RESUMEN
Ten days after inoculation of sarcomatous homogenate in the leg muscle of chickens, the appearance of sarcomatous tumours was observed by electron microscopy. Viral replication and cell transformation strongly altered phospholipids and glycolipids content of the tissue: 6.12 +/- 0.23 micromoles phospholipid phosphorus/g tissue in normal tissue and 3.5 +/- 0.19 micromoles phosphorus/g tissue in sarcomatous tissue. The concentration of lipid-bound sialic acids in normal tissues was 10.5 +/- 0 nmoles/g tissue and 24.27 +/- 0.8 nmoles/g tissue in sarcomatous tissue.
Asunto(s)
Gangliósidos/metabolismo , Fosfolípidos/metabolismo , Sarcoma Aviar/metabolismo , Animales , Animales Recién Nacidos , Virus del Sarcoma Aviar/fisiología , Transformación Celular Neoplásica/metabolismo , Pollos , Cromatografía en Capa Delgada , Gangliósidos/análisis , Músculos/química , Músculos/metabolismo , Trasplante de Neoplasias , Fosfolípidos/análisis , Sarcoma Aviar/química , Sarcoma Aviar/microbiología , Virión/fisiología , Replicación ViralRESUMEN
Cytological examination of superficial epithelial cells systematically sampled at the level of the navicular fossa of the urethra in 61 patients with prosthatic carcinoma that had underwent surgery or that had not been operated, in whom longterm treatment with oestrogens was applied led to the conclusion that the caryopyknotic index shows variable increases, in some cases attaining more than 30-40%, in direct connection with the amount and the duration of administration of the oestrogen substances. The results obtained are encouraging and suggest the possibility to apply an objective test in the application and the evaluation of the efficiency of a hormonal treatment.