluble factors that stimulate the resorptive activity of osteoclasts and impair the function and activity of osteoblasts. Extracellular Hsp72 has been reported to activate macrophages and up-regulate pro-inflammatory cytokine production, although its role in osteolysis has not been established yet. The purpose of our study was to evaluate the involvement of this protein in the inflammatory response to wear particles that leads to periprosthetic osteolysis. To this end, we used interfacial tissues and blood samples from patients undergoing revision surgery due to aseptic loosening of cementless acetabular cups. Confocal microscopy indicated that Hsp72 co-localises with CD14(+) cells of interfacial tissues. Levels of Hsp72 in the culture media from periprosthetic membranes cultured ex vivo decreased along culture time and Hsp72 levels in sera from patients were lower and under the assay detection limit compared with those from age-matched control subjects. This suggests that interfacial tissues are not actively producing the protein but likely recruit it from peripheral circulation. Incubation of human macrophages with titanium (Ti) particles decreased the release of Hsp72 into culture media. Treatment with recombinant human Hsp72 enhanced considerably IL-6 levels in culture media which were not modified after macrophage co-stimulation with Ti particles, while pre-incubation with Hsp72 increased the Ti particle-induced TNF-α and IL-1ß production. Altogether, these data indicate that extracellular Hsp72 amplifies the inflammatory response to wear debris by interacting with resident macrophages in periprosthetic tissues.


Asunto(s)
Proteínas del Choque Térmico HSP72/sangre , Prótesis de Cadera/efectos adversos , Activación de Macrófagos , Osteoclastos/metabolismo , Osteólisis/sangre , Falla de Prótesis/efectos adversos , Titanio/efectos adversos , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Cadera , Células Cultivadas , Femenino , Humanos , Inflamación/sangre , Inflamación/etiología , Inflamación/patología , Interleucina-1beta/sangre , Masculino , Persona de Mediana Edad , Osteoclastos/patología , Osteólisis/etiología , Osteólisis/patología , Factor de Necrosis Tumoral alfa/sangre
17.
Clin Orthop Relat Res ; 470(5): 1421-30, 2012 May.
Artículo en Inglés | MEDLINE | ID: mdl-21879408

RESUMEN

BACKGROUND: THA is a concern in juvenile idiopathic arthritis (JIA) owing to patients' youth, poor bone stock, and small physical size. QUESTIONS/PURPOSES: We asked whether (1) uncemented alumina-on-alumina THAs have good clinical and radiographic results at midterm followup in young patients with inflammatory arthritis and end-stage hip disease secondary to JIA, and (2) the anatomic center of rotation of the hip could be reconstructed in patients with acetabular protrusion. We also assessed the rate of surgical complications. PATIENTS AND METHODS: We retrospectively reviewed 31 alumina-on-alumina THAs in 21 patients with a mean age of 30.9 years (range, 14-48 years). Minimum followup until the time of revision of any component or the latest evaluation was 16 months. For nonrevised cases, the minimum followup was 60 months (range, 60-108 months). Acetabular protrusion was mild in 17 hips (Group 1) and moderate-severe in 14 (Group 2). Bone autograft was used to reconstruct the acetabulum in Group 2. Acetabular reconstruction was evaluated according to Ranawat et al. RESULTS: One cup was revised owing to aseptic loosening at 16 months; the remaining hips showed good clinical and radiographic results. The mean postoperative horizontal distance and the distance between the center of the head of the prosthesis and the true center of the femoral head improved in Group 2. There were no complications related to alumina. CONCLUSIONS: Although THA is a technically demanding procedure in patients with JIA, uncemented alumina-on-alumina THA provides pain relief and improves quality of life. In patients with acetabular protrusion, bone grafts enable anatomic cup positioning. Continued followup will be required to determine whether the alumina-on-alumina bearings in patients with JIA result in less osteolysis and loosening. LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.


Asunto(s)
Óxido de Aluminio , Artritis Juvenil/cirugía , Artroplastia de Reemplazo de Cadera/rehabilitación , Prótesis de Cadera , Osteoartritis de la Cadera/cirugía , Falla de Prótesis , Acetábulo/patología , Acetábulo/cirugía , Adolescente , Adulto , Artritis Juvenil/complicaciones , Artroplastia de Reemplazo de Cadera/efectos adversos , Trasplante Óseo , Cementación , Femenino , Luxación de la Cadera/etiología , Luxación de la Cadera/cirugía , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Cadera/etiología , Complicaciones Posoperatorias , Diseño de Prótesis , Reoperación , Estudios Retrospectivos , Adulto Joven
18.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 46(4): 193-199, jul.-ago. 2011.
Artículo en Español | IBECS | ID: ibc-89867

RESUMEN

Objetivos. Estudiar los efectos del tratamiento de los pacientes con fractura de cadera en una unidad ortogeriátrica conjunta entre los servicios de traumatología y geriatría comparados con el tratamiento hospitalario habitual y analizar las diferencias de costes entre ambos sistemas de asistencia. Material y métodos. Estudio prospectivo cuasi-experimental de intervención, aleatorizado, en 506 pacientes ingresados en un hospital terciario con el diagnóstico de fractura de cadera osteoporótica. El sistema habitual de tratamiento fue el ingreso a cargo de traumatología con interconsulta a geriatría (tipo IC) y el sistema a estudio consistió en el ingreso en una unidad ortogeriátrica (UOG) para el tratamiento conjunto integrado entre los especialistas en traumatología y geriatría. Éste incluyó la designación de un interlocutor único por cada servicio, seguimiento por la enfermera de ortogeriatría, valoración geriátrica precoz, atención clínica diaria coordinada, pase de visita conjunto semanal y planificación coordinada de la programación quirúrgica, del inicio de la deambulación y del destino y momento del alta. Resultados. Se incluyó a 255 pacientes consecutivos ingresados en la UOG y 251 tratados simultáneamente mediante IC. No existieron diferencias, salvo por una edad ligeramente inferior en el grupo de UOG, en las características previas ni en la tasa de intervención quirúrgica de ambos grupos. En los pacientes de la UOG fue más frecuente recibir rehabilitación en la fase aguda, ser capaz de caminar al alta y ser derivado a unidades de recuperación funcional (todas con p<0,05). Los pacientes ingresados en la UOG recibieron una valoración geriátrica más precoz y fueron intervenidos antes que los tratados mediante IC (p<0,01). La estancia en la planta de agudos fue un 34% menor en los pacientes de la UOG (media 12,48±5 frente a 18,9±8,6 días; p<0,001) (mediana de 12 [9-14] días frente a 17 [13-23]; p<0,001). La estancia hospitalaria total, incluida la estancia en las unidades de recuperación funcional, fue un 11% menor en los pacientes de la UOG (media 21,16±14,7 frente a 23,9±13,8 días; p<0,001) (mediana 14 [10-31] frente a 20 [14-30] días; p<0,001). La UOG obtuvo un ahorro de costes por paciente de entre 1.207 € y 1.633 € mediante el modelo de coste por proceso y de 3.741 € mediante el modelo de costes por estancias. Conclusiones. La UOG es un nivel asistencial que aporta mejoras en la evolución funcional de los pacientes y una reducción total de estancias hospitalarias. En base a ello reduce los costes de asistencia. Estos resultados hacen recomendable este sistema de atención a los pacientes con fractura de cadera en fase aguda(AU)


Objective. To study the effects of the management of hip fracture patients in an acute orthogeriatric unit shared between the departments of Orthopedic Surgery and Geriatrics compared with the usual hospital care, and to analyse financial differences in both systems of care. Method. Prospective quasy-experimental randomized intervention study in 506 patients admited to a terciary hospital with an osteoporotic hip fracture. The usual model of care was the admission to the orthopedic ward with a request to Geriatrics (RC) and the study model consisted of the admission to an orthogeriatric unit (OGU) for the shared co-management between orthopaedic surgeons and geriatricians. This model included the appointment of one spokesperson from each department, the specialist geriatric nurse management, early geriatric assessment, shared daily clinical care, weekly joint ward round and coordinated planning of the surgery schedule, the start of the ambulation and the time and setting of patient discharge. Results. Two hundred fifty five consecutive patients admitted to the OGU and 251 patients managed simultaneusly by the RC model were included. Except for a mean age slightly lower in the OGU group, there were no differences neither in the baseline patients characteristics nor in the surgical rates between the two groups. Among the OGU patients group it was more frequent to receive rehabilitation in the acute setting, to be able to walk at discharge and to be referred to a geriatric rehabilitation unit (all with P<.05). The OGU patients received geriatric assessment and were operated on earlier than the RC patients (P<.001). The length of stay in the acute ward was 34% shorter in the OGU patients (mean 12.48±5 vs 18.9±8.6 days, P<.001) (median 12 [9-14] vs 17 [13-23] days, P<.001). The whole hospital length of stay, including the days spent in the geriatric rehabilitation units, was 11% shorter in the OGU patients (mean 21.16 ±14.7 vs 23.9 ±13.8 days, P<0.05) (median 14 [10-31] vs 20 [14-30] days, P<.001). The OGU saved 1,207 € to 1,633 € per patient when estimated by the costs for process model, and 3,741 € when estimated by the costs for stay model. Conclusions. The OGU is a hospital setting that provides an improvement in the patients functional outcome and a reduction in the hospital length of stay. Therefore it saves health care resources. These findings show the OGU as an advisable setting for the acute care of hip fracture patients(AU)


Asunto(s)
Humanos , Masculino , Femenino , Anciano , Anciano de 80 o más Años , Enfermedad Aguda/economía , Fracturas de Cadera/epidemiología , Prótesis de Cadera/economía , Costos y Análisis de Costo/métodos , Costos y Análisis de Costo/estadística & datos numéricos , /economía , Costos y Análisis de Costo/economía , Costos y Análisis de Costo/tendencias , Estudios Prospectivos , Análisis de Datos/métodos , Análisis de Datos/estadística & datos numéricos
19.
Rev Esp Geriatr Gerontol ; 46(4): 193-9, 2011.
Artículo en Español | MEDLINE | ID: mdl-21507529

RESUMEN

OBJECTIVE: To study the effects of the management of hip fracture patients in an acute orthogeriatric unit shared between the departments of Orthopedic Surgery and Geriatrics compared with the usual hospital care, and to analyse financial differences in both systems of care. METHOD: Prospective quasy-experimental randomized intervention study in 506 patients admitted to a terciary hospital with an osteoporotic hip fracture. The usual model of care was the admission to the orthopedic ward with a request to Geriatrics (RC) and the study model consisted of the admission to an orthogeriatric unit (OGU) for the shared co-management between orthopaedic surgeons and geriatricians. This model included the appointment of one spokesperson from each department, the specialist geriatric nurse management, early geriatric assessment, shared daily clinical care, weekly joint ward round and coordinated planning of the surgery schedule, the start of the ambulation and the time and setting of patient discharge. RESULTS: Two hundred fifty five consecutive patients admitted to the OGU and 251 patients managed simultaneously by the RC model were included. Except for a mean age slightly lower in the OGU group, there were no differences neither in the baseline patients characteristics nor in the surgical rates between the two groups. Among the OGU patients group it was more frequent to receive rehabilitation in the acute setting, to be able to walk at discharge and to be referred to a geriatric rehabilitation unit (all with P < .05). The OGU patients received geriatric assessment and were operated on earlier than the RC patients (P < .001). The length of stay in the acute ward was 34% shorter in the OGU patients (mean 12.48 ± 5 vs 18.9 ± 8.6 days, P < .001) (median 12 [9-14] vs 17 [13-23] days, P < .001). The whole hospital length of stay, including the days spent in the geriatric rehabilitation units, was 11% shorter in the OGU patients (mean 21.16 ± 14.7 vs 23.9 ± 13.8 days, P < 0.05) (median 14 [10-31] vs 20 [14-30] days, P < .001). The OGU saved 1,207 € to 1,633 € per patient when estimated by the costs for process model, and 3,741 € when estimated by the costs for stay model. CONCLUSIONS: The OGU is a hospital setting that provides an improvement in the patients functional outcome and a reduction in the hospital length of stay. Therefore it saves health care resources. These findings show the OGU as an advisable setting for the acute care of hip fracture patients.


Asunto(s)
Fracturas de Cadera/economía , Fracturas de Cadera/cirugía , Grupo de Atención al Paciente , Anciano de 80 o más Años , Costos y Análisis de Costo , Femenino , Geriatría , Unidades Hospitalarias , Humanos , Masculino , Ortopedia , Estudios Prospectivos
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA