RESUMEN
OBJECTIVE: Analyze the safety and efficacy of the outpatient treatment of uncomplicated acute diverticulitis and a costs analysis. METHOD: We conducted a prospective, non-randomized study between June 2014 and June 2017. We included all patients diagnosed of uncomplicated acute diverticulitis based on clinical and abdominal computed tomography scan in the Emergency Department of the University Hospital San Juan de Alicante (Spain). Outpatient treatment consisted of oral antibiotics for 7 days (amoxicillin-clavulanate or ciprofloxacin and metronidazole in patients with betalactamic allergy), liquid diet for 72 h and analgesics. Costs were evaluated according to the Law of Rates of Valencian Community. RESULTS: Ninety patients were included, 49 females and 41 males with a median age of 56 years. Success rate was 95.5% (n = 86) requiring hospital admission 4 patients (4.5%). Antibiotic treatment was amoxicillin-clavulanate in 82 patients (91.1%) and ciprofloxacin and metronidazole in 8 (8.9%). Cost savings per patient was approximately 1985 comparing with hypothetically all inpatient treatment. CONCLUSIONS: Outpatient treatment of uncomplicated acute diverticulitis can be performed successfully in most patients allowing an important cost savings.
OBJETIVO: Evaluar la seguridad y la eficacia del tratamiento con antibiótico oral para la diverticulitis aguda no complicada, y realizar un análisis de costos. MÉTODO: Estudio prospectivo, no aleatorizado, entre junio de 2014 y junio de 2017. Se incluyeron todos los pacientes diagnosticados de diverticulitis aguda no complicada según la clínica y la tomografía abdominal en el servicio de urgencias del Hospital Universitario San Juan de Alicante (España). El tratamiento ambulatorio consistió en antibiótico oral durante 7 días (amoxicilina-ácido clavulánico o ciprofloxacino y metronidazol en alérgicos a los betalactámicos), dieta líquida durante 72 horas y analgésicos. Los costos fueron evaluados según la Ley de Tasas de la Comunidad Valenciana. RESULTADOS: Se incluyeron 90 pacientes, 49 mujeres y 41 hombres, con una mediana de edad de 56 años. La tasa de éxito fue del 95.5% (n = 86), necesitando ingreso hospitalario cuatro pacientes (4.5%). El tratamiento antibiótico empleado fue amoxicilina-ácido clavulánico en 82 pacientes (91.1%) y ciprofloxacino con metronidazol en ocho pacientes (8.9%). El ahorro por paciente fue de 1985 euros en comparación con el hipotético ingreso de todos los pacientes. CONCLUSIONES: El tratamiento ambulatorio de la diverticulitis aguda no complicada se completó con éxito en la mayoría de los pacientes, permitiendo una importante reducción del gasto.
Asunto(s)
Atención Ambulatoria , Diverticulitis/terapia , Enfermedad Aguda , Adulto , Anciano , Diverticulitis/tratamiento farmacológico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Resultado del TratamientoRESUMEN
BACKGROUND: Pylephlebitis or septic thrombophlebitis of the portal venous system is a rare but serious complication of intra-abdominal infections which drain into the portal venous system. Its diagnosis is based on clinical suspicion and imaging tests, mainly a computed tomography scan, given the lack of specificity of the signs and symptoms. Spread of septic emboli is the major cause of morbidity and mortality. The aim of the study was to analyse patients diagnosed in our hospital. MATERIAL AND METHODS: Retrospective descriptive study of patients diagnosed with pylephlebitis in our hospital. CLINICAL CASES: Four patients were included, 3 men and one woman. In 3 cases it was acute cholecystitis that led to the diagnosis of pylephlebitis at the same time as the intra-abdominal infection. Emergency surgery was performed in one case, whilst the other 2 were treated conservatively. Blood cultures were performed in all cases, and empirical antibiotic treatment was used. In the only case of acute appendicitis, diagnosis of pylephlebitis was achieved during the study of postoperative fever, with empirical antibiotic treatment also being started. The haematologist was requested to start the required anticoagulation therapy in all cases. CONCLUSIONS: Pylephlebitis is a rare complication of intra-abdominal infections that may make lead to a worse outcome. A high level of suspicion is required as well as imaging tests to make an early diagnosis and appropriate treatment.
Asunto(s)
Apendicitis/complicaciones , Infecciones por Bacteroides/complicaciones , Colecistitis/complicaciones , Embolia/etiología , Infecciones por Bacterias Grampositivas/complicaciones , Infecciones por Klebsiella/complicaciones , Vena Porta , Tromboflebitis/etiología , Adulto , Anciano , Anciano de 80 o más Años , Antibacterianos/uso terapéutico , Anticoagulantes/uso terapéutico , Apendicectomía , Bacteriemia/etiología , Infecciones por Bacteroides/tratamiento farmacológico , Infecciones por Bacteroides/cirugía , Colecistectomía , Colecistitis/cirugía , Coinfección , Terapia Combinada , Urgencias Médicas , Enterococcus faecium/aislamiento & purificación , Femenino , Infecciones por Bacterias Grampositivas/tratamiento farmacológico , Infecciones por Bacterias Grampositivas/cirugía , Humanos , Infecciones por Klebsiella/tratamiento farmacológico , Infecciones por Klebsiella/cirugía , Klebsiella oxytoca/aislamiento & purificación , Klebsiella pneumoniae/aislamiento & purificación , Hígado/irrigación sanguínea , Hígado/patología , Masculino , Persona de Mediana Edad , Vena Porta/diagnóstico por imagen , Vena Porta/microbiología , Estudios Retrospectivos , Tromboflebitis/diagnóstico por imagen , Tromboflebitis/tratamiento farmacológico , Tromboflebitis/microbiología , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND: Epiploic appendagitis is an atypical cause of abdominal pain whose knowledge could avoid diagnostic or treatment errors. Diagnosis has been performed with abdominal ultrasound or tomography with the only treatment being nonsteroidal anti-inflammatory drugs. OBJECTIVE: To analyze patients diagnosed in our hospital. METHODS: We performed a 4-year retrospective and descriptive study (March 2009-March 2013) of patients diagnosed with epiploic appendagitis in our hospital. RESULTS: Seventeen patients were included, 14 females and three males with a median age of 57 years. Symptom delay was 72 h. Abdominal pains were located in the left lower quadrant in 64.7% and right lower quadrant in 35.3% of patients. Blood test demonstrated leukocytes 6,300 (5,000-9,500), neutrophils 61.6% (57-65.8), and C reactive protein 1.5 (0.85-2.92). Diagnosis was confirmed with abdominal ultrasound or tomography in 88.2% and intraoperatively in 11.8%. CONCLUSIONS: Epiploic appendagitis was more frequent in women. Abdominal pain was located in the lower quadrant, more predominant in left than right. Blood tests were normal except for increased levels of C-reactive protein. Diagnosis was made mostly preoperatively due to imaging tests, avoiding unnecessary surgical intervention.
ANTECEDENTES: la apendagitis epiploica es una causa poco frecuente de dolor abdominal cuyo conocimiento podría evitar errores diagnósticos y terapéuticos. El diagnóstico suele establecerse mediante ecografía o tomografía abdominal; el tratamiento es sintomático, con antiinflamatorios. OBJETIVO: analizar los casos diagnosticados en nuestro centro. MATERIAL Y MÉTODOS: estudio retrospectivo y descriptivo de pacientes con diagnóstico de apendagitis epiploica durante 4 años (marzo 2009 a marzo 2013). RESULTADOS: se incluyeron 17 pacientes, 14 mujeres y 3 hombres, con una mediana de edad de 57 años. El periodo de latencia de los síntomas fue 72 horas. En 64.7% de los pacientes el dolor abdominal se localizó en el cuadrante inferior izquierdo y en 35.3% en el derecho. Laboratorio: leucocitos 6,300 (5,000-9,500), neutrófilos 61.6% (57- 65.8), proteína C reactiva 1.5 (0.85-2.92). El diagnóstico se confirmó mediante ecografía o tomografía abdominal en 88.2%, e intraoperatorio en 11.8%. CONCLUSIONES: la apendagitis epiploica fue más frecuente en mujeres. La clínica fue dolor abdominal en los cuadrantes inferiores, más frecuente en el lado izquierdo, con RESULTADOS de laboratorio normales, excepto la elevación de la proteína C reactiva. En la mayoría de los casos el diagnóstico se estableció preoperatoriomente, gracias al uso de pruebas radiológicas que evitó las intervenciones quirúrgicas innecesarias.
Asunto(s)
Dolor Abdominal/etiología , Colon/patología , Enfermedades del Colon/diagnóstico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Apendicitis/diagnóstico , Proteína C-Reactiva/análisis , Niño , Colon/diagnóstico por imagen , Colon/cirugía , Enfermedades del Colon/sangre , Enfermedades del Colon/complicaciones , Enfermedades del Colon/diagnóstico por imagen , Diagnóstico Diferencial , Femenino , Humanos , Infarto/diagnóstico , Masculino , Persona de Mediana Edad , Epiplón/irrigación sanguínea , Paniculitis Peritoneal/diagnóstico , Estudios Retrospectivos , España/epidemiología , Tomografía Computarizada por Rayos X , Ultrasonografía , Adulto JovenRESUMEN
BACKGROUND: Appendiceal diverticulitis (AD) is a rare cause of acute appendicitis (AA) which is most frequently diagnosed after appendectomy in pathological study. OBJECTIVE: To compare AA versus AD. METHODS: Retrospective analytic study in avperiod of 51 months fom January 2009 to March 2013 in the Hospital Universitario San Juan de Alicante (Spain), including patients with clinical or radiological suspicious of acute appendicitis which was confirmed intraoperatively and with the pathological study. RESULTS: We included 449 patients, 442 typical AA (98.5%) and 7AD (1.5%). DA was more frequent in women (57%) with a median age of 44 years old (range 37 to 57 years old), whereas AA was more frequent in men (61%) with a median age of 28 years old (range 15 to 46 years old). Leukocyte count, neutrophils and C-reactive protein were respectively 13,300 per mm3 (range 10,700 to 15,700 per mm3), 87.1% (range 84.6 to 89.6%) and 1.82 mg/dL (range 0.59 to 5.31 mg/dL) in AD versus 14,700 per mm3 (range 12,300 to 17,600 per mm), 81.6% (range 75.1 to 86.4%) and 2.71 mg/dL (range 0.67 to 75 mg/dL) in AA. Alvarado score and appendicitis diagnostic score were respectively 7 (range 6 to 8) and 6 (range 5 to 7) in AD and 7 (range 5 to 7) and 6 (range 5 to 6) in AA. An appendiceal perforation was seen in 3 AD (43%) and 80 AA (18%). CONCLUSION: AD appeared in older patients with a clinical and blood test profile similar to AA but with a higher perforation rate.
Asunto(s)
Apendicitis/diagnóstico , Diverticulitis/diagnóstico , Enfermedad Aguda , Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto JovenRESUMEN
BACKGROUND: Appendiceal diverticulitis (AD) is a rare cause of acute appendicitis (AA) which is most frequently diagnosed after appendectomy in pathological study. OBJECTIVE: To compare AA versus AD. METHODS: Retrospective analytic study in avperiod of 51 months fom January 2009 to March 2013 in the Hospital Universitario San Juan de Alicante (Spain), including patients with clinical or radiological suspicious of acute appendicitis which was confirmed intraoperatively and with the pathological study. RESULTS: We included 449 patients, 442 typical AA (98.5
) and 7AD (1.5
). DA was more frequent in women (57
) with a median age of 44 years old (range 37 to 57 years old), whereas AA was more frequent in men (61
) with a median age of 28 years old (range 15 to 46 years old). Leukocyte count, neutrophils and C-reactive protein were respectively 13,300 per mm3 (range 10,700 to 15,700 per mm3), 87.1
(range 84.6 to 89.6
) and 1.82 mg/dL (range 0.59 to 5.31 mg/dL) in AD versus 14,700 per mm3 (range 12,300 to 17,600 per mm), 81.6
(range 75.1 to 86.4
) and 2.71 mg/dL (range 0.67 to 75 mg/dL) in AA. Alvarado score and appendicitis diagnostic score were respectively 7 (range 6 to 8) and 6 (range 5 to 7) in AD and 7 (range 5 to 7) and 6 (range 5 to 6) in AA. An appendiceal perforation was seen in 3 AD (43
) and 80 AA (18
). CONCLUSION: AD appeared in older patients with a clinical and blood test profile similar to AA but with a higher perforation rate.
Asunto(s)
Apendicitis/diagnóstico , Diverticulitis/diagnóstico , Enfermedad Aguda , Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto JovenRESUMEN
BACKGROUND: Appendiceal diverticulitis (AD) is a rare cause of acute appendicitis (AA) which is most frequently diagnosed after appendectomy in pathological study. OBJECTIVE: To compare AA versus AD. METHODS: Retrospective analytic study in avperiod of 51 months fom January 2009 to March 2013 in the Hospital Universitario San Juan de Alicante (Spain), including patients with clinical or radiological suspicious of acute appendicitis which was confirmed intraoperatively and with the pathological study. RESULTS: We included 449 patients, 442 typical AA (98.5
) and 7AD (1.5
). DA was more frequent in women (57
) with a median age of 44 years old (range 37 to 57 years old), whereas AA was more frequent in men (61
) with a median age of 28 years old (range 15 to 46 years old). Leukocyte count, neutrophils and C-reactive protein were respectively 13,300 per mm3 (range 10,700 to 15,700 per mm3), 87.1
(range 84.6 to 89.6
) and 1.82 mg/dL (range 0.59 to 5.31 mg/dL) in AD versus 14,700 per mm3 (range 12,300 to 17,600 per mm), 81.6
(range 75.1 to 86.4
) and 2.71 mg/dL (range 0.67 to 75 mg/dL) in AA. Alvarado score and appendicitis diagnostic score were respectively 7 (range 6 to 8) and 6 (range 5 to 7) in AD and 7 (range 5 to 7) and 6 (range 5 to 6) in AA. An appendiceal perforation was seen in 3 AD (43
) and 80 AA (18
). CONCLUSION: AD appeared in older patients with a clinical and blood test profile similar to AA but with a higher perforation rate.
Asunto(s)
Apendicitis/diagnóstico , Diverticulitis/diagnóstico , Adolescente , Adulto , Adulto Joven , Enfermedad Aguda , Estudios Retrospectivos , Femenino , Humanos , Anciano , Masculino , Persona de Mediana EdadRESUMEN
Acute appendicitis is the most common abdominal surgical emergency. Atypical presentations lead to a late diagnosis with a higher complication rate. Given its rarity, we report a case of a thoracic empyema due to subphrenic appendicitis.
Asunto(s)
Apendicitis/complicaciones , Empiema Pleural/etiología , Absceso Subfrénico/etiología , Enfermedad Aguda , Anciano , Apendicitis/diagnóstico , Apendicitis/cirugía , Drenaje , Empiema Pleural/diagnóstico , Humanos , Masculino , Absceso Subfrénico/diagnóstico , Absceso Subfrénico/cirugíaRESUMEN
Lost gallstones after accidental opening of the gallbladder during cholecystectomy usually under laparoscopy, can cause late complications. Intra-abdominal abscess is the most frequent and the diagnosis is based on imaging techniques (abdominal ultrasound or computed tomography scan). Surgical drainage with gallstones removal seems to be the best approach, due to the fact that a simple percutaneous drainage has a high failure rate. However, a posterior abdominal wall abscess as the initial manifestation of intra-abdominal abscess due to retained gallstones is uncommon, and this prompted us to report this case.
Asunto(s)
Absceso Abdominal/etiología , Cálculos Biliares/complicaciones , Absceso Abdominal/diagnóstico por imagen , Absceso Abdominal/cirugía , Anciano , Colecistectomía , Drenaje , Cálculos Biliares/cirugía , Humanos , Masculino , Radiografía AbdominalRESUMEN
Los cálculos abandonados tras apertura accidental durante una colecistectomía, generalmente laparoscópica, pueden producir complicaciones tardías, siendo el absceso intraabdominal la más frecuente. El diagnóstico se basa en la prueba de imagen (ecografía/tomografía computerizada), siendo el drenaje y la extracción quirúrgica de los cálculos la mejor opción terapéutica, ya que el drenaje percutáneo presenta una elevada tasa de fracasos. Sin embargo, el absceso en pared abdominal posterior como manifestación inicial de un absceso intraabdominal debido a colelitiasis retenida es poco frecuente, por lo que reportamos este caso.
Lost gallstones after accidental opening of the gallbladder during cholecystectomy usually under laparoscopy, can cause late complications. Intra-abdominal abscess is the most frequent and the diagnosis is based on imaging techniques (abdominal ultrasound or computed tomography scan). Surgical drainage with gallstones removal seems to be the best approach, due to the fact that a simple percutaneous drainage has a high failure rate. However, a posterior abdominal wall abscess as the initial manifestation of intra-abdominal abscess due to retained gallstones is uncommon, and this prompted us to report this case.