RESUMEN
AIM: To eva luate the effect of subgingival placement of doxycy-cline in the form of a resorbable membrane on the clinical and microbiological parameters in the treatment of inflammatory periodontal disease. Material and methods; We evaluated the effects of a controlled release system containing doxycycline both in vivo and in vitro conditions. Drug systems were prepared for both, and a total of 19 patients were included in the study with age range from 35 to 50 years. Clinical parameters like gingival index, probing depth, attachment loss, and gingival shrinkage were evaluated along with microbiological evaluation as well for a period of 10 weeks. RESULTS: In vitro study showed that the doxycycline hydroxy-propyl methylcellulose films are capable of releasing the drug in a sustained way with respect to time. It was observed that the gingival index score, periodontal probing depth, and gingival shrinkage showed low levels at the doxycycline-treated sites as compared to the placebo group. The microbial culture results also showed a marked reduction in the total anaerobic count post-treatment and till the end of the 10 week study period in the doxycycline-treated group. Thus, overall results showed that 30% doxycycline methylcellulose strips have significant effects and benefits on clinical and microbial parameters in more than 5 mm deep periodontal pockets. CONCLUSION: We conclude that 30% doxycycline both in vivo and vitro study has proven to be an effective antibiotic of choice both clinically and microbiologically. CLINICAL SIGNIFICANCE: Doxycycline has proven to have great promise as an antibiotic of choice. Thus, there is a significant advantage in the clinical use of doxycycline formulation for both the therapist and the patient. It can help dental professionals as an additional means to maintain an improved clinical health in periodontal problems of their patients. With this new therapeutic modality, we can augment the ability to treat periodontitis more effectively.
Asunto(s)
Antibacterianos/administración & dosificación , Periodontitis Crónica/tratamiento farmacológico , Periodontitis Crónica/microbiología , Doxiciclina/administración & dosificación , Encía , Adulto , Periodontitis Crónica/diagnóstico , Sistemas de Liberación de Medicamentos/métodos , Femenino , Humanos , Técnicas In Vitro , Masculino , Persona de Mediana Edad , Índice Periodontal , Resultado del TratamientoRESUMEN
AIM: Diagnosis in orthodontic cases and treatment planning is a precise assessment of sagittal jaw relationship. A number of angular and linear measurements have been used to attain correct diagnosis. The present study is done to compare beta angle and A point-nasion-B point (ANB) angle for sagittal skeletal discrepancies. MATERIALS AND METHODS: A total of 105 subjects were included in between the age group of 18 and 24 years and were categorized based on the skeletal patterns as class I, class II, and class III having a sample of 35 in each group. Based on the ANB angle and patients' profile, the sample was divided into different skeletal groups. Beta angle is the angle amid the perpendicular from C to B line through point A and the A-B line. Analysis of variance (ANOVA) and post hoc Scheffe's test were applied to analyze dependent variables. The level of significance was set at p-value 0.05. RESULTS: The mean scores of ANB for class I skeletal pattern were 2.46 ± 0.460, for class II, 5.64 ± 1.258, and for class III, -1.03 ± 1.618. Similarly, significant differences were observed in beta angle for class I skeletal pattern as 31.71 ± 3.885, for class II, 24.97 ± 2.162, and for class III, 39.26 ± 3.649. CONCLUSION: Both ANB and beta angle showed significant differences with different skeletal patterns. CLINICAL SIGNIFICANCE: Both ANB and beta angle are awfully supportive diagnostic measurements to scrutinize sagittal jaw relationship.
Asunto(s)
Cefalometría/métodos , Maxilares/patología , Adolescente , Humanos , Maloclusión/diagnóstico , Maloclusión/patología , Mandíbula/patología , Maxilar/patología , Cráneo/patología , Adulto JovenRESUMEN
BACKGROUND: During orthodontic tooth movement friction occurs at the bracket wire interface. Out of the total force applied to the tooth movement, some of it is dissipated as friction, and the remainder is transferred to the supporting structures of the tooth to mediate tooth movement. However many factors affect friction, and method of arch wire ligation being an important contributing factor. Hence, this study was carried out to evaluate the effects of different ligature materials on friction in sliding mechanics and to compare the effect of environment (dry and wet) on friction produced in sliding mechanics. MATERIALS AND METHODS: The evaluation of friction between the bracket and the archwire consisted of a simulated half arch fixed appliance with archwire ligated in a vertical position. Four 0.022" maxillary stainless steel premolar brackets having a - 0° torque and 0° angulation were aligned with a 0.019" × 0.025" stainless steel arch wire onto a rigid Plexiglass sheet. The movable test bracket was fitted with a 10 mm long, 0.045" thick stainless steel power arm on the bonding surface. Testing was performed on a Hounsfield material testing machine. A total of 100 g weight was suspended from the power arm and the load needed to move the bracket over the distance of not <4 mm across the central span was recorded separately. Fifteen representative readings were taken with one reading per test sample. RESULTS: The results showed that the mean frictional force of different groups in dry and wet state was statistically significantly different. The mean frictional force in a dry state was statistically significantly higher than wet state in elastomeric group. CONCLUSION: The type of ligation material and environment significantly affected the degree of friction generated during sliding mechanics. Teflon coated stainless steel ligatures produced the least friction among the materials tested in both dry and wet conditions and there was no significant effect on friction in this group caused due to lubrication.