RESUMEN
INTRODUCTION: The indication and extent of axillary lymph node dissection in breast cancer remains open to controversy. MATERIALS AND METHOD: In this context, a 20-year survival study has been made of 1600 breast cancer patients subjected during surgical treatment to systematic dissection of the acromiothoracic vascular pedicle together with the accompanying lymph nodes (Rotter and Grossman interpectoral lymph node groups). An anatomical study of these nodes was also conducted in 100 necropsies, with the evaluation of 200 acromiothoracic vascular pedicles. RESULTS: The interpectoral lymph nodes were anatomically present in 42% of the necropsies and in 35.1% of the patients subjected to surgery. The prognosis was much worse in cases of neoplastic infiltration of the interpectoral lymph nodes (Kaplan-Meier survival study), regardless of the influence of other prognostic factors. CONCLUSIONS: In view of the results obtained, the designation of grade N3 of the TNM classification is proposed for malignancies with positive interpectoral lymph node infiltration.
Asunto(s)
Neoplasias de la Mama/mortalidad , Metástasis Linfática , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Autopsia/métodos , Beclometasona , Neoplasias de la Mama/patología , Neoplasias de la Mama/cirugía , Niño , Preescolar , Disección/métodos , Femenino , Variación Genética , Humanos , Lactante , Tablas de Vida , Escisión del Ganglio Linfático , Ganglios Linfáticos/anatomía & histología , Persona de Mediana Edad , Estadificación de Neoplasias , Especificidad de Órganos , Pronóstico , Estudios Retrospectivos , Análisis de Supervivencia , Tórax/anatomía & histologíaRESUMEN
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Introduction. The indication and extent of axillarylymph node dissection in breast cancer remainsopen to controversy.Materials and method. In this context, a 20-yearsurvival study has been made of 1600 breast cancerpatients subjected during surgical treatment to systematicdissection of the acromiothoracic vascularpedicle together with the accompanying lymphnodes (Rotter and Grossman interpectoral lymphnode groups). An anatomical study of these nodeswas also conducted in 100 necropsies, with the evaluationof 200 acromiothoracic vascular pedicles.Results. The interpectoral lymph nodes were anatomicallypresent in 42% of the necropsies and in35.1% of the patients subjected to surgery. The prognosiswas much worse in cases of neoplastic infiltrationof the interpectoral lymph nodes (Kaplan-Meier survival study), regardless of the influence ofother prognostic factors.Conclusions. In view of the results obtained, thedesignation of grade N3 of the TNM classification isproposed for malignancies with positive interpectorallymph node infiltration